PDLIM1 and AGK

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PDLIM1	AGK
Gene Name		PDZ and LIM domain 1	acylglycerol kinase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor Complex Cytoplasm Cytoskeleton Focal Adhesion	Mitochondrion Mitochondrial Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Coactivator Activity Zinc Ion Binding	Ceramide Kinase Activity NAD+ Kinase Activity Diacylglycerol Kinase Activity ATP Binding Acylglycerol Kinase Activity
	Biological Process	Response To Hypoxia Regulation Of Transcription, DNA-templated Response To Oxidative Stress	Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Glycerolipid Metabolic Process Ceramide Biosynthetic Process Lipid Phosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 RLIM RPS6KA5 STK35 SUPT4H1 VIM	3 interactors: HCK PDLIM1 SNX4
Entrez ID		9124	55750
HPRD ID		09326	08554
Ensembl ID		ENSG00000107438
Uniprot IDs		O00151	A4D1U5 Q53H12
PDB IDs		1X62 2PKT
Enriched GO Terms of Interacting Partners?		Protein Localization To Tight Junction Bergmann Glial Cell Differentiation Protein Localization To Cell Junction Platelet Degranulation Intermediate Filament Organization Actin Crosslink Formation Astrocyte Development Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Tight Junction Assembly Adherens Junction Assembly Actin Filament-based Process Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Response To Wounding Positive Regulation Of Transporter Activity Actin Filament Bundle Assembly Actin Filament-based Movement Histone H2A-S1 Phosphorylation Subthalamic Nucleus Development Prolactin Secreting Cell Differentiation Random Inactivation Of X Chromosome Positive Regulation Of Schwann Cell Proliferation Superior Vena Cava Morphogenesis Apical Junction Assembly Exocytosis Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Cell Proliferation Involved In Outflow Tract Morphogenesis Subthalamus Development Left Lung Morphogenesis Pulmonary Vein Morphogenesis Blood Coagulation Glial Cell Development Hemostasis Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Extraocular Skeletal Muscle Development Pulmonary Myocardium Development Positive Regulation Of Pinocytosis Left Lung Development Cell-cell Junction Assembly Negative Regulation Of Neuron Projection Development	Respiratory Burst After Phagocytosis Leukocyte Migration Involved In Immune Response Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Regulation Of Inflammatory Response Respiratory Burst Involved In Defense Response Regulation Of Vesicle-mediated Transport Regulation Of Podosome Assembly Positive Regulation Of Mast Cell Degranulation Respiratory Burst Positive Regulation Of Mast Cell Activation Positive Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Immune Response Positive Regulation Of Regulated Secretory Pathway Endocytic Recycling Regulation Of Defense Response To Virus By Virus Regulation Of Mast Cell Degranulation Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Mast Cell Activation Peptidyl-tyrosine Autophosphorylation Lipopolysaccharide-mediated Signaling Pathway Regulation Of Regulated Secretory Pathway Regulation Of Actin Cytoskeleton Reorganization Leukocyte Degranulation Regulated Secretory Pathway Positive Regulation Of Exocytosis Regulation Of Phagocytosis Defense Response To Gram-positive Bacterium Regulation Of Immune System Process
Tagcloud ?			acylglycerol anchorage biomarker brdu clinicopathologic clinicopathological colony demonstrating foxo1 gained herein ihc immunoblotting immunochemistry insights luciferase nodule oncogenic overexpressed overexpressing p21cip1 p27kip1 paired shorter tnm transactivity tumorigenicity valuable xenograft
Tagcloud (Difference) ?			acylglycerol anchorage biomarker brdu clinicopathologic clinicopathological colony demonstrating foxo1 gained herein ihc immunoblotting immunochemistry insights luciferase nodule oncogenic overexpressed overexpressing p21cip1 p27kip1 paired shorter tnm transactivity tumorigenicity valuable xenograft
Tagcloud (Intersection) ?