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AP1M2 and AP2B1
Number of citations of the paper that reports this interaction (PubMedID
12086608
)
0
Data Source:
HPRD
(in vitro)
AP1M2
AP2B1
Description
adaptor related protein complex 1 subunit mu 2
adaptor related protein complex 2 subunit beta 1
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Lysosomal Membrane
Golgi Apparatus
Cytosol
Membrane
AP-1 Adaptor Complex
Clathrin Adaptor Complex
Clathrin-coated Vesicle
Cytoplasmic Vesicle Membrane
Clathrin-coated Vesicle Membrane
Cytoplasmic Vesicle
Trans-Golgi Network Membrane
Lysosomal Membrane
Cytosol
Plasma Membrane
Clathrin-coated Pit
Synaptic Vesicle
Cytoplasmic Side Of Plasma Membrane
Endomembrane System
Membrane
Membrane Coat
Clathrin Coat
AP-2 Adaptor Complex
Clathrin Adaptor Complex
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Endolysosome Membrane
Synapse
Clathrin-coated Endocytic Vesicle
Postsynaptic Endocytic Zone
Extrinsic Component Of Presynaptic Endocytic Zone Membrane
Glutamatergic Synapse
Molecular Function
Protein Binding
Clathrin Adaptor Activity
Signal Sequence Binding
Protein Binding
Clathrin Binding
Clathrin Adaptor Activity
Protein-containing Complex Binding
Biological Process
Protein Targeting
Intracellular Protein Transport
Vesicle Targeting
Protein Transport
Vesicle-mediated Transport
Establishment Of Protein Localization
Establishment Of Localization In Cell
Basolateral Protein Secretion
Kidney Development
Cardiac Septum Development
Ventricular Septum Development
Intracellular Protein Transport
Endocytosis
Chemical Synaptic Transmission
Neurotransmitter Secretion
Heart Development
Protein Transport
Vesicle-mediated Transport
Aorta Development
Positive Regulation Of Endocytosis
Clathrin Coat Assembly
Synaptic Vesicle Endocytosis
Coronary Vasculature Development
Clathrin-dependent Endocytosis
Postsynaptic Neurotransmitter Receptor Internalization
Positive Regulation Of Protein Localization To Membrane
Pathways
Nef mediated downregulation of MHC class I complex cell surface expression
MHC class II antigen presentation
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Nef Mediated CD4 Down-regulation
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Nef Mediated CD8 Down-regulation
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Lymphocyte percentage of white cells (
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Platelet count (
27863252
)
Plateletcrit (
27863252
32888494
)
Red cell distribution width (
27863252
28957414
32888494
)
Cerebrospinal AB1-42 levels in normal cognition (
29274321
)
Chronotype (
30696823
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Immature fraction of reticulocytes (
32888494
)
Mean platelet volume (
22139419
27863252
32888494
)
Mean reticulocyte volume (
32888494
)
Platelet count (
22139419
27863252
)
Platelet distribution width (
27863252
)
Reticulocyte count (
27863252
32888494
)
Reticulocyte fraction of red cells (
27863252
32888494
)
Interacting Genes
20 interacting genes:
A2M
AP1B1
AP1G1
AP1M1
AP1S1
AP2B1
APP
BLMH
ECSIT
EHD2
GAK
LDLR
LOXL4
MAST1
NDRG1
PSEN1
PVR
RAB3A
RAB3D
TGOLN2
60 interacting genes:
-
ACVR1
AFF4
AP1M1
AP1M2
AP2A2
AP2M1
AP2S1
APC
ARF6
ARRB1
ATM
ATP23
ATP6V1G1
BUB1
BUB1B
CATSPERT
CCDC187
CEBPA
CLINT1
COL3A1
DHX58
DNAJC5
DSCAM
FMNL2
GPANK1
GTF2I
HIP1
HPCA
HSPB1
KANK2
KIAA0408
KPNA2
LDLRAP1
LONRF1
MEA1
MLH1
NECAP2
NEU4
NUP54
PIP5K1C
POM121
PSORS1C2
RAPGEF3
RIBC2
SLC25A6
SLC2A8
SMAD4
SMURF1
SNAP91
TENT5C
TERF2IP
TEX12
TGFBR1
TGFBR2
THAP1
TUBGCP4
TXN2
U2AF1
UBC
Entrez ID
10053
163
HPRD ID
06296
03015
Ensembl ID
ENSG00000129354
ENSG00000006125
Uniprot IDs
Q53GI5
Q9Y6Q5
A0A140VJE8
P63010
Q96EL6
PDB IDs
1E42
2G30
2IV8
2IV9
2JKR
2JKT
2VGL
2XA7
4UQI
5M5R
6QH5
6QH6
6QH7
6URI
6YAE
6YAF
6YAH
6YAI
7OG1
7OHO
7OM8
7Z5C
Enriched GO Terms of Interacting Partners
?
