CWF19L2 and VPS52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CWF19L2	VPS52
Description		CWF19 like cell cycle control factor 2	VPS52 subunit of GARP complex
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Post-mRNA Release Spliceosomal Complex	GARP Complex Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Presynapse Postsynapse EARP Complex
	Molecular Function	Protein Binding	Protein Binding Syntaxin Binding
	Biological Process	MRNA Splicing, Via Spliceosome	Protein Targeting Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development Vesicle-mediated Cholesterol Transport
Pathways		mRNA Splicing - Major Pathway	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Coronary artery disease ( 29212778) Cortex volume ( 31530798) Diastolic blood pressure ( 27841878) Fourth ventricle volume ( 31530798) Parkinson's disease progression (cognitive) ( 33111402) Pars opercularis volume ( 31530798) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		80 interacting genes: ABLIM3 APP AXIN2 BACH2 BRCA1 CALCOCO1 CALCOCO2 CARD10 CARD9 CCDC102B CCDC136 CCDC57 CCDC88B CEP63 CEP70 CEP76 CFAP53 CNTROB CWF19L1 DES DISC1 DRC4 EXOC8 FAM9B FCHO1 FSD2 FXR1 FXR2 GFAP GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOOK1 HOOK2 HSF2BP IKBKG IKZF1 KANK2 KASH5 KIF24 KIFC3 KRT40 LHX3 LHX9 LIMS1 LMNA LZTS1 LZTS2 M1AP MAD1L1 MEOX1 MTUS2 NAB2 NDEL1 PDE4DIP PIBF1 PICK1 PSTPIP1 RINT1 SF3B4 SNW1 STX11 TAX1BP1 TBC1D1 TFIP11 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM37 TRIM54 TRIM9 VIM VPS52 ZBTB8A ZMYND12 ZNF35 ZNF655 ZRANB1	101 interacting genes: AAMP AIRIM ARNT2 ATP6V1D BYSL C1orf216 CABP5 CACNA1A CATSPERT CCDC102B CCDC13 CCDC146 CCDC185 CCDC187 CCDC33 CCDC57 CCHCR1 CDC20B CDC5L CDK18 CEP19 CFAP206 CWF19L2 DCX DDX6 DNAJC11 DTNB EPM2AIP1 FAM110A FAM161A FAM161B FAM184A FAM50B GEM GFM2 GOLGA1 GORASP2 GPKOW HAUS1 HDAC4 HEATR1 HGS HOXB5 JAKMIP2 KANK2 KIAA1217 KIF5B KIF9 KIFC3 KLC3 KLHL42 LMO4 LNX1 MAGEL2 MAPK3 METTL13 MFAP1 MRPL1 MRPL11 NDC80 NFKBIB NOP2 NR2C2AP OTUD6A PIMREG PKN3 PPP1R18 PRKAA1 PRKAA2 RAB4A RAB4B RABEP2 RUNX1T1 SCNM1 SH2D4A SMARCE1 STX11 TAB2 TBC1D1 TBC1D22B TCEANC TCP11L1 TEAD4 THAP11 TPM3 TRAF4 TRAF6 TSSK3 TSTD2 TXLNB TXN2 USP2 VEZF1 VPS28 VPS53 WASHC3 WTAP ZC2HC1C ZMAT2 ZNF417 ZNF587
Entrez ID		143884	6293
HPRD ID		13102	09142
Ensembl ID		ENSG00000152404	ENSG00000223501
Uniprot IDs		Q2TBE0	A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4
PDB IDs		6ID0 6ID1 8RO2
Enriched GO Terms of Interacting Partners?		Cytoplasm Cytoskeleton Microtubule-based Process Identical Protein Binding Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Centrosome Protein Binding Microtubule Binding Microtubule Organizing Center Microtubule Supramolecular Fiber Organization Microtubule Organizing Center Organization Perinuclear Region Of Cytoplasm Organelle Assembly Cellular Component Assembly Centriole Intracellular Transport Cytosol Cellular Localization Establishment Of Localization In Cell Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Protein Domain Specific Binding Regulation Of Cellular Component Organization Regulation Of Organelle Organization Positive Regulation Of Gene Expression Plasma Membrane Bounded Cell Projection Organization Centriole Replication Regulation Of Centriole Replication Nuclear Pore Localization CBM Complex FHF Complex Regulation Of Long-term Neuronal Synaptic Plasticity Glial Cell Development Negative Regulation Of Cell Cycle Cytoplasmic Microtubule Organization Cilium Assembly Dynein Light Intermediate Chain Binding Negative Regulation Of Cell Cycle Process Membraneless Organelle Assembly Radial Glia-guided Pyramidal Neuron Migration Regulation Of Autophagy Microtubule Nucleation Centriole Assembly Regulation Of Synaptic Plasticity Intermediate Filament Organization	Protein Binding Cytoskeleton Organelle Assembly Centrosome Microtubule Binding Microtubule-based Process Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Organelle Organization Organelle Disassembly Ciliary Basal Body Kinesin Complex Protein Localization To Lipid Droplet Protein Localization To Vacuole Microtubule Cytoskeleton Organization Protein Localization To Lysosome Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Insulin-responsive Compartment Centriole
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