BAG6 and CSNK2B

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		BAG6	CSNK2B
Gene Name		BCL2-associated athanogene 6	casein kinase 2, beta polypeptide
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle BAT3 Complex	Nucleus Cytoplasm Cytosol Plasma Membrane Protein Kinase CK2 Complex PcG Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Hsp70 Protein Binding Polyubiquitin Binding Ubiquitin Protein Ligase Binding Ribosome Binding Proteasome Binding	Protein Serine/threonine Kinase Activity Receptor Binding Protein Binding Transcription Factor Binding Protein Kinase Regulator Activity Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Kidney Development Immune System Process Ubiquitin-dependent Protein Catabolic Process Transport Synaptonemal Complex Assembly Spermatogenesis Brain Development Embryo Development Chromatin Modification Internal Peptidyl-lysine Acetylation Cell Differentiation Lung Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of Proteolysis Protein Stabilization Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Tail-anchored Membrane Protein Insertion Into ER Membrane	Mitotic Cell Cycle Protein Phosphorylation Signal Transduction Axon Guidance Negative Regulation Of Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Wnt Signaling Pathway Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Negative Regulation Of Blood Vessel Endothelial Cell Migration Cellular Protein Complex Assembly Regulation Of Protein Kinase Activity Regulation Of DNA Binding Endothelial Tube Morphogenesis
Pathways			Mitotic Prometaphase Signal transduction by L1 Axon guidance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling L1CAM interactions Signaling by Wnt Cell Cycle, Mitotic M Phase WNT mediated activation of DVL TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by WNT in cancer Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS		Schizophrenia ( 23894747)
Protein-Protein Interactions		102 interactors: ACVR1B AMFR ANXA7 ARPC3 ATN1 ATXN2 B2M C1QA CD93 CDK16 CDK4 CDK5 CDKN1A CHN2 CLU CSNK2B CSTF2 CTCFL CTSB CTSE CTSL CXCL8 DNAJB11 DPT EDN1 EFEMP1 EFEMP2 EP300 FAM173A FAM46A FAM9B FAS FKBP2 FZD4 GADD45A GLRA2 GSK3B HSPA13 HSPA8 ICK IGF2 IGFBP5 IKBKAP IMMT IQCG KLHL12 LBP LPPR3 MAPK6 MAVS MEST MYDGF NBL1 NCR3 NDUFA6 NDUFB11 NOMO1 NPY NR1H2 PELP1 PIN1 PLA2G2A PLK1 POLR2J PPAP2C PRMT2 PRNP PRPF40A PTH PTN PTPN12 RAB8A RAC1 RCC1 RCN2 REG1B RNF126 S100A4 SDC2 SEC61A1 SEC61B SERPING1 SERPINH1 SETDB1 SGTA SMN1 SPP1 SRGN STX5 TAC1 TDGF1 TFCP2 TK1 TOMM20 TP63 TTR UBL4A UBL7 UBQLN4 VAMP2 XRN1 ZFYVE9	175 interactors: ABHD4 ACTB ACTL6B ACTR1B ACTR5 ACVRL1 ADD1 ADH5 ADRBK1 ANGPT2 ANKRD28 AP2M1 APLP1 ARAF ATF1 ATG101 ATXN3 BAG6 BCCIP BID BMI1 BRCA1 BTF3 C6orf136 C9orf114 CACNA1A CALM1 CBX4 CCDC115 CCNH CD163 CD81 CDC25B CDC34 CDK1 CDK20 CDKN1A CENPB CHEK1 CHRNA4 CIC COIL COL4A2 COPS2 COPS3 COPS7A CPNE7 CPSF3L CSN1S1 CSN2 CSNK2A1 CSNK2A2 CTDP1 CTNNB1 DACT1 DALRD3 DENND5A DNMT1 EIF2S2 EIF5 EIF6 EPS8 ERCC8 ESR1 FAF1 FBXL5 FGB FGF1 FGF2 FIBP FKBP3 FTH1 GADD45GIP1 GAMT GBP2 GLB1 GNB5 HEXB HIRIP3 HNRNPA2B1 HOXB6 HTRA1 IER3IP1 IRS1 ITSN1 JUN KDM6B KIF2C LCK LEPR LMO4 LRP5L LYN LYST MAPK14 MBD4 MGEA5 MME MOXD1 MPP2 NAP1L1 NCF1 NMT2 NOLC1 NOTCH3 NRBP1 ODC1 PDS5A PFKFB4 PHC2 PHF11 PHRF1 PIN1 PITPNA PLXNA3 POT1 PPID PPP3CC PRKAB2 PRKCZ PRNP PROC PTPRK PYROXD2 RFC1 RNF126 RNF7 RPA1 RPL13 RPL41 RPL5 RPS6KA2 RPS6KA5 RPS6KB1 RPS6KB2 RRAD RXRA SARNP SDHA SEC11A SHANK3 SHMT1 SHMT2 SIMC1 SIRT1 SNX2 SPSB3 SSB STAT5A STAU1 STK16 SUMO2 SYNE4 TCEAL7 TCTEX1D2 TLE1 TNFAIP1 TOP2B TP53 TP53BP2 TSEN54 TUBB2B UBE2I UPF1 USO1 UTP14A VDAC1 VRK3 WDR1 WDR18 WFIKKN1 ZNF44 ZNF71 ZNF784 ZNHIT1
Entrez ID		7917	1460
HPRD ID		00808	00278
Ensembl ID		ENSG00000204463	ENSG00000204435
Uniprot IDs		P46379	N0E4C7 P67870 Q5SRQ6
PDB IDs		1WX9 4DWF 4EEW	1DS5 1JWH 1QF8 3EED 4DGL
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Response To Stress Response To Stimulus Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Protein Phosphorylation Immune Response Regulation Of Immune System Process Regulation Of Protein Phosphorylation Cellular Response To Stimulus Defense Response Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Cell Cycle Response To External Stimulus Signal Transduction Developmental Process Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Positive Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cell Development System Development Regulation Of Phosphorylation Regulation Of Signal Transduction Response To Hormone Immune System Process Response To Lipid Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Protein Metabolic Process Regulation Of Cellular Process Cellular Process Regulation Of Catalytic Activity Response To Abiotic Stimulus Positive Regulation Of Metabolic Process Regulation Of Cell Motility Apoptotic Signaling Pathway Multicellular Organismal Development Positive Regulation Of Signal Transduction	Cellular Metabolic Process Response To Growth Factor Regulation Of Protein Metabolic Process Cellular Response To Growth Factor Stimulus Developmental Process Cellular Response To Organic Substance Regulation Of Cellular Protein Metabolic Process Cellular Protein Metabolic Process Multicellular Organismal Development Regulation Of Cell Proliferation Anatomical Structure Development Metabolic Process Response To Organic Substance Regulation Of Cellular Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Macromolecule Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Cycle Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process System Development Response To Stress Neurotrophin TRK Receptor Signaling Pathway Response To Stimulus Cell Cycle Positive Regulation Of Protein Metabolic Process Neurotrophin Signaling Pathway Nitrogen Compound Metabolic Process Biosynthetic Process Cellular Protein Modification Process Cellular Response To Stimulus Cell Death Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Death Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Radiation Response To Radiation Positive Regulation Of Cell Proliferation Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Process Cellular Response To Light Stimulus Gene Expression Regulation Of Phosphorylation Peptidyl-amino Acid Modification Programmed Cell Death Cellular Aromatic Compound Metabolic Process
Tagcloud ?		biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis
Tagcloud (Difference) ?		biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis
Tagcloud (Intersection) ?