SF3B4 and EFTUD2

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		SF3B4	EFTUD2
Gene Name		splicing factor 3b, subunit 4, 49kDa	elongation factor Tu GTP binding domain containing 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex	Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Membrane Nuclear Speck Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Positive Regulation Of MRNA Splicing, Via Spliceosome	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 20881960 18391951)
Protein-Protein Interactions		42 interactors: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 NCK2 NUB1 PPP1R16B PRPF40A RBM39 RBM4 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 UBASH3A UBC WBP4 WDR77 ZCCHC10	16 interactors: ARPC3 CYFIP1 GOLM1 GSK3B HINFP HSPB1 LSM8 PIN1 PRPF6 PRPF8 SF1 SF3B3 SF3B4 SNRNP40 SREK1 WBP4
Entrez ID		10262	9343
HPRD ID		12028	04869
Ensembl ID		ENSG00000143368	ENSG00000108883
Uniprot IDs		B3KUJ0 Q15427	B3KX19 B4DMC0 K7EJ81 Q15029
PDB IDs		1X5T 1X5U
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of Gene Expression Circadian Regulation Of Translation Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Development Cellular Response To Growth Factor Stimulus Regulation Of ERBB Signaling Pathway Response To Growth Factor Negative Regulation Of Protein Metabolic Process Immune System Process Response To External Stimulus Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Development Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Signal Transduction Regulation Of Cellular Process Stress-activated MAPK Cascade Fc Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process	RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Processing MRNA Metabolic Process RNA Processing Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly Positive Regulation Of Cellular Metabolic Process Spliceosomal Complex Assembly Ribonucleoprotein Complex Biogenesis Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Negative Regulation Of Phosphorylation Positive Regulation Of Organelle Organization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Gene Expression Regulation Of Organelle Organization Hypermethylation Of CpG Island Primary Sex Determination Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Cellular Biosynthetic Process MRNA 3'-splice Site Recognition Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Interleukin-3 Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Female Gonad Development Positive Regulation Of Metabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Neuron Maturation Axonogenesis Negative Regulation Of MAPK Cascade Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Protein Localization To Microtubule Positive Regulation Of Actin Nucleation Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Protein Complex Assembly
Tagcloud ?			3k36me3 antagonizing arranged bromo bs69 called chromatin connects decorated depends h3k36me3 identifies intron ir modalities phd pwwp reader recognizes remarkably retention reveals snrnp spliceosome splicing tandemly trimethylation u5 zmynd11
Tagcloud (Difference) ?			3k36me3 antagonizing arranged bromo bs69 called chromatin connects decorated depends h3k36me3 identifies intron ir modalities phd pwwp reader recognizes remarkably retention reveals snrnp spliceosome splicing tandemly trimethylation u5 zmynd11
Tagcloud (Intersection) ?