FRS2 and INSR

  • Number of citations of the paper that reports this interaction (PMID 10650943)
  • 7
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

FRS2

INSR

Gene Name fibroblast growth factor receptor substrate 2 insulin receptor
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 22 interactors: CBL CRK DDR1 FGFR1 GAB1 GRB2 INSR KDR MAPK1 NCK1 NTRK1 NTRK2 NTRK3 PAK1 PRKCI PRKCZ PTPN11 PTPRF RET RND1 SOS1 SRC 77 interactors: ACP1 ADRB2 AHSG ARF1 ARHGAP26 CALM1 CALM2 CALM3 CAV1 CAV3 CBL CEACAM1 CRK CRKL CSK DOK1 DOK4 DOK5 ENPP1 FABP4 FRS2 GAB1 GNB2L1 GRB10 GRB14 GRB7 HRAS IGF1R IGF2 INS INSRR IRF7 IRS1 IRS2 JAK1 JAK2 KHDRBS1 KRT27 KRT31 MAD2L1 MAPK3 PIK3R1 PIK3R3 PLCG1 PRKCA PRKCD PTK2 PTPN1 PTPN11 PTPN12 PTPN2 PTPN6 PTPRC PTPRF RAF1 RASA1 SH2B1 SH2B2 SHC1 SMAD2 SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS2 SOCS3 SOCS6 SORBS1 SRC STAT5A STAT5B SYNCRIP TEAD1 VAV1 VAV3 YWHAB
Entrez ID 10818 3643
HPRD ID 06372 00975
Ensembl ID ENSG00000166225 ENSG00000171105
Uniprot IDs L7RTG7 Q8WU20 P06213
PDB IDs 1XR0 1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA 3LOH 3W11 3W12 3W13 3W14 4IBM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adapter  adenoviruses  bdnf  branching  cascades  cortical  docking  facilitates  fgf  frs3  gab1  gab2  goals  grb2  impairs  multiprotein  neurite  neurotrophic  neurotrophin  neurotrophins  outgrowth  phosphatidylinositide  pi3  route  shp2  stimulates  trk  twofold  utilize 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Difference) ?
adapter  adenoviruses  bdnf  branching  cascades  cortical  docking  facilitates  fgf  frs3  gab1  gab2  goals  grb2  impairs  multiprotein  neurite  neurotrophic  neurotrophin  neurotrophins  outgrowth  phosphatidylinositide  pi3  route  shp2  stimulates  trk  twofold  utilize 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Intersection) ?