AP-1 Adaptor Complex
Early Endosome
Melanosome Assembly
Clathrin Adaptor Activity
Basolateral Protein Secretion
Platelet Dense Granule Organization
Clathrin-coated Pit
Vesicle-mediated Transport
Membrane Coat
Melanosome Organization
Pigment Granule Organization
Trans-Golgi Network Membrane
Cytoplasmic Vesicle
Clathrin Adaptor Complex
Import Into Cell
Intracellular Transport
Establishment Of Localization In Cell
Synaptic Vesicle
Endocytosis
Secretory Granule Organization
Regulation Of Amyloid Fibril Formation
GTP-dependent Protein Binding
Regulation Of Vesicle-mediated Transport
Cellular Localization
Lysosomal Membrane
Secretion By Cell
Presynapse
Astrocyte Activation Involved In Immune Response
Clathrin Binding
Clathrin-coated Vesicle Membrane
Golgi Apparatus
Protein Localization To Extracellular Region
Protein Secretion
Establishment Of Protein Localization To Extracellular Region
Positive Regulation Of Amyloid Fibril Formation
Growth Factor Receptor Binding
Intracellular Protein Localization
Endosome
Protein Transport
Secretion
Positive Regulation Of Regulated Secretory Pathway
Vesicle Organization
Positive Regulation Of Transport
Cytoplasmic Vesicle Membrane
Receptor-mediated Endocytosis
Endosome To Melanosome Transport
Establishment Of Protein Localization
Golgi To Lysosome Transport
Clathrin-coated Endocytic Vesicle Membrane
Clathrin-coated Vesicle
Clathrin Adaptor Activity
SMAD Binding
Clathrin Adaptor Complex
Clathrin-dependent Endocytosis
Clathrin-coated Pit
Synaptic Vesicle Endocytosis
Regulation Of Receptor-mediated Endocytosis
Presynaptic Endocytosis
Endocytosis
Clathrin Coat Assembly
Vesicle-mediated Transport In Synapse
Activin Receptor Complex
Activin Receptor Activity, Type I
Postsynaptic Neurotransmitter Receptor Internalization
Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition
Activin Receptor Signaling Pathway
Receptor-mediated Endocytosis
Mitotic Spindle Assembly Checkpoint Signaling
Intracellular Protein Transport
Clathrin-coated Endocytic Vesicle Membrane
Negative Regulation Of Mitotic Metaphase/anaphase Transition
Activin Binding
Endocytic Vesicle Membrane
AP-2 Adaptor Complex
Receptor Internalization
Clathrin-coated Vesicle Membrane
Clathrin Binding
Protein Transport
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Clathrin-coated Vesicle
Negative Regulation Of Chromosome Organization
Ventricular Septum Morphogenesis
Negative Regulation Of Mitotic Nuclear Division
Positive Regulation Of SMAD Protein Signal Transduction
Import Into Cell
Regulation Of Endocytosis
Vesicle-mediated Transport
I-SMAD Binding
Negative Regulation Of Mitotic Cell Cycle Phase Transition
DNA-dependent Protein Kinase Activity
Transforming Growth Factor Beta Ligand-receptor Complex
Transforming Growth Factor Beta Receptor Signaling Pathway
Endolysosome Membrane
Positive Regulation Of Receptor-mediated Endocytosis
Transforming Growth Factor Beta Binding
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Negative Regulation Of Cellular Component Organization
Establishment Of Protein Localization
Positive Regulation Of Cellular Component Organization
Intracellular Protein Localization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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