ZFYVE9 and ST7

Number of citations of the paper that reports this interaction (PMID 12809483)
4

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ZFYVE9	ST7
Gene Name		zinc finger, FYVE domain containing 9	suppression of tumorigenicity 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Early Endosome Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Serine-type Peptidase Activity Metal Ion Binding
	Biological Process	Proteolysis Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway SMAD Protein Complex Assembly SMAD Protein Import Into Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
Protein-Protein Interactions		38 interactors: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBB2IP ETS2 FAM46A FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPG20 ST7 SUMF2 SUPT5H SVEP1 TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	7 interactors: ACTN2 GNB2L1 MYOT NFKBIA NMRK2 SNAPIN ZFYVE9
Entrez ID		9372	7982
HPRD ID		04782	09015
Ensembl ID		ENSG00000157077	ENSG00000004866
Uniprot IDs		O95405	Q9NRC1
PDB IDs		1DEV 1MK2 4BKW
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Common-partner SMAD Protein Phosphorylation Cell Cycle Trachea Formation Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Embryonic Skeletal System Morphogenesis Entrainment Of Circadian Clock By Photoperiod Embryonic Cranial Skeleton Morphogenesis Cellular Response To Organic Substance Response To Organic Substance Photoperiodism Entrainment Of Circadian Clock Embryonic Skeletal System Development Lens Development In Camera-type Eye Cell Cycle Process Regulation Of Growth Signal Transduction Trachea Morphogenesis Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Embryonic Foregut Morphogenesis Regulation Of Gene Expression Foregut Morphogenesis Regulation Of Epithelial To Mesenchymal Transition Lung Development Negative Regulation Of Growth Negative Regulation Of Transcription From RNA Polymerase II Promoter Digestive Tract Morphogenesis Respiratory Tube Development Glycogen Metabolic Process Regulation Of Chondrocyte Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Signaling Skeletal System Morphogenesis Tube Morphogenesis Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Death	Regulation Of Cellular Localization Negative Regulation Of Transport Positive Regulation Of Late Endosome To Lysosome Transport Viral Process Protein Import Into Nucleus Nuclear Import Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Positive Regulation Of CAMP Catabolic Process Cytoplasmic Transport Terminal Button Organization Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Autophagic Vacuole Maturation Protein Import Negative Regulation Of Cell Differentiation Positive Regulation Of Transport Protein Localization To Nucleus Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Protein Localization Establishment Of Localization In Cell Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cytoplasmic Sequestering Of NF-kappaB Microspike Assembly Muscle Contraction Intracellular Protein Transport Cellular Response To Cold Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Binding Negative Regulation Of Protein Localization To Cell Surface SMAD Protein Import Into Nucleus Muscle System Process Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Protein Homooligomerization Positive Regulation Of Gastrulation Cellular Localization Negative Regulation Of Signal Transduction Negative Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Mitochondrial Depolarization Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Hydrogen Peroxide-induced Cell Death SMAD Protein Complex Assembly Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Phagocytosis Negative Regulation Of Signaling Synaptic Vesicle Maturation Exocytosis Negative Regulation Of Potassium Ion Transmembrane Transport Establishment Of Protein Localization To Organelle Negative Regulation Of Macrophage Derived Foam Cell Differentiation
Tagcloud ?		calm3 cblb ccna2 ccnd3 cdk6 cited1 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 sh3kbp1 shc tgfbr1 tgfbr2 vav2 wilcoxon yes	acupuncture analog ashi cm2 delivered diode endpoint examinations gaalas handylaser improves ineffective j laser li4 mmo mouth mw opening palpation pulsed rest sessions st6 temporomandibular tmd trion vas waves
Tagcloud (Difference) ?		calm3 cblb ccna2 ccnd3 cdk6 cited1 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 sh3kbp1 shc tgfbr1 tgfbr2 vav2 wilcoxon yes	acupuncture analog ashi cm2 delivered diode endpoint examinations gaalas handylaser improves ineffective j laser li4 mmo mouth mw opening palpation pulsed rest sessions st6 temporomandibular tmd trion vas waves
Tagcloud (Intersection) ?