FRS2 and CBL

  • Number of citations of the paper that reports this interaction (PMID 11997436)
  • 29
  • Data Source:
  • HPRD (in vitro)

FRS2

CBL

Gene Name fibroblast growth factor receptor substrate 2 Cbl proto-oncogene, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 22 interactors: CBL CRK DDR1 FGFR1 GAB1 GRB2 INSR KDR MAPK1 NCK1 NTRK1 NTRK2 NTRK3 PAK1 PRKCI PRKCZ PTPN11 PTPRF RET RND1 SOS1 SRC 114 interactors: ABL1 ASAP1 AXL BCR BLK BLNK BTK CAPN1 CD19 CD2AP CD38 CD40 CD5 CDKL2 CRK CRKL CSF1R CTNNB1 CUBN EGFR EIF5B EPHA2 EPHB6 EPOR ERBB2 F2RL1 FGR FLOT1 FLT3 FNBP1 FRS2 FYB FYN GIF GRB2 HCK IGF1R INPPL1 INSR ITCH ITK ITSN2 KDR KHDRBS1 KIT KRT18 LAT LAT2 LCK LCP2 LRIG1 LTK LYN MAPK8 MET MYH9 MYO1C NCK1 NOTCH1 OSTF1 PDGFRA PDGFRB PIK3R1 PIK3R2 PLCG1 PRKCA PRKCQ PTK2B PTPN11 PTPN22 PTPN6 RET SCN5A SH2B2 SH3KBP1 SHC1 SLA SLA2 SORBS1 SORBS2 SPRY2 SRC STAP2 STAT5A STAT5B SYK TCN1 TCN2 TGFBR2 TNFRSF11A TNS4 TRAF4 TRAF6 TRIM8 TYK2 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2G2 UBE2L3 UBE2M USP21 VAV1 VAV2 YES1 YWHAB YWHAG YWHAQ YWHAZ ZAP70
Entrez ID 10818 867
HPRD ID 06372 01320
Ensembl ID ENSG00000166225 ENSG00000110395
Uniprot IDs L7RTG7 Q8WU20 P22681
PDB IDs 1XR0 1B47 1FBV 1YVH 2CBL 2JUJ 2K4D 2OO9 2Y1M 2Y1N 3BUM 3BUN 3BUO 3BUW 3BUX 3OB1 3OB2 3PLF 4A49 4A4B 4A4C 4GPL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adapter  adenoviruses  bdnf  branching  cascades  cortical  docking  facilitates  fgf  frs3  gab1  gab2  goals  grb2  impairs  multiprotein  neurite  neurotrophic  neurotrophin  neurotrophins  outgrowth  phosphatidylinositide  pi3  route  shp2  stimulates  trk  twofold  utilize 
32dcl3  32p  antisera  eliminated  engagement  fusion  fyn  gst  hck  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
Tagcloud (Difference) ?
adapter  adenoviruses  bdnf  branching  cascades  cortical  docking  facilitates  fgf  frs3  gab1  gab2  goals  grb2  impairs  multiprotein  neurite  neurotrophic  neurotrophin  neurotrophins  outgrowth  phosphatidylinositide  pi3  route  shp2  stimulates  trk  twofold  utilize 
32dcl3  32p  antisera  eliminated  engagement  fusion  fyn  gst  hck  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
Tagcloud (Intersection) ?