SF3B4 and CWF19L2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SF3B4	CWF19L2
Gene Name		splicing factor 3b, subunit 4, 49kDa	CWF19-like 2, cell cycle control (S. pombe)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	Catalytic Activity
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Positive Regulation Of MRNA Splicing, Via Spliceosome	Metabolic Process
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 20881960 18391951)
Protein-Protein Interactions		42 interactors: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 NCK2 NUB1 PPP1R16B PRPF40A RBM39 RBM4 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 UBASH3A UBC WBP4 WDR77 ZCCHC10	27 interactors: APP BRCA1 CALCOCO1 CALCOCO2 CARD9 CCDC136 CCDC57 FAM9B HOOK2 KRT40 LHX9 LZTS2 MAD1L1 MEOX1 MTUS2 NAB2 NDEL1 RINT1 SF3B4 STX11 TAX1BP1 TP53BP2 TRIM27 TRIM37 TRIM54 TRIM9 VIM
Entrez ID		10262	143884
HPRD ID		12028	13102
Ensembl ID		ENSG00000143368	ENSG00000152404
Uniprot IDs		B3KUJ0 Q15427	Q2TBE0
PDB IDs		1X5T 1X5U
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of Gene Expression Circadian Regulation Of Translation Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Development Cellular Response To Growth Factor Stimulus Regulation Of ERBB Signaling Pathway Response To Growth Factor Negative Regulation Of Protein Metabolic Process Immune System Process Response To External Stimulus Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Development Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Signal Transduction Regulation Of Cellular Process Stress-activated MAPK Cascade Fc Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process	Negative Regulation Of Centriole Replication Intracellular Receptor Signaling Pathway Regulation Of Centriole Replication Regulation Of Cell Cycle Process Innate Immune Response Negative Regulation Of Centrosome Duplication Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Cellular Component Organization Regulation Of Transcription From RNA Polymerase III Promoter Establishment Of Localization In Cell Intracellular Transport Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cellular Process Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process Microtubule-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Negative Regulation Of Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Centrosome Duplication Protein Autoubiquitination Establishment Of Vesicle Localization Immune Response Cellular Localization Vesicle Localization Regulation Of Centrosome Cycle Axon Cargo Transport Centrosome Cycle Cell Cycle Defense Response Gonad Morphogenesis Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Regulation Of Metaphase Plate Congression Regulation Of Cytoskeleton Organization Secretion By Cell Organelle Organization Synaptic Vesicle Exocytosis Regulation Of Cytokine Production Vesicle-mediated Transport Cellular Process Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Gene Expression
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