EIF4E2 and NECAB2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EIF4E2	NECAB2
Gene Name		eukaryotic translation initiation factor 4E family member 2	N-terminal EF-hand calcium binding protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol MRNA Cap Binding Complex	Cytoplasm
	Molecular Function	RNA Cap Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, Nucleic Acid Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding	Calcium Ion Binding Protein Binding
	Biological Process	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation Cytokine-mediated Signaling Pathway
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS		Non-small cell lung cancer ( 21079520)
Protein-Protein Interactions		44 interactors: ADAMTSL4 AES AMOTL2 APP ARIH1 CARD9 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MYOG NECAB2 NOTCH2NL PRDM14 REL SPAG5 SPERT SPRY2 TADA2A TCF4 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9	53 interactors: AIMP2 BEX2 BYSL C1orf109 CAPN3 CARD9 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO DAXX DFFA DGCR6 DGCR6L EHHADH EIF4E2 FAM161A FXR2 GCC1 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NGFRAP1 NIP7 NOC4L PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USP7 VTA1 WDYHV1
Entrez ID		9470	54550
HPRD ID		05798	13263
Ensembl ID		ENSG00000135930	ENSG00000103154
Uniprot IDs		B4E1E4 B8ZZL3 O60573 Q53RG0	Q7Z6G3
PDB IDs		2JGB 2JGC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Binding Negative Regulation Of Gene Expression Regulation Of Protein Binding Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Wnt Signaling Pathway Cellular Response To Stimulus Regulation Of Gene Expression Mitotic Cell Cycle Process Regulation Of Phosphorylation Negative Regulation Of Translational Initiation Response To Organic Substance Cell Cycle Regulation Of Protein Kinase Activity Cell Cycle Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Mitotic Cell Cycle Regulation Of Protein Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Positive Regulation Of Cell Cycle Regulation Of Protein Localization Signal Transduction Regulation Of Kinase Activity Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Phosphorus Metabolic Process Negative Regulation Of RNA Biosynthetic Process Cell Fate Commitment Positive Regulation Of Intracellular Signal Transduction Cytoskeleton Organization Regulation Of Wnt Signaling Pathway Cell Differentiation Involved In Embryonic Placenta Development Mitotic Nuclear Division Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Metabolic Process Signaling Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stimulus Histone H3-R26 Methylation Positive Regulation Of Muscle Atrophy Inner Cell Mass Cell Fate Commitment Cell Communication	Organelle Organization Cell Cycle Regulation Of Apoptotic Process Apoptotic Process Ribosome Biogenesis Regulation Of Cell Death Programmed Cell Death Regulation Of Protein Metabolic Process Cell Cycle Process Cellular Component Assembly Cell Death Death Chromatin Modification Regulation Of Cellular Protein Metabolic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA Positive Regulation Of JNK Cascade Organelle Assembly Cell-cell Adhesion Involved In Gastrulation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Apoptotic DNA Fragmentation Nitrogen Fixation Autolysis Chromatin Organization Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Tagcloud ?		abundant accumulated arabidopsis cdnas cerevisiae complementation complemented conditional deduced floral grew homologous iso isogenic mammals mapping monocotyledonous mrnas northern organs roots saccharomyces specialization thaliana yac yeast zone
Tagcloud (Difference) ?		abundant accumulated arabidopsis cdnas cerevisiae complementation complemented conditional deduced floral grew homologous iso isogenic mammals mapping monocotyledonous mrnas northern organs roots saccharomyces specialization thaliana yac yeast zone
Tagcloud (Intersection) ?