Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
NECAB2 and NGFRAP1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
NECAB2
NGFRAP1
Gene Name
N-terminal EF-hand calcium binding protein 2
nerve growth factor receptor (TNFRSF16) associated protein 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Nucleus
Cytoplasm
Cytosol
Molecular Function
Calcium Ion Binding
Protein Binding
Death Receptor Binding
Protein Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Metal Ion Binding
Biological Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Multicellular Organismal Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Neurotrophin TRK Receptor Signaling Pathway
Apoptotic Signaling Pathway
Pathways
Signalling by NGF
Cell death signalling via NRAGE, NRIF and NADE
p75 NTR receptor-mediated signalling
NADE modulates death signalling
Drugs
Diseases
GWAS
Protein-Protein Interactions
53 interactors:
AIMP2
BEX2
BYSL
C1orf109
CAPN3
CARD9
CCDC146
CCDC151
CCDC153
CCDC33
CCNK
CENPO
DAXX
DFFA
DGCR6
DGCR6L
EHHADH
EIF4E2
FAM161A
FXR2
GCC1
GTPBP10
HAUS1
INPP1
ISCU
KANSL1
KDM1A
KIFC3
KLC3
KLC4
KPNA2
LENG1
LNX1
MED14
MRPS27
NEK6
NGFRAP1
NIP7
NOC4L
PRKAA2
PSMA1
RCOR3
RIC8A
RUNX1T1
SDCBP
SH2D4A
SSC5D
TEX11
TTC25
TTR
USP7
VTA1
WDYHV1
28 interactors:
AIMP2
CACYBP
CCDC116
CCDC85B
CTNNBL1
DIABLO
EMILIN1
FSD2
GOLGA8EP
GOLGA8F
MIF
MNAT1
NECAB2
NGFR
NTRK3
PTPN13
SIVA1
SMPD1
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
TSC1
USHBP1
VTA1
YWHAE
Entrez ID
54550
27018
HPRD ID
13263
02291
Ensembl ID
ENSG00000103154
ENSG00000166681
Uniprot IDs
Q7Z6G3
Q00994
PDB IDs
1SA6
Enriched GO Terms of Interacting Partners
?
Organelle Organization
Cell Cycle
Regulation Of Apoptotic Process
Apoptotic Process
Ribosome Biogenesis
Regulation Of Cell Death
Programmed Cell Death
Regulation Of Protein Metabolic Process
Cell Cycle Process
Cellular Component Assembly
Cell Death
Death
Chromatin Modification
Regulation Of Cellular Protein Metabolic Process
Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Maturation Of SSU-rRNA
Positive Regulation Of JNK Cascade
Organelle Assembly
Cell-cell Adhesion Involved In Gastrulation
Regulation Of Primitive Erythrocyte Differentiation
Negative Regulation Of Apoptotic DNA Fragmentation
Nitrogen Fixation
Autolysis
Chromatin Organization
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Cell Death
Regulation Of Apoptotic Process
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Regulation Of Protein Metabolic Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Signal Transduction
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of Signaling
Positive Regulation Of Signal Transduction
Activation Of NF-kappaB-inducing Kinase Activity
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Metabolic Process
Positive Regulation Of NIK/NF-kappaB Signaling
Regulation Of Catalytic Activity
Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
NIK/NF-kappaB Signaling
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of MAP Kinase Activity
Regulation Of Cellular Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Intracellular Signal Transduction
Regulation Of Phosphorylation
Apoptotic Signaling Pathway
Positive Regulation Of Cytokine Production Involved In Immune Response
Cellular Response To Stimulus
Regulation Of MAPK Cascade
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Negative Regulation Of Cell Death
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Signal Transduction
Regulation Of Cell Proliferation
Positive Regulation Of Apoptotic Signaling Pathway
Response To Organic Substance
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity
Tagcloud
?
abcf2
adprtl1
amy2b
arhgap4
atp6ap1
axin1
casp4
cox1
cox7b
ctsl
etv4
lgals3bp
mgc35136
mgc5528
mt2a
mt3
p53scv
ppia
prdx2
psap
scgb2a2
smoc2
sptan1
sra1
tax1bp1
tpd52l1
tra1
trf4
tuba4
Tagcloud (Difference)
?
abcf2
adprtl1
amy2b
arhgap4
atp6ap1
axin1
casp4
cox1
cox7b
ctsl
etv4
lgals3bp
mgc35136
mgc5528
mt2a
mt3
p53scv
ppia
prdx2
psap
scgb2a2
smoc2
sptan1
sra1
tax1bp1
tpd52l1
tra1
trf4
tuba4
Tagcloud (Intersection)
?