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BAG6 and TTR
Number of citations of the paper that reports this interaction (PubMedID
26565908
)
0
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
BAG6
TTR
Description
BAG cochaperone 6
transthyretin
Image
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Extracellular Exosome
BAT3 Complex
Extracellular Region
Extracellular Space
Cytoplasm
Protein-containing Complex
Azurophil Granule Lumen
Extracellular Exosome
Molecular Function
Signaling Receptor Binding
Protein Binding
Hsp70 Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Ribosome Binding
Receptor Ligand Activity
Misfolded Protein Binding
Molecular Adaptor Activity
Proteasome Binding
Protein Carrier Chaperone
Ubiquitin-specific Protease Binding
Hormone Activity
Protein Binding
Hormone Binding
Identical Protein Binding
Protein-containing Complex Binding
Molecular Sequestering Activity
Biological Process
Kidney Development
Immune System Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Chromatin Organization
Ubiquitin-dependent Protein Catabolic Process
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Apoptotic Process
Synaptonemal Complex Assembly
Spermatogenesis
Brain Development
Proteasomal Protein Catabolic Process
Internal Peptidyl-lysine Acetylation
Natural Killer Cell Activation
Cell Differentiation
Lung Development
Regulation Of Protein Stability
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
ERAD Pathway
Maintenance Of Unfolded Protein
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteolysis
Regulation Of Embryonic Development
Protein Stabilization
NK T Cell Activation
Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Tail-anchored Membrane Protein Insertion Into ER Membrane
Positive Regulation Of ERAD Pathway
Retinoid Metabolic Process
Negative Regulation Of Glomerular Filtration
Purine Nucleobase Metabolic Process
Phototransduction, Visible Light
Pathways
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
The canonical retinoid cycle in rods (twilight vision)
Non-integrin membrane-ECM interactions
Neutrophil degranulation
Retinoid metabolism and transport
Amyloid fiber formation
Defective visual phototransduction due to STRA6 loss of function
Drugs
Zinc
Copper
Tafamidis
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Revusiran
Diseases
Familial carpal tunnel syndrome
Familial amyloidosis
GWAS
A body shape index (
34021172
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Height (
28552196
)
Hip circumference adjusted for BMI (
34021172
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Schizophrenia (
23894747
)
Small cell lung carcinoma (
28604730
)
Smoking status (ever vs never smokers) (
30643258
)
Ulcerative colitis (
28067908
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Retinol levels (
21878437
)
Interacting Genes
120 interacting genes:
ACVR1B
AKT1
AMFR
AMTN
ANTKMT
ANXA7
APBB1IP
ARPC3
ATN1
ATXN2
B2M
BCL2
C1QA
CD93
CDK16
CDK4
CDK5
CDKN1A
CDSN
CEBPA
CHN2
CILK1
CLU
CRIPTO
CSNK2B
CSTF2
CTAG1A
CTAG1B
CTCFL
CTSB
CTSE
CTSL
CXCL8
CYSRT1
DMKN
DNAJB11
DPT
DRC9
EDN1
EFEMP1
EFEMP2
ELP1
EP300
FAM9B
FAS
FKBP2
FZD4
GADD45A
GLRA2
GOLGA6L9
GSK3B
