GPRIN2 and KRTAP4-12

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GPRIN2	KRTAP4-12
Gene Name		G protein regulated inducer of neurite outgrowth 2	keratin associated protein 4-12
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Keratin Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: BCAP31 DYNLL2 KRTAP10-3 KRTAP12-1 KRTAP4-12 KRTAP4-7 MDFI PLSCR1 SFN SPRY2 TRIP13 YWHAE	107 interactors: ADAMTSL4 ALPP AQP1 ATG12 ATN1 BAHD1 BEX2 C10orf62 C19orf66 CATSPER1 CBX2 CCDC116 CCDC185 CCNK CDC42EP1 CHCHD3 CHIC2 CLDN2 CNNM3 CNTFR COL8A1 CRCT1 CREB5 CRY1 DBF4B DLK2 EIF4E2 FAM107A FAM27E3 FAM76B FBXL18 FBXW5 GLRX3 GNE GPATCH2L GPRIN2 GRAP2 HHEX HOXA1 HOXB9 IFI30 ILF3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2D LCE3E LCE4A LINGO1 LNX1 MAPKBP1 MEOX2 MRPL4 NOTCH2NL NPDC1 NUDT18 NUFIP2 OTX1 PCSK5 PDGFRB PFKL PHLDA1 PLSCR1 PLSCR4 PNKP PRKAB2 PRR13 QPRT RERE RPS28 SLC25A10 SLC25A6 SMCP SPATA3 SPG7 SPRY2 TAP1 TBC1D16 TBC1D23 TCEB3B THAP10 THAP7 TOP3B TXNDC5 ZBTB16 ZNF165 ZNF20 ZNF250 ZNF408 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF581 ZNF638 ZNF655 ZNF764 ZSCAN26
Entrez ID		9721	83755
HPRD ID		13804	13941
Ensembl ID			ENSG00000213416
Uniprot IDs		O60269	Q9BQ66
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Signal Transduction Regulation Of Mitochondrion Organization Regulation Of Signal Transduction Apoptotic Process Regulation Of Intracellular Transport Programmed Cell Death Regulation Of Signaling Cell Death Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Catalytic Activity Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Protein Localization Apoptotic Signaling Pathway Intracellular Signal Transduction Regulation Of Endopeptidase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Localization Positive Regulation Of Organelle Organization Synaptic Target Recognition Regulation Of Peptidase Activity Cell Differentiation Regulation Of Protein Metabolic Process Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Heart Rate By Hormone Developmental Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Regulation Of Epidermal Cell Division Negative Regulation Of Protein Serine/threonine Kinase Activity Response To Stimulus Regulation Of Phosphorus Metabolic Process Cellular Response To Stress Regulation Of Proteolysis Positive Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Positive Regulation Of Transport Negative Regulation Of Protein Dephosphorylation	Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Transcription, DNA-templated Biosynthetic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Keratinization Anterior/posterior Pattern Specification Regulation Of Cellular Process Regulation Of Metabolic Process Cellular Process Keratinocyte Differentiation Embryo Development Phospholipid Scrambling Metanephric Glomerulus Vasculature Development Pattern Specification Process Metanephric Glomerulus Development Epidermal Cell Differentiation Epidermis Development Mitochondrion Organization Metabolic Process Forebrain Morphogenesis Transcription From RNA Polymerase II Promoter Glomerulus Vasculature Development Multicellular Organismal Development Organic Anion Transport Inner Ear Development Cell Migration Involved In Coronary Angiogenesis Hepatic Duct Development Abducens Nerve Formation Metanephric Mesenchymal Cell Migration Transepithelial Water Transport Renin Secretion Into Blood Stream Metanephric Descending Thin Limb Development DGDP Catabolic Process Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development
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