AP1M2

Gene Name		adaptor-related protein complex 1, mu 2 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function
	Biological Process	Protein Targeting Post-Golgi Vesicle-mediated Transport Vesicle Targeting Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		20 interactors: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2
Entrez ID		10053
HPRD ID		06296
Ensembl ID		ENSG00000129354
Uniprot IDs		Q9Y6Q5
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Regulation Of Defense Response To Virus By Virus Establishment Of Localization In Cell Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Endocytosis Antigen Processing And Presentation Of Peptide Antigen Cellular Localization Intracellular Transport Antigen Processing And Presentation Viral Process Intracellular Protein Transport Cellular Protein Localization Protein Transport Protein Localization Positive Regulation Of Regulated Secretory Pathway Establishment Of Protein Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Post-Golgi Vesicle-mediated Transport Transport Immune System Process Regulation Of Immune System Process Response To External Stimulus Regulation Of Regulated Secretory Pathway Exocytosis Receptor-mediated Endocytosis Synaptic Vesicle Exocytosis Response To Stimulus Positive Regulation Of Exocytosis Endosome To Melanosome Transport Pigment Granule Maturation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Pigment Accumulation Regulation Of ERBB Signaling Pathway Membrane Organization Secretion By Cell Golgi Vesicle Transport Neurotransmitter Secretion Synaptic Vesicle Transport Cell Differentiation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Establishment Of Organelle Localization Secretion Positive Regulation Of Natural Killer Cell Mediated Immunity Melanosome Organization Pigment Granule Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Neurotransmitter Levels
Tagcloud ?		acaa1 analogous aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine