NECAB2 and VTA1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NECAB2	VTA1
Gene Name		N-terminal EF-hand calcium binding protein 2	vesicle (multivesicular body) trafficking 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytosol Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process		Protein Transport Viral Process Endosomal Transport Viral Life Cycle Membrane Organization
Pathways			HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Retinal vascular caliber ( 21060863)
Protein-Protein Interactions		53 interactors: AIMP2 BEX2 BYSL C1orf109 CAPN3 CARD9 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO DAXX DFFA DGCR6 DGCR6L EHHADH EIF4E2 FAM161A FXR2 GCC1 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NGFRAP1 NIP7 NOC4L PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USP7 VTA1 WDYHV1	17 interactors: APP CBS CDK4 CHMP5 DPPA2 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 NGFRAP1 RABAC1 RPIA SSSCA1 ZBTB16
Entrez ID		54550	51534
HPRD ID		13263	09855
Ensembl ID		ENSG00000103154
Uniprot IDs		Q7Z6G3	E7ETQ7 Q9NP79
PDB IDs			2LXL 2LXM
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Regulation Of Apoptotic Process Apoptotic Process Ribosome Biogenesis Regulation Of Cell Death Programmed Cell Death Regulation Of Protein Metabolic Process Cell Cycle Process Cellular Component Assembly Cell Death Death Chromatin Modification Regulation Of Cellular Protein Metabolic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA Positive Regulation Of JNK Cascade Organelle Assembly Cell-cell Adhesion Involved In Gastrulation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Apoptotic DNA Fragmentation Nitrogen Fixation Autolysis Chromatin Organization Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade	Cell Division Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition Lysosome Organization Positive Regulation Of Cell Cycle Phase Transition Cysteine Biosynthetic Process From Serine Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Negative Regulation Of Cell Differentiation Organelle Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Synaptic Growth At Neuromuscular Junction Mast Cell Secretory Granule Organization Transsulfuration Regulation Of Mitotic Cell Cycle Vacuole Organization Collateral Sprouting In Absence Of Injury Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle L-serine Catabolic Process Pentose-phosphate Shunt, Non-oxidative Branch Regulation Of Cell Cycle Process Positive Regulation Of NK T Cell Differentiation Collateral Sprouting Axon Midline Choice Point Recognition Hydrogen Sulfide Metabolic Process Positive Regulation Of Peptidase Activity Endosome Transport Via Multivesicular Body Sorting Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Germ-line Stem Cell Asymmetric Division Regulation Of Cellular Protein Metabolic Process Axon Choice Point Recognition Protein Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cysteine Metabolic Process Secretion Of Lysosomal Enzymes Positive Regulation Of Cell Death Protein Modification By Small Protein Conjugation Regulation Of Response To Osmotic Stress Regulation Of Mitotic Spindle Assembly Regulation Of Signaling Homocysteine Metabolic Process Phospholipid Homeostasis Neuron Remodeling
Tagcloud ?			abscission atpase budding carboxyl cofactor compensatory coordinating cytokinesis endosomal enveloped escrt escrts helices hydrolysis input intergenic lip5 modulates multivesicular oligomer oligomerization rational sbp sorting stimulatory uncovered vps4 vse vsl
Tagcloud (Difference) ?			abscission atpase budding carboxyl cofactor compensatory coordinating cytokinesis endosomal enveloped escrt escrts helices hydrolysis input intergenic lip5 modulates multivesicular oligomer oligomerization rational sbp sorting stimulatory uncovered vps4 vse vsl
Tagcloud (Intersection) ?