ZFYVE9 and ZMYND8

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		ZFYVE9	ZMYND8
Gene Name		zinc finger, FYVE domain containing 9	zinc finger, MYND-type containing 8
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Early Endosome Membrane	Nucleus
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Serine-type Peptidase Activity Metal Ion Binding	RNA Polymerase II Transcription Corepressor Activity Protein Binding Zinc Ion Binding Repressing Transcription Factor Binding
	Biological Process	Proteolysis Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway SMAD Protein Complex Assembly SMAD Protein Import Into Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Negative Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBB2IP ETS2 FAM46A FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPG20 ST7 SUMF2 SUPT5H SVEP1 TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	9 interactors: ATN1 CSNK1E FHOD1 PBXIP1 PRKCB RERE USP7 ZBTB7A ZFYVE9
Entrez ID		9372	23613
HPRD ID		04782	10166
Ensembl ID		ENSG00000157077	ENSG00000101040
Uniprot IDs		O95405	A6H8Y8 B7Z2A8 B7ZM62 F5H0X3 H7C0U2 J3KPU3 Q2HXV1 Q2HXV3 Q2HXV5 Q569J9 Q9ULU4
PDB IDs		1DEV 1MK2 4BKW
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Common-partner SMAD Protein Phosphorylation Cell Cycle Trachea Formation Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Embryonic Skeletal System Morphogenesis Entrainment Of Circadian Clock By Photoperiod Embryonic Cranial Skeleton Morphogenesis Cellular Response To Organic Substance Response To Organic Substance Photoperiodism Entrainment Of Circadian Clock Embryonic Skeletal System Development Lens Development In Camera-type Eye Cell Cycle Process Regulation Of Growth Signal Transduction Trachea Morphogenesis Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Embryonic Foregut Morphogenesis Regulation Of Gene Expression Foregut Morphogenesis Regulation Of Epithelial To Mesenchymal Transition Lung Development Negative Regulation Of Growth Negative Regulation Of Transcription From RNA Polymerase II Promoter Digestive Tract Morphogenesis Respiratory Tube Development Glycogen Metabolic Process Regulation Of Chondrocyte Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Signaling Skeletal System Morphogenesis Tube Morphogenesis Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Death	Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Histone H3-T6 Phosphorylation Protein Import Into Nucleus Nuclear Import Chromatin Modification Protein Import Protein Localization To Nucleus Chromatin Organization Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cellular Process Regulation Of Proteasomal Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Maintenance Of DNA Methylation Heterocycle Metabolic Process SMAD Protein Import Into Nucleus Positive Regulation Of B Cell Receptor Signaling Pathway Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Protein Localization Cellular Nitrogen Compound Metabolic Process Nucleocytoplasmic Transport Nuclear Transport SMAD Protein Complex Assembly Maintenance Of Cell Polarity Toxin Metabolic Process Chromosome Organization Negative Regulation Of Glucose Transport Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization To Organelle Transcription, DNA-templated Histone Deubiquitination Lipoprotein Transport NLS-bearing Protein Import Into Nucleus Negative Regulation Of Signaling RNA Biosynthetic Process Regulation Of Protein Catabolic Process Histone Modification
Tagcloud ?		calm3 cblb ccna2 ccnd3 cdk6 cited1 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 sh3kbp1 shc tgfbr1 tgfbr2 vav2 wilcoxon yes
Tagcloud (Difference) ?		calm3 cblb ccna2 ccnd3 cdk6 cited1 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 sh3kbp1 shc tgfbr1 tgfbr2 vav2 wilcoxon yes
Tagcloud (Intersection) ?