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BAG6 and PRKAR1B
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
BAG6
PRKAR1B
Description
BAG cochaperone 6
protein kinase cAMP-dependent type I regulatory subunit beta
Image
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Extracellular Exosome
BAT3 Complex
Cytoplasm
Multivesicular Body
Cytosol
Plasma Membrane
CAMP-dependent Protein Kinase Complex
Membrane
Synapse
Ciliary Base
Schaffer Collateral - CA1 Synapse
Hippocampal Mossy Fiber To CA3 Synapse
Postsynapse
Glutamatergic Synapse
Molecular Function
Signaling Receptor Binding
Protein Binding
Hsp70 Protein Binding
Polyubiquitin Modification-dependent Protein Binding
Ubiquitin Protein Ligase Binding
Identical Protein Binding
Ribosome Binding
Receptor Ligand Activity
Misfolded Protein Binding
Molecular Adaptor Activity
Proteasome Binding
Protein Carrier Chaperone
Ubiquitin-specific Protease Binding
Nucleotide Binding
CAMP-dependent Protein Kinase Inhibitor Activity
Protein Binding
CAMP-dependent Protein Kinase Regulator Activity
CAMP Binding
Protein Kinase A Catalytic Subunit Binding
Biological Process
Kidney Development
Immune System Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Chromatin Organization
Ubiquitin-dependent Protein Catabolic Process
Post-translational Protein Targeting To Endoplasmic Reticulum Membrane
Apoptotic Process
Synaptonemal Complex Assembly
Spermatogenesis
Brain Development
Proteasomal Protein Catabolic Process
Internal Peptidyl-lysine Acetylation
Natural Killer Cell Activation
Cell Differentiation
Lung Development
Regulation Of Protein Stability
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
ERAD Pathway
Maintenance Of Unfolded Protein
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteolysis
Regulation Of Embryonic Development
Protein Stabilization
NK T Cell Activation
Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Tail-anchored Membrane Protein Insertion Into ER Membrane
Positive Regulation Of ERAD Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Learning Or Memory
Modulation Of Chemical Synaptic Transmission
Regulation Of Synaptic Vesicle Cycle
Negative Regulation Of CAMP/PKA Signal Transduction
Positive Regulation Of Long-term Synaptic Potentiation
Positive Regulation Of Fear Response
Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Vasopressin regulates renal water homeostasis via Aquaporins
CREB1 phosphorylation through the activation of Adenylate Cyclase
Hedgehog 'off' state
GPER1 signaling
ADORA2B mediated anti-inflammatory cytokines production
FCGR3A-mediated IL10 synthesis
Factors involved in megakaryocyte development and platelet production
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs
Diseases
GWAS
A body shape index (
34021172
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Height (
28552196
)
Hip circumference adjusted for BMI (
34021172
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Schizophrenia (
23894747
)
Small cell lung carcinoma (
28604730
)
Smoking status (ever vs never smokers) (
30643258
)
Ulcerative colitis (
28067908
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Body size at age 10 (
32376654
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
Hematocrit (
27863252
32888494
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Plasma free amino acid levels (
30659259
)
Red blood cell count (
27863252
32888494
)
Interacting Genes
120 interacting genes:
ACVR1B
AKT1
AMFR
AMTN
ANTKMT
ANXA7
APBB1IP
ARPC3
ATN1
ATXN2
B2M
BCL2
C1QA
CD93
CDK16
CDK4
CDK5
CDKN1A
CDSN
CEBPA
CHN2
CILK1
CLU
CRIPTO
CSNK2B
CSTF2
CTAG1A
CTAG1B
CTCFL
CTSB
CTSE
CTSL
CXCL8
CYSRT1
DMKN
DNAJB11
DPT
DRC9
EDN1
EFEMP1
EFEMP2
ELP1
EP300
FAM9B
FAS
FKBP2
FZD4
GADD45A
GLRA2
GOLGA6L9
GSK3B
HSPA13
HSPA8
IGF2
IGFBP5
IMMT
KLHL12
KPNA2
LBP
MAP1LC3B
MAPK6
MECOM
MEST
MTNR1A
MYDGF
NBL1
NCR3
NDUFA6
NDUFB11
NOMO1
NPY
NR1H2
PELP1
PIN1
PLA2G2A
PLK1
PLPP2
PLPPR3
