GPRIN2 and HAPLN2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		GPRIN2	HAPLN2
Name		G protein regulated inducer of neurite outgrowth 2	hyaluronan and proteoglycan link protein 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Extracellular Region Extracellular Space Extracellular Matrix Node Of Ranvier Synapse Perineuronal Net
	Molecular Function	Protein Binding	Protein Binding Hyaluronic Acid Binding
	Biological Process	Neuron Projection Development	Skeletal System Development Cell Adhesion Central Nervous System Development Establishment Of Blood-nerve Barrier Extracellular Matrix Assembly
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		3 novel interactors: ARHGAP22 MAPK8 WDFY4	None recorded
Interacting Genes		27 interacting genes: ANKS1A BCAP31 CYSRT1 DYNLL1 DYNLL2 FRS3 HAPLN2 HTR4 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP4-12 KRTAP4-7 LNP1 MDFI OTX1 PLSCR1 RHOU SFN SPRY2 TRIM55 TRIM63 TRIP13 YWHAE	47 interacting genes: ASB13 BANP CCDC125 CIDEB EXOSC8 FHL3 FHL5 FNDC3B GOLGA6L9 GPRIN2 KRT15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT37 KRT40 KRT85 KRTAP10-8 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP6-2 KRTAP6-3 KRTAP9-2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OIP5 PFDN5 PM20D2 PNMA1 PNMA2 PPP1R16B PSTPIP1 SEC13 SSC4D TFCP2 TRIM23 TRIM27 VWC2 ZMYND12 ZNF438 ZNF655
Entrez ID		9721	60484
HPRD ID		13804	17088
Ensembl ID		ENSG00000204175	ENSG00000132702
Uniprot IDs		O60269	B7Z1R1 Q9GZV7
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Keratin Filament Positive Regulation Of Establishment Of Protein Localization Phosphoserine Residue Binding Protein Sequestering Activity Positive Regulation Of Intracellular Transport Identical Protein Binding Regulation Of Establishment Of Protein Localization Scaffold Protein Binding Microtubule Protein Localization To Endoplasmic Reticulum Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Intracellular Protein Transport	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Identical Protein Binding Cytoskeleton Organization Epidermis Development Keratinization Negative Regulation Of Viral Transcription COPII Vesicle Coat Suppression Of Viral Release By Host Protein Binding COPII-coated Vesicle Cargo Loading Regulation Of Viral Transcription Cytosol Cytoskeleton