MED31 and SAT1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED31	SAT1
Gene Name		mediator complex subunit 31	spermidine/spermine N1-acetyltransferase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mediator Complex	Intracellular Cytosol
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Protein Binding Protein Complex Binding	Diamine N-acetyltransferase Activity Protein Binding Spermidine Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Protein Complex Assembly Gene Expression Negative Regulation Of Fibroblast Proliferation Limb Development	Angiogenesis Polyamine Metabolic Process Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Proliferation Small Molecule Metabolic Process
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	Metabolism of polyamines Interconversion of polyamines Metabolism of amino acids and derivatives
Drugs			N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AES AGR2 ANXA7 ASCC2 C2orf44 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 UBE2B ZBTB45 ZSCAN1	75 interactors: ABCB8 APLP1 B4GALT3 C14orf1 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CHD3 COPS6 CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DMRT3 DNPEP EEF1G EIF3D EPHB6 EVA1A FAM156A FAM69B FAM86C1 FTSJ3 FUNDC2 GBP2 GDF9 GNB2L1 HIF1A HOXB6 HOXB9 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KIAA1377 LNX1 LRIF1 LUC7L2 MED31 MRPL9 MTA1 NIF3L1 NMRK2 PLGRKT PRDX2 PTN RBM17 RBM48 REL RELA RPLP1 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TLE1 TP53 TP53TG1 TSC22D4 TUBB2A UBE2D3 UNC119 UTP14A VASP VKORC1 ZHX1
Entrez ID		51003	6303
HPRD ID		14382	02431
Ensembl ID		ENSG00000108590	ENSG00000130066
Uniprot IDs		Q9Y3C7	P21673 Q6ICU9
PDB IDs			2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Developmental Process Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Differentiation Multicellular Organismal Development Response To Stimulus Neurotransmitter Uptake Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Negative Regulation Of Programmed Cell Death Telomere Maintenance Via Semi-conservative Replication System Development Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Cell Death Telomere Maintenance Via Recombination Nuclear DNA Replication Mitotic DNA Damage Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Embryo Development Ending In Birth Or Egg Hatching DNA-templated Transcription, Initiation Response To External Stimulus Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Protein Metabolic Process	RNA Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Response To Radiation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Cellular Process Regulation Of RNA Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Response To External Stimulus Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Gene Expression Chemotaxis Response To Light Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Locomotion Regulation Of Interleukin-12 Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Response To Ionizing Radiation Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Axon Guidance Response To Abiotic Stimulus
Tagcloud ?			acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Difference) ?			acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Intersection) ?