HSPA13
HSPA8
IGF2
IGFBP5
IMMT
KLHL12
KPNA2
LBP
MAP1LC3B
MAPK6
MECOM
MEST
MTNR1A
MYDGF
NBL1
NCR3
NDUFA6
NDUFB11
NOMO1
NPY
NR1H2
PELP1
PIN1
PLA2G2A
PLK1
PLPP2
PLPPR3
POLR2J
PRKAR1B
PRMT2
PRNP
PRPF40A
PTH
PTN
PTPN12
RAB8A
RAC1
RCC1
RCN2
REG1B
RNF126
S100A4
SDC2
SEC61A1
SEC61B
SERPING1
SERPINH1
SERPINI2
SETDB1
SGTA
SMN1
SPP1
SRGN
STX5
TAC1
TENT5A
TFCP2
TK1
TOMM20
TP53
TP63
TTR
UBL7
UBQLN1
UBQLN2
UBQLN4
VAMP2
XRN1
ZFYVE9
50 interacting genes:
A2M
ACTB
AGER
APOA1
ATF4
ATF5
BAG6
CDR2
CEP126
CFTR
CHD3
CLU
CPNE6
CTNND2
DDR1
EEF1A1
ELP1
ERG28
FEZ1
GET3
GET4
HNRNPH3
HSP90AA1
HSPG2
INPP5K
LRP2
MARK3
MT3
NDUFA5
NECAB2
NGFR
OTUB1
PHYHIP
PIK3R1
PRKCI
QARS1
RAI1
RBP4
RNF115
SDF4
SETDB1
SP110
ST13
ST3GAL3
SUMO3
TAF1C
TAF5L
TUBA1A
VIM
ZBED1
Entrez ID
7917
7276
HPRD ID
00808
01447
Ensembl ID
ENSG00000204463
ENSG00000118271
Uniprot IDs
A0A1U9X7A6
A0A7P0MQS5
P46379
E9KL36
P02766
PDB IDs
1WX9
2N9P
4DWF
4EEW
4WWR
4X86
6AU8
7RU9
7RUA
7RUC
1BM7
1BMZ
1BZ8
1BZD
1BZE
1DVQ
1DVS
1DVT
1DVU
1DVX
1DVY
1DVZ
1E3F
1E4H
1E5A
1ETA
1ETB
1F41
1F86
1FH2
1FHN
1G1O
1GKO
1ICT
1III
1IIK
1IJN
1QAB
1QWH
1RLB
1SOK
1SOQ
1THA
1THC
1TLM
1TSH
1TT6
1TTA
1TTB
1TTC
1TTR
1TYR
1TZ8
1U21
1X7S
1X7T
1Y1D
1Z7J
1ZCR
1ZD6
2B14
2B15
2B16
2B77
2B9A
2F7I
2F8I
2FBR
2FLM
2G3X
2G3Z
2G4E
2G4G
2G5U
2G9K
2GAB
2H4E
2M5N
2NBO
2NBP
2NOY
2PAB
2QEL
2QGB
2QGC
2QGD
2QGE
2ROX
2ROY
2TRH
2TRY
2WQA
3A4D
3A4E
3A4F
3B56
3BSZ
3BT0
3CBR
3CFM
3CFN
3CFQ
3CFT
3CN0
3CN1
3CN2
3CN3
3CN4
3CXF
3D2T
3D7P
3DGD
3DID
3DJR
3DJS
3DJT
3DJZ
3DK0
3DK2
3DO4
3ESN
3ESO
3ESP
3FC8
3FCB
3GLZ
3GPS
3GRB
3GRG
3GS0
3GS4
3GS7
3HJ0
3I9A
3I9I
3I9P
3IMR
3IMS
3IMT
3IMU
3IMV
3IMW
3IPB
3IPE
3KGS
3KGT
3KGU
3M1O
3NEE
3NEO
3NES
3NEX
3NG5
3OZK
3OZL
3P3R
3P3S
3P3T
3P3U
3SSG
3TCT
3TFB
3U2I
3U2J
3W3B
4ABQ
4ABU
4ABV
4ABW
4AC2
4AC4
4ACT
4ANK
4D7B
4DER
4DES
4DET
4DEU
4DEW
4FI6
4FI7
4FI8
4HIQ
4HIS
4HJS
4HJT
4HJU
4I85
4I87
4I89
4IIZ
4IK6
4IK7
4IKI
4IKJ
4IKK
4IKL
4KY2
4L1S
4L1T
4MAS
4MRB
4MRC
4N85
4N86
4N87
4PM1
4PME
4PMF
4PVL
4PVM
4PVN
4PWE
4PWF
4PWG
4PWH
4PWI
4PWJ
4PWK
4QRF
4QXV
4QYA
4TKW
4TL4
4TL5
4TLK
4TLS
4TLT
4TLU
4TM9
4TNE
4TNF
4TNG
4TQ8
4TQH
4TQI
4TQP
4WNJ
4WNS
4WO0
4Y9B
4Y9C
4Y9E
4Y9F
4Y9G
4YDM
4YDN
5A6I
5AKS
5AKT
5AKV
5AL0
5AL8
5AYT
5BOJ
5CLX
5CLY
5CLZ
5CM1
5CN3
5CNH
5CR1
5DEJ
5DWP
5E23
5E4A
5E4O
5EN3
5EZP
5FO2
5FW6
5FW7
5FW8
5H0V
5H0W
5H0X
5H0Y
5H0Z
5HJG
5IHH
5JID
5JIM
5JIQ
5K1J
5K1N
5L4F
5L4I
5L4J
5L4M
5LLL
5LLV
5N5Q
5N62
5N7C
5NFE
5NFW
5OQ0
5TTR
5TZL
5U48
5U49
5U4A
5U4B
5U4C
5U4D
5U4E
5U4F
5U4G
6D0W
6E6Z
6E70
6E71
6E72
6E73
6E74
6E75
6E76
6E77
6E78
6EOY
6EP1
6FFT
6FWD
6FXU
6FZL
6GR7
6GRP
6IMX
6IMY
6KGB
6R66
6R67
6R68
6R6I
6SDZ
6SUG
6SUH
6TI9
6TJN
6TXV
6TXW
6U0Q
6XTK
7ACU
7DT3
7DT5
7DT6
7DT8
7EJQ
7EJR
7ERH
7ERI
7ERJ
7ERK
7OB4
7Q3I
7Q9L
7Q9N
7Q9O
7QC5
7THA
7W9Q
7W9R
7WL6
7Y1I
7Y6J
7YBR
7YCQ
7Z60
8ADE
8AWI
8AWW
8C85
8C86
8E7D
8E7E
8E7H
8E7I
8E7J
8G9R
8GBR
8HEJ
8HY4
8I00
8I0O
8IG1
8II1
8II2
8II3
8II4
8JNU
8JOK
8JQW
8PKE
8PKF
8PKG
8PM8
8PM9
8PMA
8PMO
8T5X
8TDN
8TDO
8U52
8VE0
8VE1
8VE2
8VE3
8VE4
8VE5
8VE6
8W1N
8W2W
8W42
8W43
8W44
8W45
8W46
8W47
8W48
8WGS
8WGT
8WGU
8YQD
9BYN
9BZS
9H7A
9H7B
9H7C
9H7D
9H7E
9H7F
9H7G
9H7H
9H7I
9H7J
9H7K
9H7L
9H7M
9H7N
9H7O
9H7P
9JIQ
9JIR
9JIS
Enriched GO Terms of Interacting Partners
?
