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ZFYVE9 and BAG6
Number of citations of the paper that reports this interaction (PubMedID
15231748
)
54
Data Source:
HPRD
(two hybrid)
ZFYVE9
BAG6
Description
zinc finger FYVE-type containing 9
BAG cochaperone 6
Image
GO Annotations
Cellular Component
Cytoplasm
Endosome
Early Endosome
Cytosol
Membrane
Early Endosome Membrane
Protein-containing Complex
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Extracellular Exosome
BAT3 Complex
Molecular Function
Protein Binding
1-phosphatidylinositol Binding
Zinc Ion Binding
Protein Domain Specific Binding
Metal Ion Binding
Signaling Receptor Binding
Protein Binding
Hsp70 Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Ribosome Binding
Receptor Ligand Activity
Misfolded Protein Binding
Molecular Adaptor Activity
Proteasome Binding
Protein Carrier Chaperone
Ubiquitin-specific Protease Binding
Biological Process
Endocytosis
Transforming Growth Factor Beta Receptor Signaling Pathway
Endosomal Transport
Kidney Development
Immune System Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Chromatin Organization
Ubiquitin-dependent Protein Catabolic Process
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Apoptotic Process
Synaptonemal Complex Assembly
Spermatogenesis
Brain Development
Proteasomal Protein Catabolic Process
Internal Peptidyl-lysine Acetylation
Natural Killer Cell Activation
Cell Differentiation
Lung Development
Regulation Of Protein Stability
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
ERAD Pathway
Maintenance Of Unfolded Protein
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteolysis
Regulation Of Embryonic Development
Protein Stabilization
NK T Cell Activation
Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Tail-anchored Membrane Protein Insertion Into ER Membrane
Positive Regulation Of ERAD Pathway
Pathways
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS
Hip circumference adjusted for BMI (
34021172
)
A body shape index (
34021172
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Height (
28552196
)
Hip circumference adjusted for BMI (
34021172
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Schizophrenia (
23894747
)
Small cell lung carcinoma (
28604730
)
Smoking status (ever vs never smokers) (
30643258
)
Ulcerative colitis (
28067908
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
38 interacting genes:
ANKLE2
BAG6
BMP4
CHD6
CLTC
CTNNB1
DAZAP2
EIF4G1
ERBIN
ETS2
FHL2
JUP
LRP12
NIT1
NUP155
PML
PPP1CA
PPP1CB
PPP1CC
PPP2R1A
RBBP6
RHOT2
RNF11
RNPEP
SCYL2
SMAD2
SMAD3
SPART
ST7
SUMF2
SUPT5H
SVEP1
TENT5A
TGFBR1
TGFBR2
UBC
UBXN11
ZMYND8
120 interacting genes:
ACVR1B
AKT1
AMFR
AMTN
ANTKMT
ANXA7
APBB1IP
ARPC3
ATN1
ATXN2
B2M
BCL2
C1QA
CD93
CDK16
CDK4
CDK5
CDKN1A
CDSN
CEBPA
CHN2
CILK1
CLU
CRIPTO
CSNK2B
CSTF2
CTAG1A
CTAG1B
CTCFL
CTSB
CTSE
CTSL
CXCL8
CYSRT1
DMKN
DNAJB11
DPT
DRC9
EDN1
EFEMP1
EFEMP2
ELP1
EP300
FAM9B
FAS
FKBP2
FZD4
GADD45A
GLRA2
GOLGA6L9
GSK3B
HSPA13
HSPA8
IGF2
IGFBP5
IMMT
KLHL12
KPNA2
LBP
MAP1LC3B
MAPK6
MECOM
MEST
MTNR1A
MYDGF
NBL1
NCR3
NDUFA6
NDUFB11
NOMO1
NPY
NR1H2
PELP1
PIN1
PLA2G2A
PLK1
PLPP2
PLPPR3
POLR2J
PRKAR1B
PRMT2
PRNP
PRPF40A
PTH
PTN
PTPN12
RAB8A
RAC1
RCC1
RCN2
REG1B
RNF126
S100A4
SDC2
SEC61A1
SEC61B
SERPING1
SERPINH1
SERPINI2
SETDB1
SGTA
SMN1
SPP1
SRGN
STX5
TAC1
TENT5A
TFCP2
TK1
TOMM20
TP53
TP63
TTR
UBL7
UBQLN1
UBQLN2
UBQLN4
VAMP2
XRN1
ZFYVE9
Entrez ID
9372
7917
HPRD ID
04782
00808
Ensembl ID
ENSG00000157077
ENSG00000204463
Uniprot IDs
O95405
A0A1U9X7A6
A0A7P0MQS5
P46379
PDB IDs
1DEV
1MK2
4BKW
5MJY
1WX9
2N9P
4DWF
4EEW
4WWR
4X86
6AU8
7RU9
7RUA
7RUC
Enriched GO Terms of Interacting Partners
?
