SF3B4 and HNRNPUL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SF3B4	HNRNPUL1
Description		splicing factor 3b subunit 4	heterogeneous nuclear ribonucleoprotein U like 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U2 SnRNP U12-type Spliceosomal Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm Synapse Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Splicing Factor Binding	RNA Binding Protein Binding Enzyme Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing U2-type Prespliceosome Assembly	Alternative MRNA Splicing, Via Spliceosome RNA Processing Response To Virus
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Birth length ( 25281659) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Height ( 18391951 20881960 31562340) Infant length ( 25281659) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 28869591) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		115 interacting genes: APBB1 BAG3 BAG4 BAIAP2 BMPR1A CD2BP2 CHERP CPSF7 CTTN CWF19L2 DDX17 DDX42 DMRTB1 EEF1A1 EFTUD2 EWSR1 FARSB FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 KHDRBS2 MAPK9 METTL17 MIR1-1 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR141 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18B MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-3 MIR9-1 MIR92A1 MIR92A2 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NCK2 NUB1 OGT PPP1R16B PRPF6 QARS1 RAMAC RBFOX2 RBM10 RBM39 RBM4 RPP25 SEC24D SF1 SF3B2 SFPQ SRSF6 SS18L1 SUMO4 TCAF1 TCERG1 TFG TLE5 TRAF4 UBASH3A WBP4 WDR4 WDR77 WHR1 ZCCHC10 ZNF3 ZNF48	56 interacting genes: BRD7 CEBPA CRMP1 DMRTB1 DZIP3 EP300 ERG ERG28 EWSR1 FOXP1 FXR1 GIT2 HNRNPF HNRNPH2 HNRNPH3 IL7R ITCH KLHDC7B MAPK1IP1L MARS1 MED31 NEDD4 NXF1 NXF2 NXF3 PIAS2 PIAS4 PPIL1 PPP1R13B PRMT1 PRMT2 PRPF40A PTEN RBM22 RBM4 RBM4B ROPN1 RPA1 RPA2 SF1 SF3B4 SMN1 SMN2 SNRPB2 SNRPC SORBS3 SRSF9 TGM2 TLX3 TMEM132D TP53 TP53BP2 VPS37C WWP2 YAP1 ZNF207
Entrez ID		10262	11100
HPRD ID		12028	10428
Ensembl ID		ENSG00000143368	ENSG00000105323
Uniprot IDs		B3KUJ0 Q15427	A0A0A0MRA5 A8K3W4 B7Z4B8 Q9BUJ2
PDB IDs		1X5T 5GVQ 5Z56 5Z57 5Z58 6AH0 6AHD 6QX9 6Y53 6Y5Q 7ABG 7ABH 7ABI 7DVQ 7EVO 7ONB 7QTT 7VPX 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y7E	1ZRJ
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity RISC Complex Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Regulation Of MRNA Metabolic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Vasculature Development Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of RNA Stability Regulation Of MRNA Stability Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cytokine Production Negative Regulation Of Protein Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of Multicellular Organismal Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Sprouting Angiogenesis MRNA Processing Negative Regulation Of Signal Transduction Regulation Of Cell Migration Regulation Of Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Locomotion Regulation Of Cell Motility	Nucleoplasm RNA Splicing Nucleus Nucleic Acid Binding RNA Binding MRNA Processing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing Spliceosomal Complex Macromolecule Metabolic Process Spliceosomal Complex Assembly Nuclear RNA Export Factor Complex PML Body Negative Regulation Of Cell Cycle Regulation Of RNA Splicing Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition P53 Binding Transcription Coregulator Activity Protein-RNA Complex Assembly Regulation Of Androgen Receptor Signaling Pathway Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition MRNA Binding MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Chromatin U1 SnRNP Protein-containing Complex Assembly Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Entrainment Of Circadian Clock By Photoperiod Poly(A)+ MRNA Export From Nucleus Cajal Body Regulation Of Cell Development Negative Regulation Of Mitotic Cell Cycle Nuclear Matrix Circadian Rhythm Regulation Of Macromolecule Metabolic Process Nuclear Androgen Receptor Binding
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