NDRG1 and RPN2

Number of citations of the paper that reports this interaction (PMID 17220478)
17

Data Source:
HPRD (in vivo)

		NDRG1	RPN2
Gene Name		N-myc downstream regulated 1	ribophorin II
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Microtubule Plasma Membrane Cell-cell Adherens Junction Microtubule Cytoskeleton Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Vesicular Exosome	Autophagic Vacuole Membrane Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Oligosaccharyltransferase Complex Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Microtubule Binding Rab GTPase Binding Gamma-tubulin Binding Cadherin Binding	Dolichyl-diphosphooligosaccharide-protein Glycotransferase Activity Ribosome Binding
	Biological Process	Response To Metal Ion DNA Damage Response, Signal Transduction By P53 Class Mediator Peripheral Nervous System Myelin Maintenance Mast Cell Activation Cellular Response To Hypoxia Positive Regulation Of Spindle Checkpoint	Translation Cellular Protein Modification Process SRP-dependent Cotranslational Protein Targeting To Membrane Aging Gene Expression Protein N-linked Glycosylation Via Asparagine Response To Drug Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Translation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification SRP-dependent cotranslational protein targeting to membrane Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective MOGS causes MOGS-CDG (CDG-2b) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Defective ALG11 causes ALG11-CDG (CDG-1p)
Drugs
Diseases
GWAS		Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)	Hippocampal atrophy ( 19668339)
Protein-Protein Interactions		64 interactors: ACSL3 ACTG1 AP1M2 AP2M1 ARL4D ATP1A1 CANX CDH1 CLTC CNDP2 COPB2 CTNNB1 DDX1 DDX5 DLST EEF1G EEF2 EIF2S3 EIF3E EWSR1 FASN HNRNPF HNRNPH1 HNRNPU HSD17B4 HSP90AA1 HSPA5 ILF3 KIF5B LDHA MAOA MLH1 MME NCL PABPC1 PHYHIP PKM PPP2R2A PRKACA PSMC2 PSMC3 PSMD2 RPL24 RPL3 RPL4 RPN2 RPS16 RPS20 RPS26 RPS3 RPS6 RPS8 RUVBL2 S100B SEC23A SGK1 SHMT2 TAF9 TARS TLE3 UPF1 VCP XRCC5 ZNF155	8 interactors: ADRM1 EZH2 FBN3 NDRG1 NGFR RBBP4 RCHY1 RHOA
Entrez ID		10397	6185
HPRD ID		05586	01609
Ensembl ID		ENSG00000104419	ENSG00000118705
Uniprot IDs		Q8N959 Q92597	P04844
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process MRNA Metabolic Process Gene Expression Cellular Metabolic Process Cellular Macromolecule Catabolic Process Membrane Organization Protein Localization To Endoplasmic Reticulum SRP-dependent Cotranslational Protein Targeting To Membrane Catabolic Process Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Aromatic Compound Catabolic Process Viral Process Translational Initiation Establishment Of Protein Localization To Membrane Translational Elongation Cellular Nitrogen Compound Metabolic Process Viral Transcription Translation Nitrogen Compound Metabolic Process Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Targeting To Membrane Biosynthetic Process Establishment Of Protein Localization Intracellular Protein Transport Establishment Of Protein Localization To Organelle Translational Termination Protein Localization Protein Localization To Membrane Protein Localization To Organelle Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Protein Targeting Macromolecule Biosynthetic Process Protein Transport Cellular Protein Complex Disassembly RNA Metabolic Process Viral Life Cycle Cytoplasmic Transport Protein Complex Disassembly Intracellular Transport Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process	Regulation Of Cell Cycle Positive Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Axonogenesis Regulation Of Epidermis Development Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Axonogenesis Regulation Of Cell Morphogenesis Regulation Of Cell Cycle Process Positive Regulation Of Cell Development Negative Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Neurogenesis Regulation Of Proteolysis Negative Regulation Of Cell Projection Organization Regulation Of Neurogenesis Negative Regulation Of Hair Follicle Development Skeletal Muscle Satellite Cell Migration Regulation Of Axonogenesis Negative Regulation Of Cell Differentiation Negative Regulation Of Hair Cycle Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Neuron Differentiation Regulation Of Cell Development Positive Regulation Of Cell Differentiation Regulation Of Gene Expression, Epigenetic Neurotrophin TRK Receptor Signaling Pathway Apolipoprotein A-I-mediated Signaling Pathway Positive Regulation Of Neuron Projection Development Positive Regulation Of Cell Cycle Process Neurotrophin Signaling Pathway Positive Regulation Of Spindle Checkpoint Cleavage Furrow Formation Regulation Of Protein Metabolic Process Central Nervous System Development Nervous System Development G1 To G0 Transition Protein Complex Assembly Cell Cycle Process DNA Replication-dependent Nucleosome Assembly Positive Regulation Of Cell Projection Organization Positive Regulation Of Cell Cycle Negative Regulation Of Epidermal Cell Differentiation Positive Regulation Of Cell Cycle Checkpoint Proteasome Assembly Histone H3-K27 Methylation Negative Regulation Of Neurogenesis Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		4ebp1 allosteric bid dosing dysregulated es ewing integrates liposarcoma master mln0128 mtorc1 mtorc2 osteosarcoma pakt pan promise rapalogues rapamycin reactivation rhabdomyosarcoma rms sarcoma schedule schedules sheath striking synovial tiw	acc1 adp1 aids albicans antiretroviral candida candidiasis decades diploid divergence epidemiology fluconazole gln4 haart heterozygous immunocompromised iran iranian isolate loci mlst multilocus phylogeny polymorphic scheme sya1 typed typing vps13
Tagcloud (Difference) ?		4ebp1 allosteric bid dosing dysregulated es ewing integrates liposarcoma master mln0128 mtorc1 mtorc2 osteosarcoma pakt pan promise rapalogues rapamycin reactivation rhabdomyosarcoma rms sarcoma schedule schedules sheath striking synovial tiw	acc1 adp1 aids albicans antiretroviral candida candidiasis decades diploid divergence epidemiology fluconazole gln4 haart heterozygous immunocompromised iran iranian isolate loci mlst multilocus phylogeny polymorphic scheme sya1 typed typing vps13
Tagcloud (Intersection) ?