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SF3B4 and BMPR1A
Number of citations of the paper that reports this interaction (PMID
15351706
)
4
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo, two hybrid)
SF3B4
BMPR1A
Gene Name
splicing factor 3b, subunit 4, 49kDa
bone morphogenetic protein receptor, type IA
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
U12-type Spliceosomal Complex
Plasma Membrane
Caveola
Integral Component Of Membrane
Dendrite
Neuronal Cell Body
Molecular Function
Nucleotide Binding
Protein Binding
Poly(A) RNA Binding
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Receptor Signaling Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta-activated Receptor Activity
Protein Binding
ATP Binding
Protein Homodimerization Activity
SMAD Binding
Metal Ion Binding
Biological Process
RNA Splicing, Via Transesterification Reactions
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Positive Regulation Of MRNA Splicing, Via Spliceosome
In Utero Embryonic Development
Mesoderm Formation
Somitogenesis
Mullerian Duct Regression
Positive Regulation Of Mesenchymal Cell Proliferation
Endocardial Cushion Formation
Transcription From RNA Polymerase II Promoter
Protein Phosphorylation
Immune Response
Transforming Growth Factor Beta Receptor Signaling Pathway
Ectoderm Development
Dorsal/ventral Axis Specification
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Neural Crest Cell Development
Stem Cell Maintenance
Pituitary Gland Development
Neural Plate Mediolateral Regionalization
Signal Transduction By Phosphorylation
Lung Development
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Hindlimb Morphogenesis
Odontogenesis Of Dentin-containing Tooth
Embryonic Digit Morphogenesis
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription, DNA-templated
Paraxial Mesoderm Structural Organization
Lateral Mesoderm Development
Regulation Of Lateral Mesodermal Cell Fate Specification
Mesendoderm Development
Embryonic Organ Development
Developmental Growth
Positive Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Neurogenesis
Cartilage Development
Palate Development
Positive Regulation Of SMAD Protein Import Into Nucleus
Heart Formation
Regulation Of Cellular Senescence
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Signaling by BMP
Drugs
Diseases
GWAS
Height (
20881960
18391951
)
Protein-Protein Interactions
42 interactors:
APBB1
BAG3
BAIAP2
BMPR1A
CHERP
CWF19L2
DDX17
DDX42
EFTUD2
EWSR1
FKBP1A
FRK
GRB2
HNRNPD
HNRNPF
HNRNPH1
HNRNPUL1
HSPB7
ILF3
ITSN1
MAPK9
METTL17
NCK2
NUB1
PPP1R16B
PRPF40A
RBM39
RBM4
SEC24D
SF1
SF3B2
SRSF6
SS18L1
STK19
SUMO4
TCAF1
TCERG1
UBASH3A
UBC
WBP4
WDR77
ZCCHC10
23 interactors:
ACVR1
BAMBI
BMP2
BMP4
BMP5
BMP6
BMP7
BMPR1B
BMPR2
FKBP1A
FKBP1B
GDF5
GDF6
GDF9
HOXC8
NEDD4
NEDD4L
SF3B4
SMAD1
TAB1
TGFBRAP1
USP15
ZMYND11
Entrez ID
10262
657
HPRD ID
12028
03192
Ensembl ID
ENSG00000143368
Uniprot IDs
B3KUJ0
Q15427
P36894
PDB IDs
1X5T
1X5U
1ES7
1REW
2GOO
2H62
2H64
2K3G
2QJ9
2QJA
2QJB
3NH7
3QB4
Enriched GO Terms of Interacting Partners
?
RNA Processing
RNA Splicing
MRNA Processing
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Circadian Regulation Of Translation
Regulation Of Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
RNA Biosynthetic Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Metabolic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neuron Projection Development
Cellular Response To Growth Factor Stimulus
Regulation Of ERBB Signaling Pathway
Response To Growth Factor
Negative Regulation Of Protein Metabolic Process
Immune System Process
Response To External Stimulus
Regulation Of Circadian Rhythm
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Neuron Development
Posttranscriptional Regulation Of Gene Expression
Positive Regulation Of Signal Transduction
Regulation Of Cellular Process
Stress-activated MAPK Cascade
Fc Receptor Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
BMP Signaling Pathway
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
SMAD Protein Signal Transduction
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Cartilage Development
Positive Regulation Of Bone Mineralization
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Ossification
Positive Regulation Of Signal Transduction
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Regulation Of Signaling
Cartilage Development
Cell Surface Receptor Signaling Pathway
Regulation Of RNA Metabolic Process
Positive Regulation Of Cell Differentiation
Positive Regulation Of Neuron Differentiation
Regulation Of Osteoblast Differentiation
Regulation Of Signal Transduction
Positive Regulation Of Cell Development
Regulation Of Bone Mineralization
Positive Regulation Of Protein Metabolic Process
Connective Tissue Development
Regulation Of Gene Expression
Regulation Of Neuron Differentiation
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Cartilage Development
Regulation Of Transcription, DNA-templated
Positive Regulation Of Neurogenesis
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Cell Development
Regulation Of Phosphorus Metabolic Process
Regulation Of Ossification
Positive Regulation Of Protein Modification Process
Growth
Regulation Of Neurogenesis
Regulation Of Cell Differentiation
Positive Regulation Of Protein Phosphorylation
Regulation Of Phosphorylation
Response To Organic Substance
Skeletal System Development
Tagcloud
?
abundant
adenomatosis
apcdd1
bmp5
closure
destinies
dictated
dkk2
e15
edge
eyelid
eyelids
fetuses
fgfr2
gli2
identities
ie
jag1
lcm
le
microdissection
morphogenetic
notch1
opening
polyposis
ptch1
shh
smo
tip
Tagcloud (Difference)
?
abundant
adenomatosis
apcdd1
bmp5
closure
destinies
dictated
dkk2
e15
edge
eyelid
eyelids
fetuses
fgfr2
gli2
identities
ie
jag1
lcm
le
microdissection
morphogenetic
notch1
opening
polyposis
ptch1
shh
smo
tip
Tagcloud (Intersection)
?