MED31 and C2orf44

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED31	C2orf44
Gene Name		mediator complex subunit 31	chromosome 2 open reading frame 44
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Mediator Complex
	Molecular Function	RNA Polymerase II Transcription Cofactor Activity Protein Binding Protein Complex Binding	Kinase Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Protein Complex Assembly Gene Expression Negative Regulation Of Fibroblast Proliferation Limb Development	Protein Oligomerization
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AES AGR2 ANXA7 ASCC2 C2orf44 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 UBE2B ZBTB45 ZSCAN1	12 interactors: CSNK1E CSNK1G1 CSNK1G2 DYNC1I1 HCK MED31 PDPK1 PRKAR1A RAB35 RPS27 TAB1 TNNT1
Entrez ID		51003	80304
HPRD ID		14382	07972
Ensembl ID		ENSG00000108590	ENSG00000163026
Uniprot IDs		Q9Y3C7	Q9H6R7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Developmental Process Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Differentiation Multicellular Organismal Development Response To Stimulus Neurotransmitter Uptake Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Negative Regulation Of Programmed Cell Death Telomere Maintenance Via Semi-conservative Replication System Development Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Cell Death Telomere Maintenance Via Recombination Nuclear DNA Replication Mitotic DNA Damage Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Embryo Development Ending In Birth Or Egg Hatching DNA-templated Transcription, Initiation Response To External Stimulus Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Protein Metabolic Process	Regulation Of Cell Shape Peptidyl-serine Phosphorylation Peptidyl-amino Acid Modification Regulation Of Cell Morphogenesis Phosphorylation Cellular Response To Growth Factor Stimulus Protein Autophosphorylation Regulation Of Cellular Component Organization Response To Growth Factor Endocytosis Protein Phosphorylation Cell Surface Receptor Signaling Pathway Fc Receptor Signaling Pathway Activation Of Protein Kinase Activity Immune System Process Wnt Signaling Pathway Vesicle-mediated Transport Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Innate Immune Response Respiratory Burst After Phagocytosis Positive Regulation Of Phospholipase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transport Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Leukocyte Migration Involved In Immune Response Signal Transduction Response To Peptide Hormone Immune Response-regulating Signaling Pathway Phosphate-containing Compound Metabolic Process Positive Regulation Of Protein Kinase Activity Cellular Response To Organic Substance Cellular Response To Organonitrogen Compound Response To Peptide Positive Regulation Of Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Signaling Innate Immune Response-activating Signal Transduction Cell Communication Mesoderm Development Activation Of Innate Immune Response Positive Regulation Of Transferase Activity Respiratory Burst Involved In Defense Response Positive Regulation Of Protein Metabolic Process Positive Regulation Of Wnt Signaling Pathway Cellular Response To Hormone Stimulus Immune Response
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