NECAB2 and SSC5D

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		NECAB2	SSC5D
Description		N-terminal EF-hand calcium binding protein 2	scavenger receptor cysteine rich family member with 5 domains
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Axon Dendrite Cell Projection Presynapse Postsynapse	Extracellular Region Extracellular Space Cytoplasm Membrane Extracellular Matrix
	Molecular Function	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding Identical Protein Binding Metal Ion Binding	Fibronectin Binding Scavenger Receptor Activity Protein Binding Laminin Binding Extracellular Matrix Binding
	Biological Process	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane	Immune System Process Defense Response Vesicle-mediated Transport Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-8 Production Detection Of Bacterial Lipoprotein Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways			Scavenging by Class B Receptors
Drugs
Diseases
GWAS		Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)	Height ( 28552196) Lung adenocarcinoma ( 28604730)
Interacting Genes		91 interacting genes: ADORA2A AIMP2 AIRIM BEX2 BEX3 BYSL C19orf25 C1orf216 CAGE1 CAPN3 CARD9 CCDC121 CCDC146 CCDC33 CCNK CDC37 CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L DRC12 DTNBP1 DYNC1I2 EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FAM161B FANCG FMR1 FXR1 FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 INTS10 ISCU KANK2 KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 MSGN1 MTCL2 MTMR9 MYO15B MYPOP NEK6 NIP7 NOC4L NTAQ1 ODAD3 ODAD4 OIP5 PATJ PICK1 POLR2C PRKAA2 PRPF18 PSMA1 PUS10 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SMARCA2 SMARCD1 SNAPIN SSC5D TCEA2 TEX11 TRIM59 TRIML2 TSC1 TTR USHBP1 USP7 VTA1 ZNF655	17 interacting genes: BLOC1S2 CEP170P1 DTNBP1 EXOC7 HAUS1 KRT27 MED11 MED21 MED29 NECAB2 NUP62 PIN1 SDCBP SEC23IP SKA1 TCEA2 TRAF1
Entrez ID		54550	284297
HPRD ID		13263	11444
Ensembl ID		ENSG00000103154	ENSG00000179954
Uniprot IDs		Q7Z6G3	A1L4H1
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Translation Regulator Activity Positive Regulation Of Long-term Neuronal Synaptic Plasticity Presynaptic Modulation Of Chemical Synaptic Transmission Cytoplasm Microtubule Outer Dynein Arm Docking Complex Cellular Component Assembly Microtubule-based Movement Spermatid Development Regulation Of DNA-templated Transcription Elongation RNA Strand Annealing Activity Regulation Of Long-term Neuronal Synaptic Plasticity Organelle Assembly Ribosome Biogenesis Positive Regulation Of Receptor Internalization	Regulation Of DNA-templated Transcription Elongation Core Mediator Complex Cytoskeleton Organization Cellular Component Assembly RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Mediator Complex Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Receptor Internalization Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Mitotic Cytokinesis Organelle Localization Regulation Of Cytokinesis Microtubule-based Process Regulation Of Mitotic Cytokinesis BLOC-1 Complex Negative Regulation Of Receptor Internalization Regulation Of Transcription Elongation By RNA Polymerase II Mitotic Spindle Microtubule Anterograde Synaptic Vesicle Transport Regulation Of Mitotic Nuclear Division Regulation Of Receptor-mediated Endocytosis Organelle Organization Transcription Coregulator Activity Platelet Dense Granule Organization Centrosome Regulation Of Nuclear Division Negative Regulation Of Receptor-mediated Endocytosis Flemming Body Regulation Of Microtubule Cytoskeleton Organization Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Regulation Of Cell Division Midbody Protein-DNA Complex Assembly Positive Regulation Of Cytokinesis Microtubule Cytoskeleton Organization Anterograde Axonal Transport Cis-trans Isomerase Activity Interleukin-5 Receptor Complex Positive Regulation Of Mitotic Nuclear Division Mitotic Metaphase Chromosome Alignment Vesicle Transport Along Microtubule Establishment Of Protein Localization
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