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PDLIM1 and ACTN1
Number of citations of the paper that reports this interaction (PMID
11110697
)
22
Data Source:
HPRD
(in vivo, in vitro, two hybrid)
PDLIM1
ACTN1
Gene Name
PDZ and LIM domain 1
actinin, alpha 1
Image
Gene Ontology Annotations
Cellular Component
Transcription Factor Complex
Cytoplasm
Cytoskeleton
Focal Adhesion
Stress Fiber
Ruffle
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Fascia Adherens
Focal Adhesion
Z Disc
Cortical Actin Cytoskeleton
Platelet Alpha Granule Lumen
Pseudopodium
Cell Projection
Dendritic Spine
Extracellular Vesicular Exosome
Molecular Function
Transcription Coactivator Activity
Zinc Ion Binding
Double-stranded RNA Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Vinculin Binding
Protein Domain Specific Binding
Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Ion Channel Binding
Actin Filament Binding
Biological Process
Response To Hypoxia
Regulation Of Transcription, DNA-templated
Response To Oxidative Stress
Platelet Degranulation
Blood Coagulation
Platelet Activation
Extracellular Matrix Organization
Cell Junction Assembly
Regulation Of Apoptotic Process
Focal Adhesion Assembly
Actin Filament Bundle Assembly
Negative Regulation Of Cellular Component Movement
Actin Crosslink Formation
Regulation Of Nucleic Acid-templated Transcription
Pathways
Cell junction organization
Syndecan interactions
Response to elevated platelet cytosolic Ca2+
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Nephrin interactions
Platelet degranulation
Non-integrin membrane-ECM interactions
Platelet activation, signaling and aggregation
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Smoking behavior (
19247474
)
Protein-Protein Interactions
13 interactors:
ACTN1
ACTN2
ACTN4
AGK
GFAP
MAPK6
PGS1
PITX2
RLIM
RPS6KA5
STK35
SUPT4H1
VIM
70 interactors:
ACTN3
ADORA2A
APC
ATXN2
ATXN7
CACNA1A
CAMK2A
CDK5
CDK5R1
CDK5R2
CLIC5
COIL
COL17A1
CSRP1
CSRP3
CTNNA1
EPM2AIP1
ERBB2IP
FBP1
FXN
GFI1B
GIPC1
GIT2
GRIA4
GRIN2A
GTF2H1
ITGB1
KAT2B
KCTD6
KPNA2
LPP
MAGEA11
MAP2
MAP3K1
MED14
MICALL2
MYOT
MYOZ1
MYOZ2
MYOZ3
NEBL
NR1H3
NUMBL
OAS1
PALLD
PDHX
PDLIM1
PDLIM5
PIAS4
PKD1
PKN1
PLD2
PSEN1
PSMA1
PTK2
PTPN1
PTPN6
PYGB
RAVER1
RPS27
SLC2A4
SORBS2
SPERT
SRC
SSX2IP
TES
TTN
VCL
XRCC4
ZYX
Entrez ID
9124
87
HPRD ID
09326
00020
Ensembl ID
ENSG00000107438
ENSG00000072110
Uniprot IDs
O00151
P12814
PDB IDs
1X62
2PKT
2EYI
2EYN
Enriched GO Terms of Interacting Partners
?
Protein Localization To Tight Junction
Bergmann Glial Cell Differentiation
Protein Localization To Cell Junction
Platelet Degranulation
Intermediate Filament Organization
Actin Crosslink Formation
Astrocyte Development
Actin-myosin Filament Sliding
Focal Adhesion Assembly
Muscle Filament Sliding
Platelet Activation
Cell Junction Assembly
Cell-cell Junction Organization
Intermediate Filament Cytoskeleton Organization
Astrocyte Differentiation
Intermediate Filament-based Process
Actin-mediated Cell Contraction
Tight Junction Assembly
Adherens Junction Assembly
Actin Filament-based Process
Positive Regulation Of Ion Transmembrane Transporter Activity
Cell-substrate Junction Assembly
Response To Wounding
Positive Regulation Of Transporter Activity
Actin Filament Bundle Assembly
Actin Filament-based Movement
Histone H2A-S1 Phosphorylation
Subthalamic Nucleus Development
Prolactin Secreting Cell Differentiation
Random Inactivation Of X Chromosome
Positive Regulation Of Schwann Cell Proliferation
Superior Vena Cava Morphogenesis
Apical Junction Assembly
Exocytosis
Positive Regulation Of Ion Transmembrane Transport
Adherens Junction Organization
Cell Proliferation Involved In Outflow Tract Morphogenesis
Subthalamus Development
Left Lung Morphogenesis
Pulmonary Vein Morphogenesis
Blood Coagulation
Glial Cell Development
Hemostasis
Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis
Extraocular Skeletal Muscle Development
Pulmonary Myocardium Development
Positive Regulation Of Pinocytosis
Left Lung Development
Cell-cell Junction Assembly
Negative Regulation Of Neuron Projection Development
Cytoskeleton Organization
Cell Adhesion
Cellular Component Assembly
Organelle Organization
Cell Development
Regulation Of Protein Kinase Activity
Actin Filament-based Process
Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Actin Cytoskeleton Organization
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Metabolic Process
Cell-substrate Adhesion
Anatomical Structure Morphogenesis
Neurogenesis
Regulation Of Phosphorus Metabolic Process
Cell Differentiation
Generation Of Neurons
Cell Morphogenesis
Regulation Of Protein Phosphorylation
Response To Stress
Actomyosin Structure Organization
Neuron Development
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Catalytic Activity
Central Nervous System Development
Positive Regulation Of Transferase Activity
Regulation Of Signaling
Response To Stimulus
Response To Wounding
Regulation Of Phosphorylation
Cell-cell Junction Organization
Regulation Of Cell Projection Organization
Nervous System Development
Anatomical Structure Formation Involved In Morphogenesis
Single Organismal Cell-cell Adhesion
Adherens Junction Organization
Neuron Projection Development
Neuron Differentiation
Anatomical Structure Development
Blood Coagulation
Cell Surface Receptor Signaling Pathway
Cell Projection Organization
Hemostasis
Cell-matrix Adhesion
Apical Junction Assembly
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Signal Transduction
Regulation Of Cell Death
Regulation Of Neuron Projection Development
Tagcloud
?
b5
bcat1
carbamoyl
ctnnd1
egfr1
eph
filamin
flna
genego
i2d
interactors
interologous
metadherin
mtdh
nucleolin
pathwaycommons
plec
plectin
pycard
pyd
rpkm
s100a2
serpinb5
signalings
stratifin
subpathway
sum149
sum190
tfrc
Tagcloud (Difference)
?
b5
bcat1
carbamoyl
ctnnd1
egfr1
eph
filamin
flna
genego
i2d
interactors
interologous
metadherin
mtdh
nucleolin
pathwaycommons
plec
plectin
pycard
pyd
rpkm
s100a2
serpinb5
signalings
stratifin
subpathway
sum149
sum190
tfrc
Tagcloud (Intersection)
?