GPRIN2 and DYNLL2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		GPRIN2	DYNLL2
Gene Name		G protein regulated inducer of neurite outgrowth 2	dynein, light chain, LC8-type 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Centrosome Cytosol Microtubule Plasma Membrane Membrane Myosin Complex Dynein Complex Primary Cilium Ciliary Tip
	Molecular Function	Protein Binding	Motor Activity Protein Binding Cytoskeletal Protein Binding
	Biological Process		Transport Apoptotic Process Organelle Organization Microtubule-based Process Synaptic Target Recognition Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Organelle biogenesis and maintenance MHC class II antigen presentation Programmed Cell Death Activation of BH3-only proteins Assembly of the primary cilium Intraflagellar transport Adaptive Immune System Intrinsic Pathway for Apoptosis Activation of BMF and translocation to mitochondria
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: BCAP31 DYNLL2 KRTAP10-3 KRTAP12-1 KRTAP4-12 KRTAP4-7 MDFI PLSCR1 SFN SPRY2 TRIP13 YWHAE	20 interactors: BCL2L11 BMF C12orf40 CCDC36 DLGAP1 DNAL4 DYNC1I1 EWSR1 GPHN GPRIN2 HMBOX1 HOMER3 MEOX2 MORN3 MYO5A PAK1 RASGRP3 SECISBP2L THAP10 XIAP
Entrez ID		9721	140735
HPRD ID		13804	06489
Ensembl ID
Uniprot IDs		O60269	Q96FJ2
PDB IDs			2XQQ 3P8M
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Signal Transduction Regulation Of Mitochondrion Organization Regulation Of Signal Transduction Apoptotic Process Regulation Of Intracellular Transport Programmed Cell Death Regulation Of Signaling Cell Death Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Catalytic Activity Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Protein Localization Apoptotic Signaling Pathway Intracellular Signal Transduction Regulation Of Endopeptidase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Localization Positive Regulation Of Organelle Organization Synaptic Target Recognition Regulation Of Peptidase Activity Cell Differentiation Regulation Of Protein Metabolic Process Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Heart Rate By Hormone Developmental Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Regulation Of Epidermal Cell Division Negative Regulation Of Protein Serine/threonine Kinase Activity Response To Stimulus Regulation Of Phosphorus Metabolic Process Cellular Response To Stress Regulation Of Proteolysis Positive Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Positive Regulation Of Transport Negative Regulation Of Protein Dephosphorylation	Positive Regulation Of Protein Homooligomerization Positive Regulation Of Protein Oligomerization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Release Of Cytochrome C From Mitochondria Synapse Organization Regulation Of Protein Oligomerization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Death Death Regulation Of Intracellular Signal Transduction Receptor Clustering Neuromuscular Junction Development Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Glycine Receptor Clustering Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Developmental Pigmentation Positive Regulation Of Cellular Component Biogenesis Apoptotic Signaling Pathway Protein Localization To Membrane Membrane Organization Positive Regulation Of Protein Linear Polyubiquitination Signaling Regulation Of Mitochondrion Organization Cellular Localization Positive Regulation Of Organelle Organization Cell Communication Vesicle Transport Along Actin Filament Establishment Of Synaptic Specificity At Neuromuscular Junction Endoplasmic Reticulum Localization Apoptotic Process Pigmentation Programmed Cell Death Apoptotic Process Involved In Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process By Virus Odontogenesis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Intracellular Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Fibroblast Apoptotic Process Somite Specification Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Thymocyte Apoptotic Process Anoikis Locomotion Involved In Locomotory Behavior Histone H3-T11 Phosphorylation
Tagcloud ?			associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynlrb1 dynlt1 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Difference) ?			associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynlrb1 dynlt1 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Intersection) ?