CHTF8 and AP4M1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CHTF8	AP4M1
Description		chromosome transmission fidelity factor 8	adaptor related protein complex 4 subunit mu 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Ctf18 RFC-like Complex	Cytoplasm Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Membrane AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Extracellular Exosome
	Molecular Function	DNA Binding DNA Clamp Loader Activity Protein Binding Single-stranded DNA Helicase Activity	Protein Binding Protein Transmembrane Transporter Activity Protein Domain Specific Binding
	Biological Process	DNA Replication Mitotic Sister Chromatid Cohesion Positive Regulation Of DNA-directed DNA Polymerase Activity	Autophagosome Assembly Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Golgi To Endosome Transport Intracellular Protein Localization Protein Transport Vesicle-mediated Transport Protein Transmembrane Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane
Pathways		Polymerase switching on the C-strand of the telomere	Lysosome Vesicle Biogenesis
Drugs
Diseases			Cerebral palsy
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)	Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: AP4M1 DSCC1 EIF4EBP1 PCNA RFC3 WBP4	16 interacting genes: ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B HOOK1 HOOK2 KRTAP5-2 LAMP2 TGOLN2 USP47 ZBTB22
Entrez ID		54921	9179
HPRD ID		16797	03803
Ensembl ID		ENSG00000168802	ENSG00000221838
Uniprot IDs		P0CG13	C9JC87 C9JWL4 H7C0A0 O00189
PDB IDs			3L81 4MDR
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA-directed DNA Polymerase Activity Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA Biosynthetic Process Ctf18 RFC-like Complex DNA Clamp Loader Activity DNA Strand Elongation Involved In DNA Replication DNA Replication DNA Strand Elongation Single-stranded DNA Helicase Activity DNA Synthesis Involved In DNA Repair Positive Regulation Of DNA Metabolic Process Positive Regulation Of Catalytic Activity PCNA Complex Replisome DNA Biosynthetic Process Regulation Of DNA Metabolic Process PCNA-p21 Complex DNA Polymerase Processivity Factor Activity Regulation Of Catalytic Activity Regulation Of DNA Replication Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Protein Localization To Basolateral Plasma Membrane Post-translational Protein Acetylation Positive Regulation Of Deoxyribonuclease Activity DNA Metabolic Process Leading Strand Elongation AP-4 Adaptor Complex Maintenance Of Mitotic Sister Chromatid Cohesion DNA Replication Factor C Complex MutLalpha Complex Binding Telomere Maintenance Via Semi-conservative Replication Nucleic Acid Metabolic Process Eukaryotic Initiation Factor 4E Binding Estrous Cycle Golgi To Lysosome Transport Clathrin Adaptor Complex Nuclear Lamina Base-excision Repair, Gap-filling Golgi To Endosome Transport Translation Repressor Activity Nucleobase-containing Compound Metabolic Process Chromosome Organization MRNA Cis Splicing, Via Spliceosome Nuclear Replication Fork Response To L-glutamate Ovulation Cycle Golgi To Vacuole Transport Precatalytic Spliceosome	Postsynaptic Density Membrane Ligand-gated Monoatomic Ion Channel Activity Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, Glutamatergic Ligand-gated Ion Channel Signaling Pathway Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential FHF Complex Synaptic Transmission, Glutamatergic Intracellular Protein Localization Platelet Dense Granule Membrane Glutamate Receptor Signaling Pathway NMDA Glutamate Receptor Activity Protein Localization To Perinuclear Region Of Cytoplasm Excitatory Postsynaptic Potential NMDA Selective Glutamate Receptor Complex Glutamate-gated Calcium Ion Channel Activity Calcium Ion Transmembrane Transport Regulation Of Synaptic Plasticity Excitatory Chemical Synaptic Transmission Cellular Localization Regulation Of Synaptic Transmission, Glutamatergic Monoatomic Ion Transmembrane Transport Calcium Ion Transport HOPS Complex Modulation Of Chemical Synaptic Transmission Somatodendritic Compartment Regulation Of Postsynaptic Membrane Potential Monoatomic Ion Transport Lysosomal Transport Inorganic Cation Transmembrane Transport Early Endosome To Late Endosome Transport Monoatomic Cation Transmembrane Transport AMPA Glutamate Receptor Complex Dynein Light Intermediate Chain Binding Positive Regulation Of Synaptic Transmission Late Endosome Protein Localization To Postsynaptic Membrane Positive Regulation Of Excitatory Postsynaptic Potential Inorganic Ion Transmembrane Transport Protein Localization To Postsynapse Transmembrane Transport Monoatomic Ion Channel Activity Vacuolar Transport Monoatomic Cation Transport Trans-Golgi Network Mitotic Cleavage Furrow Ingression Pigment Granule Maturation Peptide Pheromone Maturation Chaperone-mediated Autophagy Translocation Complex Establishment Of Protein Localization
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