DDX42 and DHX15

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		DDX42	DHX15
Description		DEAD-box helicase 42	DEAH-box helicase 15
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Membrane Nuclear Speck U2-type Prespliceosome	Nucleus Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Nucleolus Nuclear Speck U2-type Post-mRNA Release Spliceosomal Complex
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Double-stranded RNA Binding Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On RNA Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Intracellular Protein Localization Regulation Of Apoptotic Process U2-type Prespliceosome Assembly	MRNA Splicing, Via Spliceosome Immune System Process MRNA Processing RNA Splicing Response To Toxic Substance Defense Response To Bacterium Positive Regulation Of Canonical NF-kappaB Signal Transduction Response To Alkaloid Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 25673413) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 25673412)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Myopia (pathological) ( 23049088) Pulmonary emphysema ( 24383474) Sense of smell ( 26632684)
Interacting Genes		13 interacting genes: APP DHX15 FBXO25 LINC00624 MAILR MDM2 PRPF19 RECQL5 RNF10 SF3A1 SF3B4 SNRPC U2SURP	23 interacting genes: AGGF1 APBB1 CAMSAP3 CEBPA DDX42 DYSF FXR1 GPANK1 KRT75 NKAP NKRF PIN1 PRPF40A PTEN PTP4A2 SPOP TRA2A UBC USP7 WBP4 YWHAB YWHAG ZGPAT
Entrez ID		11325	1665
HPRD ID		09909	04553
Ensembl ID		ENSG00000198231	ENSG00000109606
Uniprot IDs		Q86XP3	O43143
PDB IDs		7EVN 8DPE 8HK1	5XDR 6ID1 6SH6 6SH7 8EJM 8RO2
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions U2 SnRNP RNA Splicing Spliceosomal Complex Assembly MRNA Processing Protein-RNA Complex Assembly RNA Processing Response To Alkaloid Nucleic Acid Binding MRNA Metabolic Process U2-type Prespliceosome Protein-containing Complex Assembly U12-type Spliceosomal Complex U2-type Prespliceosome Assembly Amyloid Fibril Formation U2-type Spliceosomal Complex MRNA Splice Site Recognition Protein-containing Complex Organization Cellular Response To Alkaloid Macromolecule Metabolic Process Spliceosomal SnRNP Assembly Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Nucleus Response To Formaldehyde Cellular Response To Vitamin B1 U2-type Precatalytic Spliceosome Ubiquitin-protein Transferase Activity Protein Ubiquitination Protein Autoubiquitination Acetylcholine Receptor Activator Activity Lipoprotein Particle Regulation Of Receptor Internalization Positive Regulation Of Protein Import Protein Modification By Small Protein Conjugation Mitotic DNA-templated DNA Replication PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization	Nucleic Acid Binding Nuclear Speck Negative Regulation Of Macromolecule Metabolic Process Phosphoserine Residue Binding Nucleoplasm Negative Regulation Of Metabolic Process Nucleus Ubiquitin Ligase Activator Activity Negative Regulation Of Protein Metabolic Process RNA Binding MRNA Cis Splicing, Via Spliceosome Proline-rich Region Binding Protein Stabilization U2-type Prespliceosome Negative Regulation Of Protein Phosphorylation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Hematopoietic Stem Cell Proliferation Regulation Of Protein Metabolic Process Dentate Gyrus Development Negative Regulation Of Phosphorylation Granulocyte Differentiation Molecular Function Inhibitor Activity Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Cell Cycle RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Protein Stability Cis-trans Isomerase Activity Phosphoprotein Binding Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Phosphate Metabolic Process Monocyte Activation Involved In Immune Response Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Regulation Of Protein Phosphorylation Protein Sequestering Activity
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