DYNLL2 and ZAR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DYNLL2	ZAR1
Description		dynein light chain LC8-type 2	zygote arrest 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Microtubule Associated Complex Plasma Membrane Cilium Postsynaptic Density Microtubule Cytoskeleton Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse	Cytoplasm Cytoplasmic Ribonucleoprotein Granule Intracellular Membraneless Organelle
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Scaffold Protein Binding	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding Metal Ion Binding RNA Sequestering Activity Molecular Condensate Scaffold Activity
	Biological Process	Microtubule-based Process	Oocyte Maturation Translation Negative Regulation Of Translation Cell Differentiation MRNA Stabilization Oogenesis Membraneless Organelle Assembly
Pathways		Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Bipolar disorder ( 31043756) Menopause (age at onset) ( 29773799)
Interacting Genes		30 interacting genes: BMF C14orf119 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HOMER3 IHO1 MEOX2 MORN3 MYO5A OTUD6A PAK1 PKIA PKIG RASGRP3 REDIC1 SKAP1 SMCP SPAG8 THAP10 TPPP XIAP ZAR1	1 interacting genes: DYNLL2
Entrez ID		140735	326340
HPRD ID		06489	09599
Ensembl ID		ENSG00000264364	ENSG00000182223
Uniprot IDs		Q96FJ2	B9EG67 Q86SH2
PDB IDs		2XQQ 3P8M 4D07 7CNU
Enriched GO Terms of Interacting Partners?		Microtubule Binding	Myosin V Complex 9+0 Non-motile Cilium Dynein Intermediate Chain Binding Cytoplasmic Dynein Complex Microtubule Associated Complex Dynein Complex Ciliary Tip Scaffold Protein Binding Postsynaptic Density Microtubule Cytoskeleton Postsynapse Microtubule Protein-containing Complex Binding
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