CWF19L2 and TP53BP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CWF19L2	TP53BP2
Gene Name		CWF19-like 2, cell cycle control (S. pombe)	tumor protein p53 binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Catalytic Activity	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Identical Protein Binding NF-kappaB Binding
	Biological Process	Metabolic Process	Cell Cycle Signal Transduction Central Nervous System Development Heart Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Signal Transduction Response To Ionizing Radiation Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: APP BRCA1 CALCOCO1 CALCOCO2 CARD9 CCDC136 CCDC57 FAM9B HOOK2 KRT40 LHX9 LZTS2 MAD1L1 MEOX1 MTUS2 NAB2 NDEL1 RINT1 SF3B4 STX11 TAX1BP1 TP53BP2 TRIM27 TRIM37 TRIM54 TRIM9 VIM	58 interactors: APP ATPAF2 ATXN7 BAIAP2 BCL2 BCL2L1 CCDC92 CSNK2B CWF19L2 DCUN1D1 EEF1A1 GRB2 HIST1H2BC HNRNPUL1 KIF5A LMO4 MAGI1 MAPK8IP2 MRPL20 MTMR14 NAE1 NDC80 NUTM1 OTUB2 PLEKHN1 PLK1 POLR2L PPHLN1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PTN RELA SIAH1 SIAH2 SSX2IP SUMO2 SUMO3 TANK TBC1D22B TCL1A TP53 TRAF4 TXLNA UBASH3A UNC119 USP4 UTP14A WWP1 WWP2 YAP1 YES1 YWHAG YWHAQ ZGPAT ZNF26
Entrez ID		143884	7159
HPRD ID		13102	11803
Ensembl ID		ENSG00000152404	ENSG00000143514
Uniprot IDs		Q2TBE0	Q13625
PDB IDs			1YCS 2UWQ 4A63
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Centriole Replication Intracellular Receptor Signaling Pathway Regulation Of Centriole Replication Regulation Of Cell Cycle Process Innate Immune Response Negative Regulation Of Centrosome Duplication Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Cellular Component Organization Regulation Of Transcription From RNA Polymerase III Promoter Establishment Of Localization In Cell Intracellular Transport Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cellular Process Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process Microtubule-based Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Negative Regulation Of Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Centrosome Duplication Protein Autoubiquitination Establishment Of Vesicle Localization Immune Response Cellular Localization Vesicle Localization Regulation Of Centrosome Cycle Axon Cargo Transport Centrosome Cycle Cell Cycle Defense Response Gonad Morphogenesis Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Regulation Of Metaphase Plate Congression Regulation Of Cytoskeleton Organization Secretion By Cell Organelle Organization Synaptic Vesicle Exocytosis Regulation Of Cytokine Production Vesicle-mediated Transport Cellular Process Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Gene Expression	Neuron Death Neuron Apoptotic Process Response To Radiation Regulation Of Signal Transduction Regulation Of Signaling Response To External Stimulus Negative Regulation Of Signal Transduction Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Signaling Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Apoptotic Signaling Pathway Cell Part Morphogenesis Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Phosphorylation Response To Light Stimulus Protein Modification By Small Protein Conjugation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Cycle Neuron Projection Morphogenesis Regulation Of Mitochondrion Organization Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cell Projection Morphogenesis Axonogenesis Cellular Protein Modification Process Positive Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Cell Morphogenesis Regulation Of Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Regulation Of Cellular Protein Metabolic Process Response To Gamma Radiation Axon Development Regulation Of Extrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Generation Of Neurons Nervous System Development Cellular Response To Ionizing Radiation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Innate Immune Response Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Neuron Projection Development Neurogenesis Anatomical Structure Morphogenesis
Tagcloud ?			adenovirus angiotensin apoptosis array at2r bag3 bmp6 bmp7 bnipi cytokine downregulation du145 gadd45a hrk il6 il8 mapk microrna next numerous p44 pc r2 silence sirnas tnfsf10 trail transduced utilized
Tagcloud (Difference) ?			adenovirus angiotensin apoptosis array at2r bag3 bmp6 bmp7 bnipi cytokine downregulation du145 gadd45a hrk il6 il8 mapk microrna next numerous p44 pc r2 silence sirnas tnfsf10 trail transduced utilized
Tagcloud (Intersection) ?