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MED8 and MED27
Number of citations of the paper that reports this interaction (PMID
12584197
)
12
Data Source:
HPRD
(in vitro)
MED8
MED27
Gene Name
mediator complex subunit 8
mediator complex subunit 27
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mediator Complex
Nucleus
Nucleoplasm
Transcription Factor Complex
Nucleolus
Cytoplasm
Mediator Complex
Molecular Function
RNA Polymerase II Transcription Cofactor Activity
Protein Binding
Transcription Coactivator Activity
Protein Binding
Biological Process
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Protein Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Stem Cell Maintenance
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Generic Transcription Pathway
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions
31 interactors:
APP
ARRB2
CCNC
CDK8
CTDP1
HSPB3
KRT40
MED1
MED11
MED12
MED17
MED19
MED20
MED22
MED25
MED26
MED27
MED28
MED30
MED31
MED6
MED7
MED9
PEX14
PHYHIP
PNMA1
SNTA1
TCEB1
THOC7
UBALD1
USP49
9 interactors:
AFP
ARFGAP1
MED19
MED22
MED30
MED8
MED9
RBPJ
SOX5
Entrez ID
112950
9442
HPRD ID
06991
05438
Ensembl ID
ENSG00000159479
ENSG00000160563
Uniprot IDs
Q96G25
Q6P2C8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
RNA Metabolic Process
Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of Metabolic Process
Biosynthetic Process
Stem Cell Maintenance
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Androgen Receptor Signaling Pathway
Stem Cell Development
Positive Regulation Of Gene Expression
Negative Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Stem Cell Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Steroid Hormone Receptor Signaling Pathway
Regulation Of Cellular Process
Cellular Metabolic Process
Intracellular Receptor Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Notch Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Binding
Regulation Of Cell Differentiation
Developmental Growth Involved In Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Protein Binding
Cell Development
Negative Regulation Of Fibroblast Proliferation
Axis Elongation
Cellular Response To Transforming Growth Factor Beta Stimulus
Thyroid Hormone Mediated Signaling Pathway
Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Timing Of Cell Differentiation
Regulation Of Development, Heterochronic
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
DNA-templated Transcription, Initiation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Epidermal Cell Fate Specification
Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment
Positive Regulation Of Ephrin Receptor Signaling Pathway
Arterial Endothelial Cell Fate Commitment
Cellular Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Regulation Of Metabolic Process
Blood Vessel Lumenization
Blood Vessel Endothelial Cell Fate Specification
Nitrogen Compound Metabolic Process
Protein Secretion
Endothelial Cell Fate Specification
Stem Cell Maintenance
Clara Cell Differentiation
Positive Regulation Of Mesenchymal Stem Cell Differentiation
Interleukin-4 Secretion
Positive Regulation Of Transcription Of Notch Receptor Target
Regulation Of Cellular Process
Hair Follicle Maturation
Regulation Of Timing Of Neuron Differentiation
Auditory Receptor Cell Fate Commitment
Dorsal Aorta Morphogenesis
Arterial Endothelial Cell Differentiation
Regulation Of Mesenchymal Stem Cell Differentiation
Dorsal Aorta Development
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation
Endocardium Morphogenesis
Endothelial Tube Morphogenesis
Tagcloud
?
antigenic
arising
asxl1
bands
casp5
cms
colon
colonic
crebbp
decay
encode
ep300
examples
exon
fbxl3
frameshift
microsatellite
microsatellites
msh3
msi
neo
nmd
nonsense
rgs12
sfrs12ip1
targetable
termini
transcripts
ttk
Tagcloud (Difference)
?
antigenic
arising
asxl1
bands
casp5
cms
colon
colonic
crebbp
decay
encode
ep300
examples
exon
fbxl3
frameshift
microsatellite
microsatellites
msh3
msi
neo
nmd
nonsense
rgs12
sfrs12ip1
targetable
termini
transcripts
ttk
Tagcloud (Intersection)
?