DYNLL2 and DPPA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DYNLL2	DPPA3
Description		dynein light chain LC8-type 2	developmental pluripotency associated 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Microtubule Associated Complex Plasma Membrane Cilium Postsynaptic Density Microtubule Cytoskeleton Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse	Female Pronucleus Male Pronucleus Nucleus Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Scaffold Protein Binding	Protein Binding Histone H3K9me2/3 Reader Activity
	Biological Process	Microtubule-based Process	Chromatin Organization Epigenetic Programing Of Female Pronucleus
Pathways		Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation	Chromatin modifications during the maternal to zygotic transition (MZT)
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		30 interacting genes: BMF C14orf119 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HOMER3 IHO1 MEOX2 MORN3 MYO5A OTUD6A PAK1 PKIA PKIG RASGRP3 REDIC1 SKAP1 SMCP SPAG8 THAP10 TPPP XIAP ZAR1	15 interacting genes: CFTR DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618
Entrez ID		140735	359787
HPRD ID		06489	16331
Ensembl ID		ENSG00000264364	ENSG00000187569
Uniprot IDs		Q96FJ2	Q6W0C5
PDB IDs		2XQQ 3P8M 4D07 7CNU	8WMS 8XV7 8XV8
Enriched GO Terms of Interacting Partners?		Microtubule Binding
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