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MED8 and PHYHIP
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
MED8
PHYHIP
Gene Name
mediator complex subunit 8
phytanoyl-CoA 2-hydroxylase interacting protein
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mediator Complex
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Protein Ubiquitination
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Hypertriglyceridemia (
23505323
)
Protein-Protein Interactions
31 interactors:
APP
ARRB2
CCNC
CDK8
CTDP1
HSPB3
KRT40
MED1
MED11
MED12
MED17
MED19
MED20
MED22
MED25
MED26
MED27
MED28
MED30
MED31
MED6
MED7
MED9
PEX14
PHYHIP
PNMA1
SNTA1
TCEB1
THOC7
UBALD1
USP49
24 interactors:
BAI1
C14orf1
COPS6
DYRK1A
EEF1A1
FAM131A
HDAC11
HNRNPA1
MAGED4B
MED8
METTL18
NDRG1
NDUFV3
NFE2
PHYH
PNPLA2
PPIE
PRMT5
S100A13
SMARCC2
SUPT5H
TTR
WDR89
ZZEF1
Entrez ID
112950
9796
HPRD ID
06991
16345
Ensembl ID
ENSG00000159479
ENSG00000168490
Uniprot IDs
Q96G25
Q92561
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Metabolic Process
Biosynthetic Process
Stem Cell Maintenance
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Androgen Receptor Signaling Pathway
Stem Cell Development
Positive Regulation Of Gene Expression
Negative Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Stem Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of Cellular Process
Cellular Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Notch Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Binding
Regulation Of Cell Differentiation
Developmental Growth Involved In Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Binding
Cell Development
Negative Regulation Of Fibroblast Proliferation
Axis Elongation
Cellular Response To Transforming Growth Factor Beta Stimulus
Thyroid Hormone Mediated Signaling Pathway
Nucleosome Disassembly
Chromatin Organization
Mast Cell Activation
MRNA Processing
RNA Metabolic Process
Cellular Metabolic Process
MRNA Metabolic Process
MRNA Splicing, Via Spliceosome
Interleukin-1 Alpha Secretion
RNA Splicing, Via Transesterification Reactions
Gene Expression
RNA Processing
Chromosome Organization
Chromatin Modification
Positive Regulation Of Viral Process
Nucleobase-containing Compound Metabolic Process
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Methyl-branched Fatty Acid Metabolic Process
Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Transcription, DNA-templated
RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
RNA Splicing
Glial Cell Development
Peripheral Nervous System Development
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment
Acylglycerol Acyl-chain Remodeling
Thyroid Hormone Transport
Isoprenoid Metabolic Process
Fatty Acid Alpha-oxidation
Interleukin-1 Secretion
Positive Regulation Of Spindle Checkpoint
Regulation Of RNA Metabolic Process
Tagcloud
?
antigenic
arising
asxl1
bands
casp5
cms
colon
colonic
crebbp
decay
encode
ep300
examples
exon
fbxl3
frameshift
microsatellite
microsatellites
msh3
msi
neo
nmd
nonsense
rgs12
sfrs12ip1
targetable
termini
transcripts
ttk
Tagcloud (Difference)
?
antigenic
arising
asxl1
bands
casp5
cms
colon
colonic
crebbp
decay
encode
ep300
examples
exon
fbxl3
frameshift
microsatellite
microsatellites
msh3
msi
neo
nmd
nonsense
rgs12
sfrs12ip1
targetable
termini
transcripts
ttk
Tagcloud (Intersection)
?