EIF4E2 and USP54

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EIF4E2	USP54
Gene Name		eukaryotic translation initiation factor 4E family member 2	ubiquitin specific peptidase 54
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol MRNA Cap Binding Complex
	Molecular Function	RNA Cap Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, Nucleic Acid Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding	Protein Binding Ubiquitinyl Hydrolase Activity
	Biological Process	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation Cytokine-mediated Signaling Pathway	Ubiquitin-dependent Protein Catabolic Process
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS		Non-small cell lung cancer ( 21079520)
Protein-Protein Interactions		44 interactors: ADAMTSL4 AES AMOTL2 APP ARIH1 CARD9 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MYOG NECAB2 NOTCH2NL PRDM14 REL SPAG5 SPERT SPRY2 TADA2A TCF4 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9	8 interactors: ATN1 ATXN1 CHMP1B CHMP2A CHMP2B CHMP4C EIF4E2 NXT2
Entrez ID		9470	159195
HPRD ID		05798	15641
Ensembl ID		ENSG00000135930	ENSG00000166348
Uniprot IDs		B4E1E4 B8ZZL3 O60573 Q53RG0	Q70EL1
PDB IDs		2JGB 2JGC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Binding Negative Regulation Of Gene Expression Regulation Of Protein Binding Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Wnt Signaling Pathway Cellular Response To Stimulus Regulation Of Gene Expression Mitotic Cell Cycle Process Regulation Of Phosphorylation Negative Regulation Of Translational Initiation Response To Organic Substance Cell Cycle Regulation Of Protein Kinase Activity Cell Cycle Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Mitotic Cell Cycle Regulation Of Protein Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Positive Regulation Of Cell Cycle Regulation Of Protein Localization Signal Transduction Regulation Of Kinase Activity Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Phosphorus Metabolic Process Negative Regulation Of RNA Biosynthetic Process Cell Fate Commitment Positive Regulation Of Intracellular Signal Transduction Cytoskeleton Organization Regulation Of Wnt Signaling Pathway Cell Differentiation Involved In Embryonic Placenta Development Mitotic Nuclear Division Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Metabolic Process Signaling Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stimulus Histone H3-R26 Methylation Positive Regulation Of Muscle Atrophy Inner Cell Mass Cell Fate Commitment Cell Communication	Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Centrosome Cycle Vacuolar Transport Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Nucleus Organization Regulation Of Mitotic Nuclear Division Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Chromosome Segregation Regulation Of Cell Division Viral Budding Via Host ESCRT Complex Mitotic Nuclear Division Positive Regulation Of Viral Release From Host Cell Establishment Of Organelle Localization Regulation Of Protein Complex Assembly Viral Budding Regulation Of Mitotic Cell Cycle Organelle Localization Cell Division Regulation Of Cell Cycle Process Regulation Of Cytoskeleton Organization Regulation Of Viral Release From Host Cell Virion Assembly Viral Life Cycle Protein Transport Endosomal Transport Mitotic Cell Cycle Process Establishment Of Protein Localization Intracellular Transport Mitotic Cell Cycle Regulation Of Organelle Organization Regulation Of Cell Cycle Protein Localization Establishment Of Localization In Cell Chromosome Organization Cell Cycle Process Positive Regulation Of Viral Process Membrane Budding Negative Regulation Of Centriole Elongation Cellular Localization Cell Cycle Viral Process
Tagcloud ?		abundant accumulated arabidopsis cdnas cerevisiae complementation complemented conditional deduced floral grew homologous iso isogenic mammals mapping monocotyledonous mrnas northern organs roots saccharomyces specialization thaliana yac yeast zone
Tagcloud (Difference) ?		abundant accumulated arabidopsis cdnas cerevisiae complementation complemented conditional deduced floral grew homologous iso isogenic mammals mapping monocotyledonous mrnas northern organs roots saccharomyces specialization thaliana yac yeast zone
Tagcloud (Intersection) ?