PDLIM1 and STK35

Number of citations of the paper that reports this interaction (PMID 11973348)
16

Data Source:
HPRD (in vitro, two hybrid)

		PDLIM1	STK35
Gene Name		PDZ and LIM domain 1	serine/threonine kinase 35
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor Complex Cytoplasm Cytoskeleton Focal Adhesion	Nucleolus Cytoplasm
	Molecular Function	Transcription Coactivator Activity Zinc Ion Binding	Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Response To Hypoxia Regulation Of Transcription, DNA-templated Response To Oxidative Stress	Protein Phosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 RLIM RPS6KA5 STK35 SUPT4H1 VIM	5 interactors: BMPR1B PDLIM1 SMAD4 SMURF1 TGFBR1
Entrez ID		9124	140901
HPRD ID		09326	11612
Ensembl ID		ENSG00000107438	ENSG00000125834
Uniprot IDs		O00151	Q8TDR2
PDB IDs		1X62 2PKT
Enriched GO Terms of Interacting Partners?		Protein Localization To Tight Junction Bergmann Glial Cell Differentiation Protein Localization To Cell Junction Platelet Degranulation Intermediate Filament Organization Actin Crosslink Formation Astrocyte Development Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Tight Junction Assembly Adherens Junction Assembly Actin Filament-based Process Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Response To Wounding Positive Regulation Of Transporter Activity Actin Filament Bundle Assembly Actin Filament-based Movement Histone H2A-S1 Phosphorylation Subthalamic Nucleus Development Prolactin Secreting Cell Differentiation Random Inactivation Of X Chromosome Positive Regulation Of Schwann Cell Proliferation Superior Vena Cava Morphogenesis Apical Junction Assembly Exocytosis Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Cell Proliferation Involved In Outflow Tract Morphogenesis Subthalamus Development Left Lung Morphogenesis Pulmonary Vein Morphogenesis Blood Coagulation Glial Cell Development Hemostasis Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Extraocular Skeletal Muscle Development Pulmonary Myocardium Development Positive Regulation Of Pinocytosis Left Lung Development Cell-cell Junction Assembly Negative Regulation Of Neuron Projection Development	Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway BMP Signaling Pathway Endothelial Cell Activation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of SMAD Protein Import Into Nucleus Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of SMAD Protein Import Into Nucleus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Cardiac Epithelial To Mesenchymal Transition Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Pattern Specification Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neuron Fate Commitment Regulation Of BMP Signaling Pathway Tissue Development Cellular Response To Growth Factor Stimulus Regulation Of Cartilage Development Positive Regulation Of Protein Import Into Nucleus Response To Growth Factor Palate Development Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cell Proliferation Mesenchymal Cell Development Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cell Morphogenesis Involved In Differentiation Mesenchymal Cell Differentiation Regulation Of Gene Expression Ovarian Cumulus Expansion Nephrogenic Mesenchyme Morphogenesis Negative Regulation Of Chondrocyte Proliferation Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Regulation Of Protein Localization To Nucleus Positive Regulation Of Apoptotic Signaling Pathway
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