NDRG1 and ARL4D

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NDRG1	ARL4D
Description		N-myc downstream regulated 1	ARF like GTPase 4D
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule Plasma Membrane Adherens Junction Microtubule Cytoskeleton Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome	Nucleus Nucleolus Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding Microtubule Binding Nickel Cation Binding Small GTPase Binding Gamma-tubulin Binding Cadherin Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Metal Ion DNA Damage Response, Signal Transduction By P53 Class Mediator Peripheral Nervous System Myelin Maintenance Mast Cell Activation Cellular Response To Hypoxia	Intracellular Protein Transport Protein Secretion Vesicle-mediated Transport
Pathways		TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Estimated glomerular filtration rate ( 31015462) Left-handedness ( 32989287) Nontyphoidal Salmonella bacteraemia ( 29523850) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
Interacting Genes		71 interacting genes: ACSL3 ACTG1 AP1M2 AP2M1 APOA1 APOA2 ARL4D ATP1A1 CANX CDH1 CLTC CNDP2 COPB2 CTNNB1 DDX1 DDX5 DLST EEF1G EEF2 EIF2S3 EIF3E ETS2 EWSR1 FASN GSK3B HNRNPF HNRNPH1 HNRNPU HSD17B4 HSP90AA1 HSPA5 ILF3 KIF5B LDHA MAOA MLH1 MME MYC NCL NR4A1 PABPC1 PHYHIP PKM PPP2R2A PRKACA PSMC2 PSMC3 PSMD2 RPL24 RPL3 RPL4 RPN2 RPS16 RPS20 RPS26 RPS3 RPS6 RPS8 RTN1 RUVBL2 S100B SEC23A SGK1 SHMT2 TAF9 TARS1 TLE3 UPF1 VCP XRCC5 ZNF155	22 interacting genes: APP ARL6IP1 CCDC102B CNPY4 CYTH2 DNAJA1 EIF2B1 EML4 EPRS1 MAPK8IP3 NDRG1 PGAM1 PRKCSH SMAD1 SMAD2 SMURF1 SNRPN TGFBR1 TLE1 TMEM230 UBR1 UNC119
Entrez ID		10397	379
HPRD ID		05586	02842
Ensembl ID		ENSG00000104419	ENSG00000175906
Uniprot IDs		Q8N959 Q92597	P49703
PDB IDs		6ZMM
Enriched GO Terms of Interacting Partners?		Ribonucleoprotein Complex Extracellular Exosome Cytosol RNA Binding Macromolecule Metabolic Process Translation Cytosolic Ribosome Macromolecule Biosynthetic Process Cadherin Binding Response To Cytokine Protein Metabolic Process Response To Peptide Secretory Granule Lumen Cellular Response To Cytokine Stimulus Cytoplasmic Translation Membrane Nucleoplasm ATP Hydrolysis Activity Regulation Of Protein Metabolic Process Ribosome Nucleobase-containing Compound Metabolic Process Cytosolic Small Ribosomal Subunit Structural Constituent Of Ribosome Regulation Of Primary Metabolic Process Small Ribosomal Subunit Nucleotide Binding Protein-RNA Complex Assembly Regulation Of Translation ATP Binding Nucleic Acid Metabolic Process Regulation Of Telomere Maintenance Protein Binding Catabolic Process RNA Metabolic Process Positive Regulation Of Cytoplasmic Translation Ficolin-1-rich Granule Lumen Protein-containing Complex Organization Regulation Of RNA Splicing Macromolecule Catabolic Process Cytoplasm Focal Adhesion Positive Regulation Of Biosynthetic Process Nucleus Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Disordered Domain Specific Binding Regulation Of Macromolecule Metabolic Process Ubiquitin Protein Ligase Binding Regulation Of Metabolic Process Post-transcriptional Regulation Of Gene Expression	I-SMAD Binding Homomeric SMAD Protein Complex SMAD Protein Complex SMAD Binding Trophoblast Cell Migration Heteromeric SMAD Protein Complex Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Co-SMAD Binding Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Primary MiRNA Processing Axo-dendritic Transport Transforming Growth Factor Beta Receptor Binding Transforming Growth Factor Beta Receptor Signaling Pathway Low-density Lipoprotein Particle Receptor Binding Response To Growth Factor Protein Serine/threonine Kinase Binding Cytosol Cytoplasm Ubiquitin Protein Ligase Binding SMAD Protein Signal Transduction Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway Response To Cholesterol R-SMAD Binding Growth Cone Regulation Of JNK Cascade MiRNA Processing Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Proline-tRNA Ligase Activity Prolyl-tRNA Aminoacylation Ureteric Bud Development Engulfment Of Target By Autophagosome Transport Along Microtubule
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