GPRIN2 and SFN

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GPRIN2	SFN
Gene Name		G protein regulated inducer of neurite outgrowth 2	stratifin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Extracellular Space Nucleus Cytoplasm Cytosol Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein Kinase C Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Phosphoprotein Binding
	Biological Process		Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Release Of Cytochrome C From Mitochondria Keratinocyte Development Negative Regulation Of Protein Kinase Activity Apoptotic Process Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Epidermal Cell Division Negative Regulation Of Keratinocyte Proliferation Positive Regulation Of Cell Growth Keratinization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Protein Export From Nucleus Membrane Organization Establishment Of Skin Barrier Negative Regulation Of Protein Serine/threonine Kinase Activity Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Pathways			Activation of BAD and translocation to mitochondria Programmed Cell Death Translocation of GLUT4 to the plasma membrane Activation of BH3-only proteins Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: BCAP31 DYNLL2 KRTAP10-3 KRTAP12-1 KRTAP4-12 KRTAP4-7 MDFI PLSCR1 SFN SPRY2 TRIP13 YWHAE	49 interactors: ABL1 BAD BAX BCR CCAR1 CCDC102B CCNH CDC25B CDK1 CHST1 EEF1A1 EGFR EIF2S1 EIF4B EXO1 FAM189A2 FAM53C FAM9B FOXO4 GPRIN2 HDAC5 HNRNPD ING1 KCNK15 KCNK3 KCNK9 KIAA0408 LONRF1 MAGEA1 MAP3K5 MARK3 MDM4 MKRN3 MST1R NR3C1 PLEKHF2 PLK4 RAB3IP RFFL RFWD2 SAMSN1 TBL3 TP53 TRIM25 TSC2 WDYHV1 YWHAG ZC2HC1C ZFP36
Entrez ID		9721	2810
HPRD ID		13804	03185
Ensembl ID			ENSG00000175793
Uniprot IDs		O60269	P31947
PDB IDs			1YWT 1YZ5 3IQJ 3IQU 3IQV 3LW1 3MHR 3O8I 3P1N 3P1O 3P1P 3P1Q 3P1R 3P1S 3SMK 3SML 3SMM 3SMN 3SMO 3SPR 3T0L 3T0M 3U9X 3UX0 4DAT 4DAU 4DHM 4DHN 4DHO 4DHP 4DHQ 4DHR 4DHS 4DHT 4DHU 4FR3 4HQW 4HRU 4IEA 4JC3 4JDD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Signal Transduction Regulation Of Mitochondrion Organization Regulation Of Signal Transduction Apoptotic Process Regulation Of Intracellular Transport Programmed Cell Death Regulation Of Signaling Cell Death Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Catalytic Activity Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Protein Localization Apoptotic Signaling Pathway Intracellular Signal Transduction Regulation Of Endopeptidase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Localization Positive Regulation Of Organelle Organization Synaptic Target Recognition Regulation Of Peptidase Activity Cell Differentiation Regulation Of Protein Metabolic Process Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Heart Rate By Hormone Developmental Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Regulation Of Epidermal Cell Division Negative Regulation Of Protein Serine/threonine Kinase Activity Response To Stimulus Regulation Of Phosphorus Metabolic Process Cellular Response To Stress Regulation Of Proteolysis Positive Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Positive Regulation Of Transport Negative Regulation Of Protein Dephosphorylation	Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Neuron Death Cell Cycle Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Cellular Response To Organic Substance Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Kinase Activity Cellular Response To Organonitrogen Compound Regulation Of Phosphorus Metabolic Process Cell Cycle Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Mitotic Cell Cycle Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Intracellular Signal Transduction ERBB Signaling Pathway Regulation Of Protein Kinase Activity Response To Stress Mitotic Cell Cycle Positive Regulation Of Cell Cycle Response To Organic Substance Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Cycle Positive Regulation Of Protein Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Catalytic Activity Cellular Response To Insulin Stimulus G2/M Transition Of Mitotic Cell Cycle Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Mitochondrion Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Hormone Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Signal Transduction Cellular Response To Hormone Stimulus Regulation Of Cell Proliferation B Cell Activation Fc Receptor Signaling Pathway
Tagcloud ?			aging alarm amplitude auditory circuits cortico elderly electrophysiologically employed false finding frontal impairments latency limbic memory n4 p3 perform position potentials prefrontal recency serial sternberg subjects task working young
Tagcloud (Difference) ?			aging alarm amplitude auditory circuits cortico elderly electrophysiologically employed false finding frontal impairments latency limbic memory n4 p3 perform position potentials prefrontal recency serial sternberg subjects task working young
Tagcloud (Intersection) ?