Regulation Of Cellular Response To Stress
Extracellular Space
Negative Regulation Of Multicellular Organismal Process
Regulation Of Proteolysis
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Extracellular Region
Protein Binding
Membrane Organization
Receptor Ligand Activity
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Response To Endoplasmic Reticulum Stress
Signal Transduction
Response To Hormone
Negative Regulation Of Proteolysis
Extracellular Matrix
Negative Regulation Of Cellular Component Organization
Response To Lipid
Tissue Development
Regulation Of Protein Catabolic Process
Tau Protein Binding
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Leukocyte Apoptotic Process
Positive Regulation Of Neutrophil Chemotaxis
Regulation Of Ossification
G1/S Transition Of Mitotic Cell Cycle
Protein-containing Complex
Establishment Of Protein Localization To Organelle
Molecular Function Activator Activity
Cell Cycle G1/S Phase Transition
Negative Regulation Of Developmental Process
Positive Regulation Of Granulocyte Chemotaxis
Regulation Of Multicellular Organismal Process
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cell Migration
Regulation Of Developmental Process
Response To Nutrient Levels
Cellular Response To Oxygen-containing Compound
Endoplasmic Reticulum Lumen
T Cell Apoptotic Process
Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Cell Cycle
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Cell Motility
Regulation Of Signal Transduction
Extracellular Exosome
Protein Carrier Chaperone
Amyloid-beta Binding
Tau Protein Binding
Tail-anchored Membrane Protein Insertion Into ER Membrane
Positive Regulation Of Transport
Cytoplasm
BAT3 Complex
Regulation Of Protein Localization
Maintenance Of Unfolded Protein
Protein Stabilization
Protein Binding
Regulation Of Protein Stability
Protein Insertion Into ER Membrane
Regulation Of Protein Localization To Nucleus
Regulation Of Macromolecule Metabolic Process
Regulation Of Cellular Localization
Regulation Of Primary Metabolic Process
Negative Regulation Of Neuron Apoptotic Process
Regulation Of Cellular Response To Stress
Axon
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Cellular Response To Oxygen-containing Compound
Negative Regulation Of Cellular Component Organization
Cell Projection
Regulation Of Programmed Cell Death
Nitric-oxide Synthase Regulator Activity
Regulation Of Metabolic Process
Cell Projection Organization
Spherical High-density Lipoprotein Particle
Sterol Biosynthetic Process
Negative Regulation Of Programmed Cell Death
Protein-folding Chaperone Binding
Vitamin Transport
Positive Regulation Of Protein Localization
Carbohydrate Homeostasis
Glucose Homeostasis
Vagina Development
Blood Microparticle
Cellular Response To Amyloid-beta
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Brush Border
Regulation Of Multicellular Organismal Development
Response To Endoplasmic Reticulum Stress
Circadian Rhythm
Kinase Activator Activity
ATP Hydrolysis Activity
Developmental Process
Negative Regulation Of Complement Activation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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