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ZFYVE9 and RHOT2
Number of citations of the paper that reports this interaction (PubMedID
15231748
)
54
Data Source:
HPRD
(two hybrid)
ZFYVE9
RHOT2
Description
zinc finger FYVE-type containing 9
ras homolog family member T2
Image
GO Annotations
Cellular Component
Cytoplasm
Endosome
Early Endosome
Cytosol
Membrane
Early Endosome Membrane
Protein-containing Complex
Mitochondrion
Mitochondrial Outer Membrane
Membrane
Molecular Function
Protein Binding
1-phosphatidylinositol Binding
Zinc Ion Binding
Protein Domain Specific Binding
Metal Ion Binding
Nucleotide Binding
Magnesium Ion Binding
GTPase Activity
Calcium Ion Binding
Protein Binding
GTP Binding
Hydrolase Activity
ATP Hydrolysis Activity
GDP Binding
Metal Ion Binding
Biological Process
Endocytosis
Transforming Growth Factor Beta Receptor Signaling Pathway
Endosomal Transport
Mitochondrion Organization
Cellular Homeostasis
Mitochondrion Transport Along Microtubule
Mitochondrial Outer Membrane Permeabilization
Pathways
RHOT2 GTPase cycle
RHOT2 GTPase cycle
Drugs
Diseases
GWAS
Hip circumference adjusted for BMI (
34021172
)
Body mass index (
26426971
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Hip circumference adjusted for BMI (
34021172
)
Red blood cell traits (
23446634
)
Interacting Genes
38 interacting genes:
ANKLE2
BAG6
BMP4
CHD6
CLTC
CTNNB1
DAZAP2
EIF4G1
ERBIN
ETS2
FHL2
JUP
LRP12
NIT1
NUP155
PML
PPP1CA
PPP1CB
PPP1CC
PPP2R1A
RBBP6
RHOT2
RNF11
RNPEP
SCYL2
SMAD2
SMAD3
SPART
ST7
SUMF2
SUPT5H
SVEP1
TENT5A
TGFBR1
TGFBR2
UBC
UBXN11
ZMYND8
5 interacting genes:
PRKN
SAR1A
TMEM14B
TMEM86B
ZFYVE9
Entrez ID
9372
89941
HPRD ID
04782
15248
Ensembl ID
ENSG00000157077
ENSG00000140983
Uniprot IDs
O95405
A0A8V8TM48
Q8IXI1
PDB IDs
1DEV
1MK2
4BKW
5MJY
5KUT
Enriched GO Terms of Interacting Partners
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Embryonic Cranial Skeleton Morphogenesis
Positive Regulation Of Epithelial To Mesenchymal Transition
Ubiquitin Protein Ligase Binding
Embryonic Skeletal System Morphogenesis
I-SMAD Binding
SMAD Binding
Lung Development
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Regulation Of Epithelial To Mesenchymal Transition
Skeletal System Morphogenesis
Entrainment Of Circadian Clock By Photoperiod
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
SMAD Protein Signal Transduction
Trachea Formation
Trophoblast Cell Migration
PTW/PP1 Phosphatase Complex
Embryonic Organ Morphogenesis
Photoperiodism
Entrainment Of Circadian Clock
Activin Receptor Signaling Pathway
Embryonic Foregut Morphogenesis
Enzyme-linked Receptor Protein Signaling Pathway
Positive Regulation Of SMAD Protein Signal Transduction
Cell Fate Commitment
Tissue Morphogenesis
Transforming Growth Factor Beta Receptor Signaling Pathway
Tissue Development
Gastrulation
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Branching Involved In Lung Morphogenesis
Tube Morphogenesis
Positive Regulation Of Developmental Process
Regulation Of Chondrocyte Differentiation
Positive Regulation Of Transcription Elongation By RNA Polymerase II
Mesenchyme Development
Regulation Of Developmental Process
Formation Of Primary Germ Layer
Branching Morphogenesis Of An Epithelial Tube
Osteoblast Differentiation
Bronchus Development
Animal Organ Formation
Positive Regulation Of DNA-templated Transcription, Elongation
Catenin-TCF7L2 Complex
Paraxial Mesoderm Morphogenesis
Transforming Growth Factor Beta Ligand-receptor Complex
Regulation Of Translation In Response To Stress
Circadian Regulation Of Gene Expression
In Utero Embryonic Development
Regulation Of SMAD Protein Signal Transduction
Developmental Growth
Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex
Positive Regulation Of Retrograde Transport, Endosome To Golgi
Negative Regulation Of Glucokinase Activity
Regulation Protein Catabolic Process At Presynapse
Negative Regulation Of Intralumenal Vesicle Formation
Mitochondrion To Lysosome Vesicle-mediated Transport
Mitochondrion-derived Vesicle
F-box Domain Binding
Positive Regulation Of Protein Linear Polyubiquitination
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Cellular Response To Hydrogen Sulfide
Negative Regulation Of Spontaneous Neurotransmitter Secretion
Response To Curcumin
Amino Acid Sensor Activity
D-lysine 5,6-aminomutase Activity
Ether Hydrolase Activity
Alkenylglycerophosphocholine Hydrolase Activity
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Central Nervous System Development
Positive Regulation Of Mitochondrial Fusion
Cellular Response To L-glutamine
Response To Hydrogen Sulfide
Negative Regulation Of Exosomal Secretion
Lewy Body
Regulation Of Spontaneous Synaptic Transmission
Type 2 Mitophagy
Dopamine Uptake Involved In Synaptic Transmission
Negative Regulation Of Mitochondrial Fission
Regulation Of Endosome Organization
Positive Regulation Of Mitochondrial Membrane Potential
Aggresome Assembly
Positive Regulation Of Neurotransmitter Uptake
Regulation Of Synaptic Vesicle Transport
Regulation Of COPII Vesicle Coating
Free Ubiquitin Chain Polymerization
Cellular Response To Dopamine
Negative Regulation Of Mitochondrial Fusion
Negative Regulation Of Neurotransmitter Secretion
Regulation Of Retrograde Transport, Endosome To Golgi
Identical Protein Binding
Response To Dopamine
Negative Regulation Of Synaptic Transmission, Glutamatergic
Cellular Response To L-glutamate
Inclusion Body Assembly
Cellular Response To Manganese Ion
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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