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MED8 and MED31
Number of citations of the paper that reports this interaction (PMID
12149480
)
28
Data Source:
HPRD
(in vitro)
MED8
MED31
Gene Name
mediator complex subunit 8
mediator complex subunit 31
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mediator Complex
Nucleoplasm
Mediator Complex
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
Protein Complex Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Protein Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Protein Complex Assembly
Gene Expression
Negative Regulation Of Fibroblast Proliferation
Limb Development
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
31 interactors:
APP
ARRB2
CCNC
CDK8
CTDP1
HSPB3
KRT40
MED1
MED11
MED12
MED17
MED19
MED20
MED22
MED25
MED26
MED27
MED28
MED30
MED31
MED6
MED7
MED9
PEX14
PHYHIP
PNMA1
SNTA1
TCEB1
THOC7
UBALD1
USP49
58 interactors:
AES
AGR2
ANXA7
ASCC2
C2orf44
CACNB4
CCT7
CDKN1A
CPE
DAZAP2
DLEU1
DNM1
EEF1G
EGR2
EPN1
ERH
FAM118B
GADD45G
GSTM4
HGH1
HMOX2
HNRNPUL1
HSPB1
HSPB3
HTT
LAMA4
LYPLA2
MAFG
MED18
MED19
MED7
MED8
MED9
MOB4
NFATC2
NR4A1
ORAI2
PABPC4
PAFAH1B3
PFDN1
PMF1
PQBP1
PRMT1
PSMD11
RAB25
RBM23
RFC5
RPA2
SAT1
SELENBP1
SERPINB9
SMN1
TGIF1
TINAGL1
TK1
UBE2B
ZBTB45
ZSCAN1
Entrez ID
112950
51003
HPRD ID
06991
14382
Ensembl ID
ENSG00000159479
ENSG00000108590
Uniprot IDs
Q96G25
Q9Y3C7
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Metabolic Process
Biosynthetic Process
Stem Cell Maintenance
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Androgen Receptor Signaling Pathway
Stem Cell Development
Positive Regulation Of Gene Expression
Negative Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Stem Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of Cellular Process
Cellular Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Notch Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Binding
Regulation Of Cell Differentiation
Developmental Growth Involved In Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Binding
Cell Development
Negative Regulation Of Fibroblast Proliferation
Axis Elongation
Cellular Response To Transforming Growth Factor Beta Stimulus
Thyroid Hormone Mediated Signaling Pathway
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Cellular Metabolic Process
Transcription From RNA Polymerase II Promoter
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription, DNA-templated
RNA Metabolic Process
RNA Biosynthetic Process
Developmental Process
Biosynthetic Process
Regulation Of Gene Expression
Anatomical Structure Development
Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cell Differentiation
Multicellular Organismal Development
Response To Stimulus
Neurotransmitter Uptake
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Nucleotide-excision Repair, DNA Gap Filling
Negative Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Programmed Cell Death
Telomere Maintenance Via Semi-conservative Replication
System Development
Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Cell Death
Telomere Maintenance Via Recombination
Nuclear DNA Replication
Mitotic DNA Damage Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Mitotic DNA Integrity Checkpoint
Embryo Development Ending In Birth Or Egg Hatching
DNA-templated Transcription, Initiation
Response To External Stimulus
Regulation Of Cell Death
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
antigenic
arising
asxl1
bands
casp5
cms
colon
colonic
crebbp
decay
encode
ep300
examples
exon
fbxl3
frameshift
microsatellite
microsatellites
msh3
msi
neo
nmd
nonsense
rgs12
sfrs12ip1
targetable
termini
transcripts
ttk
Tagcloud (Difference)
?
antigenic
arising
asxl1
bands
casp5
cms
colon
colonic
crebbp
decay
encode
ep300
examples
exon
fbxl3
frameshift
microsatellite
microsatellites
msh3
msi
neo
nmd
nonsense
rgs12
sfrs12ip1
targetable
termini
transcripts
ttk
Tagcloud (Intersection)
?