DYNLL2 and DNAL4

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		DYNLL2	DNAL4
Gene Name		dynein, light chain, LC8-type 2	dynein, axonemal, light chain 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Cytosol Microtubule Plasma Membrane Membrane Myosin Complex Dynein Complex Primary Cilium Ciliary Tip	Cytoplasm Microtubule Plasma Membrane Cilium Dynein Complex
	Molecular Function	Motor Activity Protein Binding Cytoskeletal Protein Binding	Motor Activity
	Biological Process	Transport Apoptotic Process Organelle Organization Microtubule-based Process Synaptic Target Recognition Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Microtubule-based Process Metabolic Process Neurotrophin TRK Receptor Signaling Pathway
Pathways		Organelle biogenesis and maintenance MHC class II antigen presentation Programmed Cell Death Activation of BH3-only proteins Assembly of the primary cilium Intraflagellar transport Adaptive Immune System Intrinsic Pathway for Apoptosis Activation of BMF and translocation to mitochondria	Retrograde neurotrophin signalling Signalling by NGF NGF signalling via TRKA from the plasma membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: BCL2L11 BMF C12orf40 CCDC36 DLGAP1 DNAL4 DYNC1I1 EWSR1 GPHN GPRIN2 HMBOX1 HOMER3 MEOX2 MORN3 MYO5A PAK1 RASGRP3 SECISBP2L THAP10 XIAP	9 interactors: CAMK2D DYNLL2 FHL5 GNA14 GPBP1 KRTAP10-3 NOTCH2NL SCTR TRIM54
Entrez ID		140735	10126
HPRD ID		06489	13239
Ensembl ID			ENSG00000100246
Uniprot IDs		Q96FJ2	O96015 Q6FGD0
PDB IDs		2XQQ 3P8M
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Homooligomerization Positive Regulation Of Protein Oligomerization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Release Of Cytochrome C From Mitochondria Synapse Organization Regulation Of Protein Oligomerization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Death Death Regulation Of Intracellular Signal Transduction Receptor Clustering Neuromuscular Junction Development Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Glycine Receptor Clustering Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Developmental Pigmentation Positive Regulation Of Cellular Component Biogenesis Apoptotic Signaling Pathway Protein Localization To Membrane Membrane Organization Positive Regulation Of Protein Linear Polyubiquitination Signaling Regulation Of Mitochondrion Organization Cellular Localization Positive Regulation Of Organelle Organization Cell Communication Vesicle Transport Along Actin Filament Establishment Of Synaptic Specificity At Neuromuscular Junction Endoplasmic Reticulum Localization Apoptotic Process Pigmentation Programmed Cell Death Apoptotic Process Involved In Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process By Virus Odontogenesis Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Intracellular Signal Transduction Regulation Of Signal Transduction Positive Regulation Of Fibroblast Apoptotic Process Somite Specification Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Thymocyte Apoptotic Process Anoikis Locomotion Involved In Locomotory Behavior Histone H3-T11 Phosphorylation	Synaptic Target Recognition Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Rac Protein Signal Transduction Regulation Of Histone Deacetylase Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Signal Transduction Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Relaxation Of Cardiac Muscle Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Organelle Organization Phospholipase C-activating Dopamine Receptor Signaling Pathway Regulation Of Relaxation Of Muscle Cellular Potassium Ion Homeostasis Cell Growth Involved In Cardiac Muscle Cell Development Signaling Cell Communication Regulation Of Cellular Process Negative Regulation Of Sodium Ion Transport Regulation Of Cell Communication By Electrical Coupling
Tagcloud ?		associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynlrb1 dynlt1 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Difference) ?		associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynlrb1 dynlt1 dynlt3 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Intersection) ?