GPRIN2 and DYNLL2

Number of citations: 0 (PubMedID 16189514)
Data Source: HPRD (two hybrid)

		GPRIN2	DYNLL2
Name		G protein regulated inducer of neurite outgrowth 2	dynein light chain LC8-type 2
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Microtubule Associated Complex Plasma Membrane Cilium Postsynaptic Density Microtubule Cytoskeleton Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Scaffold Protein Binding
	Biological Process	Neuron Projection Development	Microtubule-based Process
Pathways		None	Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
GWAS		No GWAS studies recorded	Blood protein levels ( 30072576 )
Novel Interactors		3 novel interactors: ARHGAP22 MAPK8 WDFY4	8 novel interactors: C17orf67 CHMP5 F13A1 HSF5 KIF2B MSI2 PRKD3 STXBP4
Interacting Genes		27 interacting genes: ANKS1A BCAP31 CYSRT1 DYNLL1 DYNLL2 FRS3 HAPLN2 HTR4 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP4-12 KRTAP4-7 LNP1 MDFI OTX1 PLSCR1 RHOU SFN SPRY2 TRIM55 TRIM63 TRIP13 YWHAE	30 interacting genes: BMF C14orf119 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HOMER3 IHO1 MEOX2 MORN3 MYO5A OTUD6A PAK1 PKIA PKIG RASGRP3 REDIC1 SKAP1 SMCP SPAG8 THAP10 TPPP XIAP ZAR1
Entrez ID		9721	140735
HPRD ID		13804	06489
Ensembl ID		ENSG00000204175	ENSG00000264364
Uniprot IDs		O60269	Q96FJ2
PDB IDs		Not available	2XQQ 3P8M 4D07 7CNU
GO Terms Enriched among Interactors		Intermediate Filament Keratin Filament Positive Regulation Of Establishment Of Protein Localization Phosphoserine Residue Binding Protein Sequestering Activity Positive Regulation Of Intracellular Transport Identical Protein Binding Regulation Of Establishment Of Protein Localization Scaffold Protein Binding Microtubule Protein Localization To Endoplasmic Reticulum Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Intracellular Protein Transport	Microtubule Binding