NECAB2 and CENPO

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		NECAB2	CENPO
Gene Name		N-terminal EF-hand calcium binding protein 2	centromere protein O
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Condensed Chromosome Kinetochore Nucleoplasm Cytosol
	Molecular Function	Calcium Ion Binding Protein Binding
	Biological Process		Mitotic Cell Cycle Nucleosome Assembly CENP-A Containing Nucleosome Assembly
Pathways			Mitotic Prometaphase Chromosome Maintenance Nucleosome assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Height ( 23563607) Type 1 diabetes ( 21980299)
Protein-Protein Interactions		53 interactors: AIMP2 BEX2 BYSL C1orf109 CAPN3 CARD9 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO DAXX DFFA DGCR6 DGCR6L EHHADH EIF4E2 FAM161A FXR2 GCC1 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NGFRAP1 NIP7 NOC4L PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USP7 VTA1 WDYHV1	5 interactors: CENPP CEP170P1 ERI3 FOS NECAB2
Entrez ID		54550	79172
HPRD ID		13263	14414
Ensembl ID		ENSG00000103154	ENSG00000138092
Uniprot IDs		Q7Z6G3	Q9BU64
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Regulation Of Apoptotic Process Apoptotic Process Ribosome Biogenesis Regulation Of Cell Death Programmed Cell Death Regulation Of Protein Metabolic Process Cell Cycle Process Cellular Component Assembly Cell Death Death Chromatin Modification Regulation Of Cellular Protein Metabolic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA Positive Regulation Of JNK Cascade Organelle Assembly Cell-cell Adhesion Involved In Gastrulation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Apoptotic DNA Fragmentation Nitrogen Fixation Autolysis Chromatin Organization Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade	Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Conditioned Taste Aversion RRNA 3'-end Processing Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Sleep Response To Gravity Maturation Of 5.8S RRNA Response To Immobilization Stress CENP-A Containing Nucleosome Assembly Positive Regulation Of Osteoclast Differentiation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Histone Exchange Response To Corticosterone DNA Replication-independent Nucleosome Assembly Response To Mineralocorticoid Centromere Complex Assembly Cellular Response To Calcium Ion Response To Progesterone Positive Regulation Of Myeloid Leukocyte Differentiation Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway SMAD Protein Signal Transduction Response To Cold Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Skeletal Muscle Cell Differentiation Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway DNA Methylation TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway ATP-dependent Chromatin Remodeling Toll-like Receptor 3 Signaling Pathway Regulation Of Osteoclast Differentiation
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