BAG6 and CTSE

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BAG6	CTSE
Gene Name		BCL2-associated athanogene 6	cathepsin E
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle BAT3 Complex	Endosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Hsp70 Protein Binding Polyubiquitin Binding Ubiquitin Protein Ligase Binding Ribosome Binding Proteasome Binding	Aspartic-type Endopeptidase Activity Protein Homodimerization Activity
	Biological Process	Kidney Development Immune System Process Ubiquitin-dependent Protein Catabolic Process Transport Synaptonemal Complex Assembly Spermatogenesis Brain Development Embryo Development Chromatin Modification Internal Peptidyl-lysine Acetylation Cell Differentiation Lung Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of Proteolysis Protein Stabilization Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Tail-anchored Membrane Protein Insertion Into ER Membrane	Proteolysis Digestion Protein Autoprocessing Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways			MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Schizophrenia ( 23894747)
Protein-Protein Interactions		102 interactors: ACVR1B AMFR ANXA7 ARPC3 ATN1 ATXN2 B2M C1QA CD93 CDK16 CDK4 CDK5 CDKN1A CHN2 CLU CSNK2B CSTF2 CTCFL CTSB CTSE CTSL CXCL8 DNAJB11 DPT EDN1 EFEMP1 EFEMP2 EP300 FAM173A FAM46A FAM9B FAS FKBP2 FZD4 GADD45A GLRA2 GSK3B HSPA13 HSPA8 ICK IGF2 IGFBP5 IKBKAP IMMT IQCG KLHL12 LBP LPPR3 MAPK6 MAVS MEST MYDGF NBL1 NCR3 NDUFA6 NDUFB11 NOMO1 NPY NR1H2 PELP1 PIN1 PLA2G2A PLK1 POLR2J PPAP2C PRMT2 PRNP PRPF40A PTH PTN PTPN12 RAB8A RAC1 RCC1 RCN2 REG1B RNF126 S100A4 SDC2 SEC61A1 SEC61B SERPING1 SERPINH1 SETDB1 SGTA SMN1 SPP1 SRGN STX5 TAC1 TDGF1 TFCP2 TK1 TOMM20 TP63 TTR UBL4A UBL7 UBQLN4 VAMP2 XRN1 ZFYVE9	5 interactors: A2M BAG6 EDN3 EMG1 INS
Entrez ID		7917	1510
HPRD ID		00808	00294
Ensembl ID		ENSG00000204463	ENSG00000196188
Uniprot IDs		P46379	P14091
PDB IDs		1WX9 4DWF 4EEW	1LCG 1TZS
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Response To Stress Response To Stimulus Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Protein Phosphorylation Immune Response Regulation Of Immune System Process Regulation Of Protein Phosphorylation Cellular Response To Stimulus Defense Response Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Cell Cycle Response To External Stimulus Signal Transduction Developmental Process Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Positive Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cell Development System Development Regulation Of Phosphorylation Regulation Of Signal Transduction Response To Hormone Immune System Process Response To Lipid Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Protein Metabolic Process Regulation Of Cellular Process Cellular Process Regulation Of Catalytic Activity Response To Abiotic Stimulus Positive Regulation Of Metabolic Process Regulation Of Cell Motility Apoptotic Signaling Pathway Multicellular Organismal Development Positive Regulation Of Signal Transduction	Negative Regulation Of Innate Immune Response Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Processing Regulation Of Acute Inflammatory Response Intracellular Signal Transduction Positive Regulation Of Hormone Secretion Regulation Of Proteolysis Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Positive Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Nuclear Division Positive Regulation Of Cell Division Negative Regulation Of Immune Response Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Glycogen Catabolic Process Negative Regulation Of Complement Activation, Lectin Pathway Negative Regulation Of Protein Metabolic Process Negative Regulation Of Respiratory Burst Involved In Inflammatory Response Negative Regulation Of NAD(P)H Oxidase Activity Regulation Of Behavior Vein Smooth Muscle Contraction Positive Regulation Of Cell Cycle Process Regulation Of Systemic Arterial Blood Pressure By Endothelin Regulation Of Innate Immune Response Regulation Of Cell Division Positive Regulation Of Brown Fat Cell Differentiation Regulation Of Hormone Secretion Regulation Of Brown Fat Cell Differentiation Cellular Magnesium Ion Homeostasis Regulation Of NAD(P)H Oxidase Activity Negative Regulation Of Feeding Behavior Tail-anchored Membrane Protein Insertion Into ER Membrane Regulation Of Inflammatory Response Positive Regulation Of Cell Cycle Regulation Of Immune System Process Positive Regulation Of Respiratory Burst Negative Regulation Of Vasodilation Stem Cell Differentiation Protein Insertion Into ER Membrane Positive Regulation Of Secretion Positive Regulation Of Cell Migration Negative Regulation Of Protein Oligomerization Regulation Of Glycogen Catabolic Process Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Cell Proliferation
Tagcloud ?		biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Difference) ?		biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Intersection) ?