EZR and CLIC5

Number of citations of the paper that reports this interaction (PMID 10793131)
29

Data Source:
HPRD (in vitro)

		EZR	CLIC5
Gene Name		ezrin	chloride intracellular channel 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Uropod Extracellular Space Nucleolus Cytosol Actin Filament Plasma Membrane Microvillus Focal Adhesion Actin Cytoskeleton Membrane Basolateral Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Filopodium T-tubule Cortical Cytoskeleton Microvillus Membrane Vesicle Ruffle Membrane Ciliary Basal Body Cell Body Microspike Membrane Raft Apical Part Of Cell Cell Tip Extracellular Vesicular Exosome Cell Periphery Astrocyte Projection Schwann Cell Microvillus	Golgi Apparatus Microtubule Organizing Center Cell Cortex Actin Cytoskeleton Stereocilium Chloride Channel Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Poly(A) RNA Binding Cell Adhesion Molecule Binding Actin Filament Binding	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Cytoskeletal Anchoring At Plasma Membrane Leukocyte Cell-cell Adhesion Axon Guidance Regulation Of Cell Shape Positive Regulation Of Gene Expression Membrane To Membrane Docking Microvillus Assembly Receptor Internalization Establishment Of Epithelial Cell Apical/basal Polarity Filopodium Assembly Actin Filament Bundle Assembly Establishment Of Endothelial Barrier	Diet Induced Thermogenesis Transport Chloride Transport Female Pregnancy Sensory Perception Of Sound Protein Localization Regulation Of Ion Transmembrane Transport Neuromuscular Process Controlling Balance Auditory Receptor Cell Stereocilium Organization Chloride Transmembrane Transport
Pathways		Axon guidance L1CAM interactions Netrin-1 signaling Recycling pathway of L1
Drugs
Diseases
GWAS			Periodontal microbiota ( 22699663)
Protein-Protein Interactions		49 interactors: ACTB ACTC1 ADORA2B ADRA1B ARF6 ARHGDIB CD44 CDH1 CDK5 CFTR CLIC5 CTNNB1 DLG1 EGFR FAS FASLG GZMM ICAM1 ICAM2 ICAM3 IQGAP1 L1CAM LCK MDM2 MPP3 MSN NF2 PALLD PIK3R1 PRKAR2A PRKCA PTK2 PTPRC RDX ROCK1 S100P SCYL3 SDC2 SELL SELP SLC9A3R1 SLC9A3R2 SPN TBC1D10A TMEM8B TSC1 VCAM1 WFDC1 WWOX	6 interactors: ACTA1 ACTN1 EZR GSN IQGAP1 SRPK1
Entrez ID		7430	53405
HPRD ID		00475	06292
Ensembl ID		ENSG00000092820	ENSG00000112782
Uniprot IDs		P15311	Q49AE1 Q53G01 Q9NZA1
PDB IDs		1NI2
Enriched GO Terms of Interacting Partners?		Cell Adhesion Single Organismal Cell-cell Adhesion Movement Of Cell Or Subcellular Component Locomotion Cell Migration Regulation Of Immune System Process Regulation Of Cell Adhesion Cell Motility Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Response To Organic Substance Leukocyte Migration Regulation Of Signaling Leukocyte Cell-cell Adhesion Organ Development Membrane To Membrane Docking Positive Regulation Of Cellular Protein Metabolic Process Response To Organonitrogen Compound Regulation Of Cell-cell Adhesion Cell Differentiation Immune System Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Immune Response Regulation Of Phosphorylation Cell Activation Apoptotic Process Regulation Of Protein Metabolic Process Programmed Cell Death Regulation Of Immune Response System Development Response To Growth Factor Cell Death Anatomical Structure Development Death Response To External Stimulus Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Multicellular Organismal Development Blood Coagulation Developmental Process Hemostasis Defense Response Response To Radiation Positive Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Response To Stimulus Cell Development Regulation Of Body Fluid Levels	Actin Filament Organization Actin Cytoskeleton Organization Actin Filament-based Process Cell Development Response To Metal Ion Cytoskeleton Organization Actin Filament Bundle Assembly Response To Inorganic Substance Growth Organelle Organization Cell Differentiation Tissue Development Cellular Response To Metal Ion Skeletal Muscle Fiber Adaptation Cellular Response To Inorganic Substance Cellular Component Assembly Cell Growth Cell Projection Morphogenesis Cell Part Morphogenesis Protein Localization To Tight Junction Epithelial Cell Development Membrane To Membrane Docking Anatomical Structure Morphogenesis Cell Morphogenesis Skeletal Muscle Thin Filament Assembly Response To Stimulus Anatomical Structure Development Developmental Growth Cell Projection Organization Protein Localization To Cell Junction Skeletal Myofibril Assembly Sperm Chromatin Condensation Skeletal Muscle Adaptation Glomerular Visceral Epithelial Cell Development Cytoskeletal Anchoring At Plasma Membrane Developmental Process Response To Folic Acid Actin Filament Severing Microvillus Assembly Vesicle-mediated Transport Microvillus Organization Glomerular Visceral Epithelial Cell Differentiation Cellular Response To Cadmium Ion Actin Crosslink Formation Filopodium Assembly Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Response To Extracellular Stimulus Positive Regulation Of Viral Genome Replication Barbed-end Actin Filament Capping
Tagcloud ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf	assayed buck chose conditional cxcl13 dichotomization dichotomous dr ffpe hrneg hrpos ics incorporating microarray multigene multiplexed nodal optimized platforms prognostically proved reaffirmed rtpcr signatures subtyping tneg tnfrsf17 today xcl2
Tagcloud (Difference) ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp slc9a2 vwf	assayed buck chose conditional cxcl13 dichotomization dichotomous dr ffpe hrneg hrpos ics incorporating microarray multigene multiplexed nodal optimized platforms prognostically proved reaffirmed rtpcr subtyping tneg tnfrsf17 today xcl2
Tagcloud (Intersection) ?		signatures