ZFYVE9 and UBXN11

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		ZFYVE9	UBXN11
Gene Name		zinc finger, FYVE domain containing 9	UBX domain protein 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Early Endosome Membrane	Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Serine-type Peptidase Activity Metal Ion Binding	Ubiquitin Binding
	Biological Process	Proteolysis Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway SMAD Protein Complex Assembly SMAD Protein Import Into Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		38 interactors: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBB2IP ETS2 FAM46A FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPG20 ST7 SUMF2 SUPT5H SVEP1 TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	18 interactors: AES C6orf165 EIF4E EIF4E2 ENKD1 PRKAA1 PRKAB2 PSMA1 RHOBTB3 RND1 RND2 RND3 RNF213 SCNM1 SH2D4A TRAF2 USHBP1 ZFYVE9
Entrez ID		9372	91544
HPRD ID		04782	10245
Ensembl ID		ENSG00000157077	ENSG00000158062
Uniprot IDs		O95405	Q5T124
PDB IDs		1DEV 1MK2 4BKW
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Common-partner SMAD Protein Phosphorylation Cell Cycle Trachea Formation Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Embryonic Skeletal System Morphogenesis Entrainment Of Circadian Clock By Photoperiod Embryonic Cranial Skeleton Morphogenesis Cellular Response To Organic Substance Response To Organic Substance Photoperiodism Entrainment Of Circadian Clock Embryonic Skeletal System Development Lens Development In Camera-type Eye Cell Cycle Process Regulation Of Growth Signal Transduction Trachea Morphogenesis Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Embryonic Foregut Morphogenesis Regulation Of Gene Expression Foregut Morphogenesis Regulation Of Epithelial To Mesenchymal Transition Lung Development Negative Regulation Of Growth Negative Regulation Of Transcription From RNA Polymerase II Promoter Digestive Tract Morphogenesis Respiratory Tube Development Glycogen Metabolic Process Regulation Of Chondrocyte Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Signaling Skeletal System Morphogenesis Tube Morphogenesis Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Death	Signal Transduction Signaling Cell Communication Cellular Response To Stimulus Insulin Receptor Signaling Pathway Protein Autoubiquitination Cellular Response To Insulin Stimulus Response To Stimulus Response To Organic Substance Small GTPase Mediated Signal Transduction Intracellular Signal Transduction Cellular Response To Organic Substance Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Response To Insulin Response To Cytokine Regulation Of Cellular Protein Metabolic Process Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Regulation Of Protein Metabolic Process Cell Surface Receptor Signaling Pathway Cellular Response To Reactive Oxygen Species Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Cell Cycle Cytokine-mediated Signaling Pathway Response To Camptothecin Positive Regulation Of Anoikis Negative Regulation Of Cell Cycle Response To Peptide Hormone Cellular Response To Organonitrogen Compound Protein Heterooligomerization Response To Peptide Fatty Acid Biosynthetic Process Metabolic Process Cell Cycle Process Regulation Of Lipid Biosynthetic Process Negative Regulation Of Sphingolipid Biosynthetic Process Regulation Of Cellular Process Cell Cycle Arrest Regulation Of Protein Binding Negative Regulation Of Signal Transduction Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Transferase Activity Regulation Of Ceramide Biosynthetic Process Protein Ubiquitination Protein Polyubiquitination Negative Regulation Of Signaling
Tagcloud ?		calm3 cblb ccna2 ccnd3 cdk6 cited1 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 sh3kbp1 shc tgfbr1 tgfbr2 vav2 wilcoxon yes
Tagcloud (Difference) ?		calm3 cblb ccna2 ccnd3 cdk6 cited1 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 sh3kbp1 shc tgfbr1 tgfbr2 vav2 wilcoxon yes
Tagcloud (Intersection) ?