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NDRG1 and AP1M2
Number of citations of the paper that reports this interaction (PubMedID
17220478
)
0
Data Source:
HPRD
(in vivo)
NDRG1
AP1M2
Description
N-myc downstream regulated 1
adaptor related protein complex 1 subunit mu 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Microtubule
Plasma Membrane
Adherens Junction
Microtubule Cytoskeleton
Membrane
Perinuclear Region Of Cytoplasm
Recycling Endosome Membrane
Extracellular Exosome
Golgi Membrane
Lysosomal Membrane
Golgi Apparatus
Cytosol
Membrane
AP-1 Adaptor Complex
Clathrin Adaptor Complex
Clathrin-coated Vesicle
Cytoplasmic Vesicle Membrane
Clathrin-coated Vesicle Membrane
Cytoplasmic Vesicle
Trans-Golgi Network Membrane
Molecular Function
Protein Binding
Microtubule Binding
Nickel Cation Binding
Small GTPase Binding
Gamma-tubulin Binding
Cadherin Binding
Protein Binding
Clathrin Adaptor Activity
Biological Process
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Response To Metal Ion
DNA Damage Response, Signal Transduction By P53 Class Mediator
Peripheral Nervous System Myelin Maintenance
Mast Cell Activation
Cellular Response To Hypoxia
Protein Targeting
Intracellular Protein Transport
Vesicle Targeting
Protein Transport
Vesicle-mediated Transport
Establishment Of Protein Localization
Establishment Of Localization In Cell
Basolateral Protein Secretion
Pathways
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
Nef mediated downregulation of MHC class I complex cell surface expression
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Estimated glomerular filtration rate (
31015462
)
Left-handedness (
32989287
)
Nontyphoidal Salmonella bacteraemia (
29523850
)
Post-traumatic stress disorder (asjusted for relatedness) (
23726511
)
Bipolar disorder (
31043756
)
Lymphocyte percentage of white cells (
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Platelet count (
27863252
)
Plateletcrit (
27863252
32888494
)
Red cell distribution width (
27863252
28957414
32888494
)
Interacting Genes
71 interacting genes:
ACSL3
ACTG1
AP1M2
AP2M1
APOA1
APOA2
ARL4D
ATP1A1
CANX
CDH1
CLTC
CNDP2
COPB2
CTNNB1
DDX1
DDX5
DLST
EEF1G
EEF2
EIF2S3
EIF3E
ETS2
EWSR1
FASN
GSK3B
HNRNPF
HNRNPH1
HNRNPU
HSD17B4
HSP90AA1
HSPA5
ILF3
KIF5B
LDHA
MAOA
MLH1
MME
MYC
NCL
NR4A1
PABPC1
PHYHIP
PKM
PPP2R2A
PRKACA
PSMC2
PSMC3
PSMD2
RPL24
RPL3
RPL4
RPN2
RPS16
RPS20
RPS26
RPS3
RPS6
RPS8
RTN1
RUVBL2
S100B
SEC23A
SGK1
SHMT2
TAF9
TARS1
TLE3
UPF1
VCP
XRCC5
ZNF155
20 interacting genes:
A2M
AP1B1
AP1G1
AP1M1
AP1S1
AP2B1
APP
BLMH
ECSIT
EHD2
GAK
LDLR
LOXL4
MAST1
NDRG1
PSEN1
PVR
RAB3A
RAB3D
TGOLN2
Entrez ID
10397
10053
HPRD ID
05586
06296
Ensembl ID
ENSG00000104419
ENSG00000129354
Uniprot IDs
Q8N959
Q92597
Q53GI5
Q9Y6Q5
PDB IDs
6ZMM
Enriched GO Terms of Interacting Partners
?
Ribonucleoprotein Complex
Extracellular Exosome
Cytosol
RNA Binding
Macromolecule Metabolic Process
Translation
Cytosolic Ribosome
Macromolecule Biosynthetic Process
Cadherin Binding
Response To Cytokine
Protein Metabolic Process
Response To Peptide
Secretory Granule Lumen
Cellular Response To Cytokine Stimulus
Cytoplasmic Translation
Membrane
Nucleoplasm
ATP Hydrolysis Activity
Regulation Of Protein Metabolic Process
Ribosome
Nucleobase-containing Compound Metabolic Process
Cytosolic Small Ribosomal Subunit
Structural Constituent Of Ribosome
Regulation Of Primary Metabolic Process
Small Ribosomal Subunit
Nucleotide Binding
Protein-RNA Complex Assembly
Regulation Of Translation
ATP Binding
Nucleic Acid Metabolic Process
Regulation Of Telomere Maintenance
Protein Binding
Catabolic Process
RNA Metabolic Process
Positive Regulation Of Cytoplasmic Translation
Ficolin-1-rich Granule Lumen
Protein-containing Complex Organization
Regulation Of RNA Splicing
Macromolecule Catabolic Process
Cytoplasm
Focal Adhesion
Positive Regulation Of Biosynthetic Process
Nucleus
Plasma Lipoprotein Particle Assembly
Protein-lipid Complex Assembly
Disordered Domain Specific Binding
Regulation Of Macromolecule Metabolic Process
Ubiquitin Protein Ligase Binding
Regulation Of Metabolic Process
Post-transcriptional Regulation Of Gene Expression
AP-1 Adaptor Complex
Early Endosome
Melanosome Assembly
Clathrin Adaptor Activity
Basolateral Protein Secretion
Platelet Dense Granule Organization
Clathrin-coated Pit
Vesicle-mediated Transport
Membrane Coat
Melanosome Organization
Pigment Granule Organization
Trans-Golgi Network Membrane
Cytoplasmic Vesicle
Clathrin Adaptor Complex
Import Into Cell
Intracellular Transport
Establishment Of Localization In Cell
Synaptic Vesicle
Endocytosis
Secretory Granule Organization
Regulation Of Amyloid Fibril Formation
GTP-dependent Protein Binding
Regulation Of Vesicle-mediated Transport
Cellular Localization
Lysosomal Membrane
Secretion By Cell
Presynapse
Astrocyte Activation Involved In Immune Response
Clathrin Binding
Clathrin-coated Vesicle Membrane
Golgi Apparatus
Protein Localization To Extracellular Region
Protein Secretion
Establishment Of Protein Localization To Extracellular Region
Positive Regulation Of Amyloid Fibril Formation
Growth Factor Receptor Binding
Intracellular Protein Localization
Endosome
Protein Transport
Secretion
Positive Regulation Of Regulated Secretory Pathway
Vesicle Organization
Positive Regulation Of Transport
Cytoplasmic Vesicle Membrane
Receptor-mediated Endocytosis
Endosome To Melanosome Transport
Establishment Of Protein Localization
Golgi To Lysosome Transport
Clathrin-coated Endocytic Vesicle Membrane
Clathrin-coated Vesicle
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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