MED31 and PQBP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED31	PQBP1
Gene Name		mediator complex subunit 31	polyglutamine binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mediator Complex	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Nuclear Speck Neuronal Ribonucleoprotein Granule
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Protein Binding Protein Complex Binding	DNA Binding Transcription Coactivator Activity Ribonucleoprotein Complex Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Protein Complex Assembly Gene Expression Negative Regulation Of Fibroblast Proliferation Limb Development	Alternative MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Neuron Projection Development Regulation Of RNA Splicing Regulation Of Dendrite Morphogenesis
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AES AGR2 ANXA7 ASCC2 C2orf44 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 UBE2B ZBTB45 ZSCAN1	23 interactors: APBB1 APP AQR ATXN1 C14orf1 CLTB EEF1A1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77
Entrez ID		51003	10084
HPRD ID		14382	02354
Ensembl ID		ENSG00000108590	ENSG00000102103
Uniprot IDs		Q9Y3C7	O60828
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Developmental Process Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Differentiation Multicellular Organismal Development Response To Stimulus Neurotransmitter Uptake Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Negative Regulation Of Programmed Cell Death Telomere Maintenance Via Semi-conservative Replication System Development Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Cell Death Telomere Maintenance Via Recombination Nuclear DNA Replication Mitotic DNA Damage Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Embryo Development Ending In Birth Or Egg Hatching DNA-templated Transcription, Initiation Response To External Stimulus Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Protein Metabolic Process	RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Visual Learning Visual Behavior Associative Learning Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Response To Light Stimulus Learning Regulation Of Protein Binding Nitrogen Compound Metabolic Process Mitotic Cell Cycle Cell Division Response To Radiation Negative Regulation Of Neuron Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Respiratory Gaseous Exchange Cell Cycle Regulation Of Neuron Differentiation Regulation Of Binding Learning Or Memory Neurohypophysis Development Synaptic Growth At Neuromuscular Junction Transcription, RNA-templated Cell Cycle Process Negative Regulation Of Neurogenesis Cognition Positive Regulation Of Microtubule Plus-end Binding Collateral Sprouting In Absence Of Injury Golgi Vesicle Fusion To Target Membrane Regulation Of Nitrogen Compound Metabolic Process Mitotic Nuclear Division Response To Abiotic Stimulus Positive Regulation Of Cellular Biosynthetic Process Ribonucleoprotein Complex Biogenesis Mitotic Cell Cycle Process Neuron Differentiation Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Development Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?			amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie
Tagcloud (Difference) ?			amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie
Tagcloud (Intersection) ?