EZR and S100P

Number of citations of the paper that reports this interaction (PMID 12808036)
16

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vitro)

		EZR	S100P
Gene Name		ezrin	S100 calcium binding protein P
Image
Gene Ontology Annotations	Cellular Component	Ruffle Uropod Extracellular Space Nucleolus Cytosol Actin Filament Plasma Membrane Microvillus Focal Adhesion Actin Cytoskeleton Membrane Basolateral Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Filopodium T-tubule Cortical Cytoskeleton Microvillus Membrane Vesicle Ruffle Membrane Ciliary Basal Body Cell Body Microspike Membrane Raft Apical Part Of Cell Cell Tip Extracellular Vesicular Exosome Cell Periphery Astrocyte Projection Schwann Cell Microvillus	Nucleus Cytoplasm Microvillus Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding Poly(A) RNA Binding Cell Adhesion Molecule Binding Actin Filament Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Cytoskeletal Anchoring At Plasma Membrane Leukocyte Cell-cell Adhesion Axon Guidance Regulation Of Cell Shape Positive Regulation Of Gene Expression Membrane To Membrane Docking Microvillus Assembly Receptor Internalization Establishment Of Epithelial Cell Apical/basal Polarity Filopodium Assembly Actin Filament Bundle Assembly Establishment Of Endothelial Barrier	Response To Organic Substance Endothelial Cell Migration
Pathways		Axon guidance L1CAM interactions Netrin-1 signaling Recycling pathway of L1
Drugs			Cromoglicic acid
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		49 interactors: ACTB ACTC1 ADORA2B ADRA1B ARF6 ARHGDIB CD44 CDH1 CDK5 CFTR CLIC5 CTNNB1 DLG1 EGFR FAS FASLG GZMM ICAM1 ICAM2 ICAM3 IQGAP1 L1CAM LCK MDM2 MPP3 MSN NF2 PALLD PIK3R1 PRKAR2A PRKCA PTK2 PTPRC RDX ROCK1 S100P SCYL3 SDC2 SELL SELP SLC9A3R1 SLC9A3R2 SPN TBC1D10A TMEM8B TSC1 VCAM1 WFDC1 WWOX	12 interactors: AGER CACYBP EZR S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11
Entrez ID		7430	6286
HPRD ID		00475	02792
Ensembl ID		ENSG00000092820
Uniprot IDs		P15311	P25815
PDB IDs		1NI2	1J55 1OZO
Enriched GO Terms of Interacting Partners?		Cell Adhesion Single Organismal Cell-cell Adhesion Movement Of Cell Or Subcellular Component Locomotion Cell Migration Regulation Of Immune System Process Regulation Of Cell Adhesion Cell Motility Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Response To Organic Substance Leukocyte Migration Regulation Of Signaling Leukocyte Cell-cell Adhesion Organ Development Membrane To Membrane Docking Positive Regulation Of Cellular Protein Metabolic Process Response To Organonitrogen Compound Regulation Of Cell-cell Adhesion Cell Differentiation Immune System Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Immune Response Regulation Of Phosphorylation Cell Activation Apoptotic Process Regulation Of Protein Metabolic Process Programmed Cell Death Regulation Of Immune Response System Development Response To Growth Factor Cell Death Anatomical Structure Development Death Response To External Stimulus Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Multicellular Organismal Development Blood Coagulation Developmental Process Hemostasis Defense Response Response To Radiation Positive Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Response To Stimulus Cell Development Regulation Of Body Fluid Levels	Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Spliceosomal Complex Disassembly Negative Regulation Of DNA Recombination At Telomere System Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Chaperone-mediated Protein Complex Assembly Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Skeletal Muscle Cell Differentiation Multicellular Organismal Development Membrane To Membrane Docking Protection From Non-homologous End Joining At Telomere Anatomical Structure Development Regulation Of Cell Shape Telomere Capping Protein Localization To Chromosome, Telomeric Region Ubiquitin-dependent SMAD Protein Catabolic Process Cell Morphogenesis Involved In Differentiation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Developmental Process Response To Methylmercury Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance
Tagcloud ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf	adenoma bda bdas bile columnar cuboidal duct ductular ema glut imp indexes interlobular lumen meyenburg morphologic muc1 muc6 narrow ncam nodular peribiliary resembling sclerotic sized stroma uniform vmc von
Tagcloud (Difference) ?		actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf	adenoma bda bdas bile columnar cuboidal duct ductular ema glut imp indexes interlobular lumen meyenburg morphologic muc1 muc6 narrow ncam nodular peribiliary resembling sclerotic sized stroma uniform vmc von
Tagcloud (Intersection) ?