AP1M2 and BLMH

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		AP1M2	BLMH
Gene Name		adaptor-related protein complex 1, mu 2 subunit	bleomycin hydrolase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome
	Molecular Function		Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Protein Targeting Post-Golgi Vesicle-mediated Transport Vesicle Targeting Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Membrane Organization	Protein Polyubiquitination Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Proteolysis Response To Toxic Substance Response To Drug
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: A2M AP1B1 AP1G1 AP1M1 AP1S1 AP2B1 APP BLMH ECSIT EHD2 GAK LDLR LOXL4 MAST1 NDRG1 PSEN1 PVR RAB3A RAB3D TGOLN2	14 interactors: AP1M2 APP CYP2C8 ECSIT KBTBD7 MAST1 NUDT12 PDPK1 RNF32 RPL11 RPL29 TRIO UBE2I WDYHV1
Entrez ID		10053	642
HPRD ID		06296	03870
Ensembl ID		ENSG00000129354	ENSG00000108578
Uniprot IDs		Q9Y6Q5	E7EMN3 Q13867
PDB IDs			1CB5 2CB5
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Regulation Of Defense Response To Virus By Virus Establishment Of Localization In Cell Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Endocytosis Antigen Processing And Presentation Of Peptide Antigen Cellular Localization Intracellular Transport Antigen Processing And Presentation Viral Process Intracellular Protein Transport Cellular Protein Localization Protein Transport Protein Localization Positive Regulation Of Regulated Secretory Pathway Establishment Of Protein Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Post-Golgi Vesicle-mediated Transport Transport Immune System Process Regulation Of Immune System Process Response To External Stimulus Regulation Of Regulated Secretory Pathway Exocytosis Receptor-mediated Endocytosis Synaptic Vesicle Exocytosis Response To Stimulus Positive Regulation Of Exocytosis Endosome To Melanosome Transport Pigment Granule Maturation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Pigment Accumulation Regulation Of ERBB Signaling Pathway Membrane Organization Secretion By Cell Golgi Vesicle Transport Neurotransmitter Secretion Synaptic Vesicle Transport Cell Differentiation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Establishment Of Organelle Localization Secretion Positive Regulation Of Natural Killer Cell Mediated Immunity Melanosome Organization Pigment Granule Organization Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Neurotransmitter Levels	Viral Process NAD Catabolic Process Positive Regulation Of SUMO Transferase Activity Cellular Protein Metabolic Process Viral Transcription Axon Guidance Synaptic Growth At Neuromuscular Junction Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Protein Targeting Establishment Of Protein Localization To Endoplasmic Reticulum NADP Catabolic Process Collateral Sprouting In Absence Of Injury Aromatic Compound Catabolic Process Catabolic Process Regulation Of Receptor Activity Protein Localization To Endoplasmic Reticulum Axonogenesis Collateral Sprouting Axon Midline Choice Point Recognition Translational Termination MRNA Metabolic Process Nuclear-transcribed MRNA Catabolic Process Establishment Of Localization In Cell Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Development Protein Metabolic Process MRNA Catabolic Process Protein Targeting To Membrane Cell Morphogenesis Involved In Neuron Differentiation Locomotion Axon Choice Point Recognition Chemotaxis Translational Elongation Cellular Protein Modification Process RNA Catabolic Process Protein Phosphorylation Neuron Projection Morphogenesis Cellular Protein Complex Disassembly Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Omega-hydroxylase P450 Pathway Viral Life Cycle Cellular Protein Localization Platelet Activation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Neuron Remodeling Protein Complex Disassembly
Tagcloud ?		acaa1 analogous aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine	17q11 accn1 addressing amiloride bleomycin breakpoint breakpoints centromeric contig correctly deletions disabilities dysmorphism extending gross hydrolase mb mosaicism neurofibromatosis nf1 premise retardation smallest sro supt6h tagged telomerically yac yacs
Tagcloud (Difference) ?		acaa1 analogous aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p2rx4 p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine	17q11 accn1 addressing amiloride bleomycin breakpoint breakpoints centromeric contig correctly deletions disabilities dysmorphism extending gross hydrolase mb mosaicism neurofibromatosis nf1 premise retardation smallest sro supt6h tagged telomerically yac yacs
Tagcloud (Intersection) ?