Embryonic Cranial Skeleton Morphogenesis
Positive Regulation Of Epithelial To Mesenchymal Transition
Ubiquitin Protein Ligase Binding
Embryonic Skeletal System Morphogenesis
I-SMAD Binding
SMAD Binding
Lung Development
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Regulation Of Epithelial To Mesenchymal Transition
Skeletal System Morphogenesis
Entrainment Of Circadian Clock By Photoperiod
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
SMAD Protein Signal Transduction
Trachea Formation
Trophoblast Cell Migration
PTW/PP1 Phosphatase Complex
Embryonic Organ Morphogenesis
Photoperiodism
Entrainment Of Circadian Clock
Activin Receptor Signaling Pathway
Embryonic Foregut Morphogenesis
Enzyme-linked Receptor Protein Signaling Pathway
Positive Regulation Of SMAD Protein Signal Transduction
Cell Fate Commitment
Tissue Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Tissue Development
Gastrulation
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Branching Involved In Lung Morphogenesis
Tube Morphogenesis
Positive Regulation Of Developmental Process
Regulation Of Chondrocyte Differentiation
Positive Regulation Of Transcription Elongation By RNA Polymerase II
Mesenchyme Development
Regulation Of Developmental Process
Formation Of Primary Germ Layer
Branching Morphogenesis Of An Epithelial Tube
Osteoblast Differentiation
Bronchus Development
Animal Organ Formation
Positive Regulation Of DNA-templated Transcription, Elongation
Catenin-TCF7L2 Complex
Paraxial Mesoderm Morphogenesis
Transforming Growth Factor Beta Ligand-receptor Complex
Regulation Of Translation In Response To Stress
Circadian Regulation Of Gene Expression
In Utero Embryonic Development
Regulation Of SMAD Protein Signal Transduction
Developmental Growth
Regulation Of Cellular Response To Stress
Extracellular Space
Negative Regulation Of Multicellular Organismal Process
Regulation Of Proteolysis
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Extracellular Region
Protein Binding
Membrane Organization
Receptor Ligand Activity
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Response To Endoplasmic Reticulum Stress
Signal Transduction
Response To Hormone
Negative Regulation Of Proteolysis
Extracellular Matrix
Negative Regulation Of Cellular Component Organization
Response To Lipid
Tissue Development
Regulation Of Protein Catabolic Process
Tau Protein Binding
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Leukocyte Apoptotic Process
Positive Regulation Of Neutrophil Chemotaxis
Regulation Of Ossification
G1/S Transition Of Mitotic Cell Cycle
Protein-containing Complex
Establishment Of Protein Localization To Organelle
Molecular Function Activator Activity
Cell Cycle G1/S Phase Transition
Negative Regulation Of Developmental Process
Positive Regulation Of Granulocyte Chemotaxis
Regulation Of Multicellular Organismal Process
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cell Migration
Regulation Of Developmental Process
Response To Nutrient Levels
Cellular Response To Oxygen-containing Compound
Endoplasmic Reticulum Lumen
T Cell Apoptotic Process
Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Cell Cycle
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Cell Motility
Regulation Of Signal Transduction
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Tagcloud (Difference)
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Tagcloud (Intersection)
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