SF3B4 and METTL17

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SF3B4	METTL17
Gene Name		splicing factor 3b, subunit 4, 49kDa	methyltransferase like 17
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex	Nucleus Nucleoplasm Mitochondrion Ribosome
	Molecular Function	Nucleotide Binding Protein Binding Poly(A) RNA Binding	Copper Ion Binding Protein Binding Methyltransferase Activity
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Positive Regulation Of MRNA Splicing, Via Spliceosome	Translation Methylation
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Height ( 20881960 18391951)
Protein-Protein Interactions		42 interactors: APBB1 BAG3 BAIAP2 BMPR1A CHERP CWF19L2 DDX17 DDX42 EFTUD2 EWSR1 FKBP1A FRK GRB2 HNRNPD HNRNPF HNRNPH1 HNRNPUL1 HSPB7 ILF3 ITSN1 MAPK9 METTL17 NCK2 NUB1 PPP1R16B PRPF40A RBM39 RBM4 SEC24D SF1 SF3B2 SRSF6 SS18L1 STK19 SUMO4 TCAF1 TCERG1 UBASH3A UBC WBP4 WDR77 ZCCHC10	14 interactors: ATXN1 ATXN1L CALCOCO2 CEP70 KRT40 MAPK6 MDFI MID2 PNMA1 SF3B4 SPERT TFIP11 TRAF1 TRIP6
Entrez ID		10262	64745
HPRD ID		12028	13379
Ensembl ID		ENSG00000143368	ENSG00000165792
Uniprot IDs		B3KUJ0 Q15427	Q9H7H0
PDB IDs		1X5T 1X5U
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of RNA Metabolic Process Regulation Of Gene Expression Circadian Regulation Of Translation Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Projection Development Cellular Response To Growth Factor Stimulus Regulation Of ERBB Signaling Pathway Response To Growth Factor Negative Regulation Of Protein Metabolic Process Immune System Process Response To External Stimulus Regulation Of Circadian Rhythm Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neuron Development Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Signal Transduction Regulation Of Cellular Process Stress-activated MAPK Cascade Fc Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process	Lung Alveolus Development Regulation Of RNA Metabolic Process Spliceosomal Complex Disassembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Release Of Cytoplasmic Sequestered NF-kappaB RNA Processing Negative Regulation Of Gene Expression Regulation Of Protein Import Into Nucleus Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Localization To Microtubule Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity MAPK Cascade MRNA Splicing, Via Spliceosome Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Splicing, Via Transesterification Reactions Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Signal Transduction Lung Development Respiratory Tube Development Regulation Of Intracellular Protein Transport Negative Regulation Of Viral Release From Host Cell Regulation Of Signal Transduction Signal Transduction By Phosphorylation Negative Regulation Of Viral Entry Into Host Cell Respiratory System Development Trophoblast Giant Cell Differentiation
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