POLR2J
PRKAR1B
PRMT2
PRNP
PRPF40A
PTH
PTN
PTPN12
RAB8A
RAC1
RCC1
RCN2
REG1B
RNF126
S100A4
SDC2
SEC61A1
SEC61B
SERPING1
SERPINH1
SERPINI2
SETDB1
SGTA
SMN1
SPP1
SRGN
STX5
TAC1
TENT5A
TFCP2
TK1
TOMM20
TP53
TP63
TTR
UBL7
UBQLN1
UBQLN2
UBQLN4
VAMP2
XRN1
ZFYVE9
75 interacting genes:
AKAP1
AKAP14
ANKS1A
BAG3
BAG6
BOD1L2
CAMSAP1
CBX8
CCDC187
CDC37
CDKN1A
CEP19
COX5B
DACH1
DNAAF19
DTNB
EEF2KMT
EGFR
FAM161A
FAM90A1
FCHSD2
GAS2L2
GLIS2
GNL3L
GOLGA1
GPKOW
GUCA1A
IGFN1
INPP5J
KANK2
KIF5B
L3MBTL2
LENG1
LNX1
MBD3
MED8
MYO15B
NTAQ1
NXF1
PIK3R3
POLE4
PPP1R9A
PRKAA2
PRKAR1A
PRPF18
PSMG1
QRICH1
RARG
RUNX1T1
SAP30BP
SH2D4A
SHC3
SMAD3
SMAD4
SMG9
SNW1
STK16
SYTL4
TASOR2
TEAD4
THRA
TSGA10IP
UACA
UBC
VEZF1
WNK1
WRN
ZBTB16
ZMYND19
ZNF177
ZNF329
ZNF35
ZNF410
ZNF559-ZNF177
ZNF76
Entrez ID
7917
5575
HPRD ID
00808
01485
Ensembl ID
ENSG00000204463
ENSG00000188191
Uniprot IDs
A0A1U9X7A6
A0A7P0MQS5
P46379
P31321
PDB IDs
1WX9
2N9P
4DWF
4EEW
4WWR
4X86
6AU8
7RU9
7RUA
7RUC
4DIN
4F9K
Enriched GO Terms of Interacting Partners
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Regulation Of Cellular Response To Stress
Extracellular Space
Negative Regulation Of Multicellular Organismal Process
Regulation Of Proteolysis
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Proteasomal Protein Catabolic Process
Extracellular Region
Protein Binding
Membrane Organization
Receptor Ligand Activity
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Response To Endoplasmic Reticulum Stress
Signal Transduction
Response To Hormone
Negative Regulation Of Proteolysis
Extracellular Matrix
Negative Regulation Of Cellular Component Organization
Response To Lipid
Tissue Development
Regulation Of Protein Catabolic Process
Tau Protein Binding
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Catabolic Process
Leukocyte Apoptotic Process
Positive Regulation Of Neutrophil Chemotaxis
Regulation Of Ossification
G1/S Transition Of Mitotic Cell Cycle
Protein-containing Complex
Establishment Of Protein Localization To Organelle
Molecular Function Activator Activity
Cell Cycle G1/S Phase Transition
Negative Regulation Of Developmental Process
Positive Regulation Of Granulocyte Chemotaxis
Regulation Of Multicellular Organismal Process
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cell Migration
Regulation Of Developmental Process
Response To Nutrient Levels
Cellular Response To Oxygen-containing Compound
Endoplasmic Reticulum Lumen
T Cell Apoptotic Process
Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Cell Cycle
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Cell Motility
Regulation Of Signal Transduction
Protein Binding
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleoplasm
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of RNA Biosynthetic Process
Apoptotic Signaling Pathway
Ciliary Basal Body
Negative Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Protein Localization
Retinoic Acid Receptor Signaling Pathway
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
SMAD Protein Complex
Protein Folding Chaperone Complex
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Heteromeric SMAD Protein Complex
Regulation Of Transforming Growth Factor Beta2 Production
Regulation Of Macromolecule Biosynthetic Process
DNA Binding
Zinc Ion Binding
Nuclear Speck
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Intracellular Signal Transduction
DNA-binding Transcription Factor Activity
In Utero Embryonic Development
Regulation Of Gene Expression
Chordate Embryonic Development
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Extracellular Matrix Assembly
CAMP-dependent Protein Kinase Complex
Protein Carrier Chaperone
Regulation Of Vitamin D Receptor Signaling Pathway
Regulation Of Primary Metabolic Process
Cytoplasm
Nucleus
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Tagcloud (Intersection)
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